| Entry |
|
|---|
| Name |
Oxendolone (JAN/USAN/INN);
Prostetin (TN) |
|---|
| Formula |
C20H30O2
|
|---|
| Exact mass |
302.2246
|
|---|
| Mol weight |
302.45
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Antineoplastic
DG01591 Androgen receptor antagonist
DG01623 Steroid-type antiandrogen
|
|---|
| Efficacy |
Antidysuria, Androgen receptor antagonist |
|---|
| Comment |
Anti-androgen (benign prostatic hypertrophy)
|
|---|
| Target |
|
|---|
| Structure map |
| map07226 | Progesterone, androgen and estrogen receptor agonists/antagonists |
|
|---|
| Brite |
Drug groups [BR:br08330]
Antineoplastic
DG01591 Androgen receptor antagonist
DG01623 Steroid-type antiandrogen
D01329 Oxendolone
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Estrogen like receptors
3-Ketosteroid receptor
NR3C4 (AR)
D01329 Oxendolone (JAN/USAN/INN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 22
1 C1x C 20.3611 -18.0591
2 C5x C 20.3611 -19.4272
3 C2x C 21.5489 -20.1113
4 C1x C 21.5489 -17.3750
5 C1y C 22.7296 -18.0591
6 C2y C 22.7238 -19.4272
7 C1x C 23.9058 -20.1163
8 C1x C 25.0935 -19.4374
9 C1y C 23.9175 -17.3799
10 C1y C 25.0937 -18.0720
11 C1x C 25.1161 -15.3428
12 C1x C 23.9287 -16.0154
13 C1z C 26.2922 -16.0348
14 C1y C 26.3458 -17.3952
15 C1x C 28.6321 -17.4237
16 C1y C 28.6486 -16.0633
17 C1y C 27.4786 -15.3688
18 O1a O 27.4952 -14.0008
19 C1a C 26.3531 -14.6661
20 O5x O 19.1767 -20.1118
21 C1b C 29.8417 -15.3937
22 C1a C 31.0182 -16.0920
BOND 25
1 11 12 1
2 12 9 1
3 2 3 1
4 3 6 2
5 5 6 1
6 6 7 1
7 7 8 1
8 13 14 1
9 15 16 1
10 16 17 1
11 17 13 1
12 14 15 1
13 8 10 1
14 17 18 1 #Up
15 9 5 1
16 13 19 1 #Up
17 5 4 1
18 4 1 1
19 1 2 1
20 2 20 2
21 9 10 1
22 16 21 1 #Up
23 10 14 1
24 21 22 1
25 13 11 1
|
|---|
