| Entry |
|
|---|
| Name |
Methylatropine nitrate (USAN);
Atropine methonitrate (JAN/INN);
Ekomine (TN) |
|---|
| Formula |
C18H26NO3. NO3
|
|---|
| Exact mass |
366.1791
|
|---|
| Mol weight |
366.41
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
|
|---|
| Remark |
|
|---|
| Efficacy |
Antispasmodic, Muscarinic acetylcholine receptor antagonist |
|---|
| Comment |
Tropane derivative, Quaternary ammonium compound
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A03 DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
A03B BELLADONNA AND DERIVATIVES, PLAIN
A03BB Belladonna alkaloids, semisynthetic, quaternary ammonium compounds
A03BB02 Methylatropine
D01077 Methylatropine nitrate (USAN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG01242 Methylatropine
D01077 Methylatropine nitrate
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Acetylcholine (muscarinic)
CHRM
D01077 Methylatropine nitrate (USAN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG01242 Methylatropine
|
|---|
| Other DBs |
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|---|
| LinkDB |
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|---|
| KCF data |
ATOM 26
1 N2b N 32.1276 -18.8381 #+
2 O3a O 32.1276 -17.7275
3 O3a O 30.8418 -19.6973 #-
4 O3a O 33.4778 -19.5804 #-
5 C1x C 18.2238 -19.1608
6 C1x C 18.5519 -17.9891
7 C1y C 19.3955 -18.8796
8 C1y C 19.7236 -17.7079
9 N2y N 18.4582 -16.3956 #+
10 C1x C 21.2702 -18.8796
11 C1x C 20.9890 -17.7079
12 C1y C 22.3013 -19.4420
13 O7a O 23.3793 -20.3325
14 C7a C 24.5979 -20.3325
15 C1c C 25.2072 -19.2545
16 O6a O 25.2072 -21.4573
17 C8y C 26.4258 -19.2545
18 C1b C 24.5979 -18.2234
19 O1a O 25.2072 -17.1455
20 C8x C 27.1320 -20.4782
21 C8x C 28.5320 -20.4785
22 C8x C 29.2322 -19.2662
23 C8x C 28.5261 -18.0425
24 C8x C 27.1261 -18.0422
25 C1a C 17.7091 -15.2114
26 C1a C 17.2289 -17.0083
BOND 27
1 1 2 2
2 1 3 1
3 1 4 1
4 5 6 1
5 5 7 1
6 6 8 1
7 7 9 1
8 7 10 1
9 8 11 1
10 10 12 1
11 12 13 1 #Down
12 13 14 1
13 14 15 1
14 14 16 2
15 15 17 1
16 15 18 1
17 18 19 1
18 8 9 1
19 11 12 1
20 17 20 2
21 20 21 1
22 21 22 2
23 22 23 1
24 23 24 2
25 17 24 1
26 9 25 1
27 9 26 1
|
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