| Entry |
|
|---|
| Name |
Propofol (JAN/USP/INN);
Diprivan (TN) |
|---|
| Product |
|
|---|
| Generic |
PROPOFOL (A-S Medication Solutions), PROPOFOL (Actavis Pharma), PROPOFOL (Civica), PROPOFOL (Civica), PROPOFOL (General Injectables & Vaccines), PROPOFOL (General Injectables and Vaccines), PROPOFOL (HF Acquisition Co LLC), PROPOFOL (HF Acquisition Co LLC), PROPOFOL (HF Acquisition Co LLC), PROPOFOL (Hikma Pharmaceuticals USA), PROPOFOL (Hospira), PROPOFOL (Pfizer Laboratories Div Pfizer), PROPOFOL (Sagent Pharmaceuticals), PROPOFOL INJECTABLE EMULSION (Dr. Reddy's Laboratories) |
|---|
| Formula |
C12H18O
|
|---|
| Exact mass |
178.1358
|
|---|
| Mol weight |
178.2707
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
|
|---|
| Remark |
| Therapeutic category: | 1119 |
| Product (DG00797): | D00549<JP/US> |
|
|---|
| Efficacy |
Anesthetic (intravenous), GABA-A receptor agonist |
|---|
| Comment |
Isopropylphenol derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07230 | GABA-A receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N01 ANESTHETICS
N01A ANESTHETICS, GENERAL
N01AX Other general anesthetics
N01AX10 Propofol
D00549 Propofol (JAN/USP/INN) <JP/US>
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
11 Agents affecting central nervous system
111 General anesthetics
1119 Others
D00549 Propofol (JAN/USP/INN)
Target-based classification of drugs [BR:br08310]
Ion channels
Ligand-gated ion channels
GABA (ionotropic)
GABR
D00549 Propofol (JAN/USP/INN) <JP/US>
Prodrugs [br08324.html]
D00549
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 13
1 C8y C 24.1226 -18.3979
2 C8y C 25.3400 -17.6989
3 C1c C 22.9112 -17.6989
4 C8x C 24.1226 -19.7958
5 C8y C 26.5514 -18.3979
6 O1a O 25.3457 -16.3010
7 C1a C 22.9112 -16.3010
8 C1a C 21.6996 -18.3979
9 C8x C 25.3400 -20.5005
10 C1c C 27.7688 -17.6989
11 C8x C 26.5514 -19.7958
12 C1a C 28.9804 -18.3979
13 C1a C 27.7688 -16.3010
BOND 13
1 1 2 1
2 1 3 1
3 1 4 2
4 2 5 2
5 2 6 1
6 3 7 1
7 3 8 1
8 4 9 1
9 5 10 1
10 5 11 1
11 10 12 1
12 10 13 1
13 9 11 2
|
|---|
