KEGG   DRUG: Paramethadione
Entry
D00495                      Drug                                   
Name
Paramethadione (INN);
Paradione (TN)
Formula
C7H11NO3
Exact mass
157.0739
Mol weight
157.17
Structure
Simcomp
Class
Neuropsychiatric agent
 DG03199  Antiepileptic agent
  DG02032  Oxazolidine antiepileptic
Remark
Same as: C07411
ATC code: N03AC01
Efficacy
Anticonvulsant
Comment
Oxazolidine derivative
Target
CACNA1-L [HSA:775 776 778 779] [KO:K04850 K04851 K04853 K04857]
  Pathway
hsa04010  MAPK signaling pathway
hsa04020  Calcium signaling pathway
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N03 ANTIEPILEPTICS
   N03A ANTIEPILEPTICS
    N03AC Oxazolidine derivatives
     N03AC01 Paramethadione
      D00495  Paramethadione (INN)
Drug groups [BR:br08330]
 Neuropsychiatric agent
  DG03199  Antiepileptic agent
   DG02032  Oxazolidine antiepileptic
    D00495  Paramethadione
Target-based classification of drugs [BR:br08310]
 Ion channels
  Voltage-gated ion channels
   Calcium channels
    CACNA1-L
     D00495  Paramethadione (INN)
Other DBs
CAS: 115-67-3
PubChem: 7847561
ChEBI: 7921
LigandBox: D00495
NIKKAJI: J5.271J
LinkDB
KCF data

ATOM        11
            1   C1z C    19.0262  -15.1147
            2   C5x C    20.1590  -15.9290
            3   O7x O    17.9094  -15.9491
            4   C1b C    17.9872  -14.1955
            5   C1a C    19.6966  -13.7719
            6   N1y N    19.7416  -17.2551
            7   O5x O    21.4753  -15.4890
            8   C7x C    18.3493  -17.2654
            9   C1a C    18.2776  -12.8380
            10  C1a C    20.5649  -18.3757
            11  O6a O    17.5463  -18.3947
BOND        11
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     1   5 1
            5     2   6 1
            6     2   7 2
            7     3   8 1
            8     4   9 1
            9     6  10 1
            10    8  11 2
            11    6   8 1

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