| Entry |
|
|---|
| Name |
Propofol (JAN/USAN/INN);
Diprivan (TN)
|
|---|
| Product |
|
|---|
| Generic |
|
|---|
| Formula |
C12H18O
|
|---|
| Exact mass |
178.1358
|
|---|
| Mol weight |
178.2707
|
|---|
| Structure |
   |
|---|
| Simcomp |
 |
|---|
| Class |
|
|---|
| Remark |
| Therapeutic category: | 1119 |
| Product (DG00797): | D00549<JP/US> |
|
|---|
| Efficacy |
Anesthetic (intravenous), GABA-A receptor agonist |
|---|
| Comment |
Isopropylphenol derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07230 | GABA-A receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N01 ANESTHETICS
N01A ANESTHETICS, GENERAL
N01AX Other general anesthetics
N01AX10 Propofol
D00549 Propofol (JAN/USAN/INN) <JP/US>
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
11 Agents affecting central nervous system
111 General anesthetics
1119 Others
D00549 Propofol (JAN/USAN/INN)
Target-based classification of drugs [BR:br08310]
Ion channels
Ligand-gated ion channels
GABA (ionotropic)
GABR
D00549 Propofol (JAN/USAN/INN) <JP/US>
Drug classes of therapeutic agents [br08360.html]
Anesthetics, analgesics and anti-inflammatory drugs
D00549
Prodrugs [br08324.html]
D00549
 |
|---|
| Other DBs |
|
|---|
| LinkDB |
 |
|---|
| KCF data |
ATOM 13
1 C8y C 24.1226 -18.3979
2 C8y C 25.3400 -17.6989
3 C1c C 22.9112 -17.6989
4 C8x C 24.1226 -19.7958
5 C8y C 26.5514 -18.3979
6 O1a O 25.3457 -16.3010
7 C1a C 22.9112 -16.3010
8 C1a C 21.6996 -18.3979
9 C8x C 25.3400 -20.5005
10 C1c C 27.7688 -17.6989
11 C8x C 26.5514 -19.7958
12 C1a C 28.9804 -18.3979
13 C1a C 27.7688 -16.3010
BOND 13
1 1 2 1
2 1 3 1
3 1 4 2
4 2 5 2
5 2 6 1
6 3 7 1
7 3 8 1
8 4 9 1
9 5 10 1
10 5 11 1
11 10 12 1
12 10 13 1
13 9 11 2
|
|---|
