A型ボツリヌス毒素 (JAN);
Botulinum toxin type A (JAN)

ボトックス (グラクソ・スミスクライン), ボトックスビスタ (アッヴィ)
商品一覧

DAXXIFY (Revance Therapeutics), DYSPORT (Galderma Laboratories), DYSPORT (Ipsen Biopharmaceuticals)

Clostridium botulinum A [TAX:36826]

骨格筋弛緩薬, 神経筋遮断薬

嫌気性グラム陽性桿菌のA型ボツリヌス菌により産生される毒素

SNAP25 [HSA:6616] [KO:K18211]

DDI search

B型ボツリヌス毒素 (JAN);
RimabotulinumtoxinB (USAN);
Botulinum toxin type B (JAN)

Clostridium botulinum B [TAX:36827]

骨格筋弛緩薬

嫌気性グラム陽性桿菌のB型ボツリヌス菌により産生される毒素

SNAP25 [HSA:6616] [KO:K18211]

DDI search

プラボツリナムトキシンA;
PrabotulinumtoxinA (USAN);
PrabotulinumtoxinA-xvfs

C6760H10447N1743O2010S32

149228.9908

149320.87

骨格筋弛緩薬

SNAP25 [HSA:6616] [KO:K18211]

DDI search

オナボツリナムトキシンA;
エバボツリナムトキシンA;
OnabotulinumtoxinA (USAN);
EvabotulinumtoxinA (USAN)

BOTOX (Allergan), BOTOX COSMETIC (Allergan)

C6708 H10363N1729O1995S32

148084.3667

148175.57

(Light chain)
PFVNKQFNYK DPVNGVDIAY IKIPNAGQMQ PVKAFKIHNK IWVIPERDTF TNPEEGDLNP
PPEAKQVPVS YYDSTYLSTD NEKDNYLKGV TKLFERIYST DLGRMLLTSI VRGIPFWGGS
TIDTELKVID TNCINVIQPD GSYRSEELNL VIIGPSADII QFECKSFGHE VLNLTRNGYG
STQYIRFSPD FTFGFEESLE VDTNPLLGAG KFATDPAVTL AHELIHAGHR LYGIAINPNR
VFKVNTNAYY EMSGLEVSFE ELRTFGGHDA KFIDSLQENE FRLYYYNKFK DIASTLNKAK
SIVGTTASLQ YMKNVFKEKY LLSEDTSGKF SVDKLKFDKL YKMLTEIYTE DNFVKFFKVL
NRKTYLNFDK AVFKINIVPK VNYTIYDGFN LRNTNLAANF NGQNTEINNM NFTKLKNFTG
LFEFYKLLCV RGIITSK
(Heavy chain)
ALNDLCIKVN NWDLFFSPSE DNFTNDLNKG EEITSDTNIE AAEENISLDL IQQYYLTFNF
DNEPENISIE NLSSDIIGQL ELMPNIERFP NGKKYELDKY TMFHYLRAQE FEHGKSRIAL
TNSVNEALLN PSRVYTFFSS DYVKKVNKAT EAAMFLGWVE QLVYDFTDET SEVSTTDKIA
DITIIIPYIG PALNIGNMLY KDDFVGALIF SGAVILLEFI PEIAIPVLGT FALVSYIANK
VLTVQTIDNA LSKRNEKWDE VYKYIVTNWL AKVNTQIDLI RKKMKEALEN QAEATKAIIN
YQYNQYTEEE KNNINFNIDD LSSKLNESIN KAMININKFL NQCSVSYLMN SMIPYGVKRL
EDFDASLKDA LLKYIYDNRG TLIGQVDRLK DKVNNTLSTD IPFQLSKYVD NQRLLSTFTE
YIKNIINTSI LNLRYESNHL IDLSRYASKI NIGSKVNFDP IDKNQIQLFN LESSKIEVIL
KNAIVYNSMY ENFSTSFWIR IPKYFNSISL NNEYTIINCM ENNSGWKVSL NYGEIIWTLQ
DTQEIKQRVV FKYSQMINIS DYINRWIFVT ITNNRLNNSK IYINGRLIDQ KPISNLGNIH
ASNNIMFKLD GCRDTHRYIW IKYFNLFDKE LNEKEIKDLY DNQSNSGILK DFWGDYLQYD
KPYYMLNLYD PNKYVDVNNV GIRGYMYLKG PRGSVMTTNI YLNSSLYRGT KFIIKKYASG
NKDNIVRNND RVYINVVVKN KEYRLATNAS QAGVEKILSA LEIPDVGNLS QVVVMKSKND
QGITNKCKMN LQDNNGNDIG FIGFHQFNNI AKLVASNWYN RQIERSSRTL GCSWEFIPVD
DGWGERPL

