KEGG   DRUG: Prifinium bromideHelp
Entry
D01377                      Drug                                   

Name
Prifinium bromide (JAN/INN);
Padrin (TN)
Formula
C22H28N. Br
Exact mass
385.1405
Mol weight
386.3684
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Neuropsychiatric agent
 DG01491  Muscarinic cholinergic receptor antagonist
Gastrointestinal agent
 DG01975  Agents for peptic ulcer
Remark
Same as: C12814
ATC code: A03AB18
Efficacy
Antispasmodic, Muscarinic acetylcholine receptor antagonist
Comment
Quaternary ammonium compound
Target
  Pathway
hsa04020  Calcium signaling pathway
hsa04024  cAMP signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
Interaction
Drug interaction
Structure map
map07038  Antiulcer drugs
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A03 DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
   A03A DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
    A03AB Synthetic anticholinergics, quaternary ammonium compounds
     A03AB18 Prifinium bromide
      D01377  Prifinium bromide (JAN/INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    CHRM
     D01377  Prifinium bromide (JAN/INN)
BRITE hierarchy
Other DBs
CAS: 4630-95-9
PubChem: 7848440
ChEBI: 32052
ChEMBL: CHEMBL1213353
LigandBox: D01377
NIKKAJI: J244.762B
LinkDB All DBs
KCF data Show

ATOM        24
            1   C8x C    18.8076  -20.2443
            2   C8x C    18.8076  -21.6440
            3   C8x C    20.0227  -22.3438
            4   C8x C    21.2307  -21.6440
            5   C8y C    21.2307  -20.2443
            6   C8x C    20.0227  -19.5445
            7   C2c C    22.4433  -19.5453
            8   C8y C    23.6550  -20.2462
            9   C2y C    22.4444  -18.1457
            10  C8x C    23.6484  -21.6438
            11  C8x C    24.8601  -22.3445
            12  C8x C    26.0726  -21.6457
            13  C8x C    26.0736  -20.2460
            14  C8x C    24.8621  -19.5452
            15  C1x C    23.5749  -17.3210
            16  C1x C    23.1435  -15.9894
            17  N2y N    21.7439  -15.9885 #+
            18  C1y C    21.3102  -17.3193
            19  C1a C    19.9786  -17.7504
            20  C1b C    22.1018  -14.6245
            21  C1b C    20.3417  -15.9817
            22  C1a C    23.4519  -14.2553
            23  C1a C    19.6478  -14.7662
            24  X   Br   27.2622  -16.0806 #-
BOND        25
            1     6   1 1
            2     8  10 2
            3    10  11 1
            4    11  12 2
            5    12  13 1
            6    13  14 2
            7    14   8 1
            8     5   7 1
            9     7   8 1
            10    9  15 1
            11   15  16 1
            12   16  17 1
            13   17  18 1
            14   18   9 1
            15    1   2 2
            16   18  19 1
            17    7   9 2
            18   17  20 1
            19    2   3 1
            20   17  21 1
            21    3   4 2
            22   20  22 1
            23    4   5 1
            24   21  23 1
            25    5   6 2

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