抗片頭痛薬, 骨格筋弛緩薬

DDI search

アボボツリナムトキシンA;
AbobotulinumtoxinA (USAN)

Clostridium botulinum A [TAX:36826]

骨格筋弛緩薬

DDI search

インコボツリヌストキシンA (JAN);
インコボツリナムトキシンA;
Incobotulinumtoxin A (JAN/USAN);
Onaclostox

ゼオマイン (帝人ファーマ), ゼオマイン (帝人ファーマ)
商品一覧

XEOMIN (Merz North America), XEOMIN (Merz Pharmaceuticals)

C2286H3500N578O666S9. C4422H6863N1151O1329S23

148084.3667

148175.57

骨格筋弛緩薬, SNAP25タンパク阻害薬

上肢痙縮, 下肢痙縮, 慢性流涎治療薬

SNAP25 [HSA:6616] [KO:K18211]

DDI search

ダキシボツリナムトキシンA;
DaxibotulinumtoxinA (USAN);
DaxibotulinumtoxinA-lanm

C6708H10359N1729O1995S32

148080.3354

148171.53

抗片頭痛薬, 骨格筋弛緩薬

SNAP25 [HSA:6616] [KO:K18211]

DDI search

レチボツリナムトキシンA;
LetibotulinumtoxinA (USAN);
LetibotulinumtoxinA-wlbg

骨格筋弛緩薬

SNAP25 [HSA:6616] [KO:K18211]

DDI search

ニボボツリナムトキシンA;
NivobotulinumtoxinA (USAN)

骨格筋弛緩薬

DDI search

トレニボツリヌストキシンE;
TrenibotulinumtoxinE (JAN/USAN);
Botulin E

C6452H9998N1702O1973S23

143626.7908

143714.16

MPKINSFNYN DPVNDRTILY IKPGGCQEFY KSFNIMKNIW IIPERNVIGT TPQDFHPPTS
LKNGDSSYYD PNYLQSDEEK DRFLKIVTKI FNRINNNLSG GILLEELSKA NPYLGNDNTP
DNQFHIGDAS AVEIKFSNGS QHILLPNVII MGAEPDLFET NSSNISLRNN YMPSNHGFGS
IAIVTFSPEY SFRFNDNSIN EFIQDPALTL MHELIHSLHG LYGAKGITTT CIITQQQNPL
ITNRKGINIE EFLTFGGNDL NIITVAQYND IYTNLLNDYR KIASKLSKVQ VSNPQLNPYK
DIFQEKYGLD KDASGIYSVN INKFDDILKK LYSFTEFDLA TKFQVKCRET YIGQYKYFKL
SNLLNDSIYN ISEGYNINNL KVNFRGQNAN LNPRIIKPIT GRGLVKKIIR FCKNIVSVKG
IRKSICIEIN NGELFFVASE NSYNDDNINT PKEIDDTVTS NNNYENDLDQ VILNFNSESA
PGLSDEKLNL TIQNDAYIPK YDSNGTSDIE QHDVNELNVF FYLDAQKVPE GENNVNLTSS
IDTALLEQPK IYTFFSSEFI NNVNKPVQAA LFVSWIQQVL VDFTTEANQK STVDKIADIS
IVVPYIGLAL NIGNEAQKGN FKDALELLGA GILLEFEPEL LIPTILVFTI KSFLGSSDNK
NKVIKAINNA LKERDEKWKE VYSFIVSNWM TKINTQFNKR KEQMYQALQN QVNAIKTIIE
SKYNSYTLEE KNELTNKYDI KQIENELNQK VSIAMNNIDR FLTESSISYL MKLINEVKIN
KLREYDENVK TYLLNYIIQH GSILGESQQE LNSMVTDTLN NSIPFKLSSY TDDKILISYF
NKFFKRIKSS SVLNMRYKND KYVDTSGYDS NININGDVYK YPTNKNQFGI YNDKLSEVNI
SQNDYIIYDN KYKNFSISFW VRIPNYDNKI VNVNNEYTII NCMRDNNSGW KVSLNHNEII
WTLQDNAGIN QKLAFNYGNA NGISDYINKW IFVTITNDRL GDSKLYINGN LIDQKSILNL
GNIHVSDNIL FKIVNCSYTR YIGIRYFNIF DKELDETEIQ TLYSNEPNTN ILKDFWGNYL
LYDKEYYLLN VLKPNNFIDR RKDSTLSINN IRSTILLANR LYSGIKVKIQ RVNNSSTNDN
LVRKNDQVYI NFVASKTHLF PLYADTATTN KEKTIKISSS GNRFNQVVVM NSVGNNCTMN
FKNNNGNNIG LLGFKADTVV ASTWYYTHMR DHTNSNGCFW NFISEEHGWQ EK

骨格筋弛緩薬

DDI search