| Entry |
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| Name |
Opipramol hydrochloride (JAN/USAN);
Insidon (TN) |
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| Formula |
C23H29N3O. 2HCl
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| Exact mass |
435.1844
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| Mol weight |
436.41
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| Structure |
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| Simcomp |
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| Class |
Neuropsychiatric agent
DG01730 Non-selective monoamine reuptake inhibitor
DG01728 Tricyclic antidepressant
DG01560 Sigma receptor agonist
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
|
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| Remark |
|
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| Efficacy |
Antidepressant, Antipsychotic |
|---|
| Target |
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
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| Interaction |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N06 PSYCHOANALEPTICS
N06A ANTIDEPRESSANTS
N06AA Non-selective monoamine reuptake inhibitors
N06AA05 Opipramol
D01477 Opipramol hydrochloride (JAN/USAN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01730 Non-selective monoamine reuptake inhibitor
DG00930 Opipramol
D01477 Opipramol hydrochloride
DG01728 Tricyclic antidepressant
DG00930 Opipramol
D01477 Opipramol hydrochloride
DG01560 Sigma receptor agonist
DG00930 Opipramol
D01477 Opipramol hydrochloride
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG00930 Opipramol
D01477 Opipramol hydrochloride
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
DG00930 Opipramol
D01477 Opipramol hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Dopamine
DRD2
D01477 Opipramol hydrochloride (JAN/USAN)
Histamine
HRH1
D01477 Opipramol hydrochloride (JAN/USAN)
Serotonin
HTR2
D01477 Opipramol hydrochloride (JAN/USAN)
Transporters
Other transporters
Auxiliary transport proteins (TC:8.A)
SIGMAR1
D01477 Opipramol hydrochloride (JAN/USAN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01730 Non-selective monoamine reuptake inhibitor
DG00930 Opipramol
DG01728 Tricyclic antidepressant
DG00930 Opipramol
DG01560 Sigma receptor agonist
DG00930 Opipramol
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG00930 Opipramol
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
DG00930 Opipramol
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 29
1 C2x C 13.6952 -13.2773
2 C8y C 12.8508 -12.1647
3 C8y C 13.1869 -10.8042
4 N1y N 14.4514 -10.2245
5 C2x C 15.1048 -13.3026
6 C8y C 15.7083 -10.8485
7 C8y C 15.9956 -12.2210
8 C8x C 12.1770 -9.8331
9 C8x C 10.8314 -10.2223
10 C8x C 10.4953 -11.5828
11 C8x C 11.5051 -12.5536
12 C8x C 17.3304 -12.6593
13 C8x C 18.3775 -11.7223
14 C8x C 18.0904 -10.3498
15 C8x C 16.7553 -9.9115
16 C1b C 14.4031 -8.8458
17 C1b C 15.6304 -8.1628
18 C1b C 16.8020 -8.8642
19 N1y N 18.0275 -8.1823
20 C1x C 19.2559 -8.9179
21 C1x C 20.4794 -8.2374
22 N1y N 20.5018 -6.8376
23 C1x C 19.2734 -6.1019
24 C1x C 18.0499 -6.7824
25 C1b C 21.7219 -6.1590
26 C1b C 22.9071 -6.8691
27 O1a O 24.1214 -6.1939
28 X Cl 23.1726 -11.1629
29 X Cl 23.1726 -11.1629
BOND 30
1 3 4 1
2 1 5 2
3 4 6 1
4 2 3 1
5 5 7 1
6 1 2 1
7 6 7 1
8 3 8 2
9 8 9 1
10 9 10 2
11 10 11 1
12 2 11 2
13 7 12 2
14 12 13 1
15 13 14 2
16 14 15 1
17 6 15 2
18 4 16 1
19 16 17 1
20 17 18 1
21 18 19 1
22 19 20 1
23 20 21 1
24 21 22 1
25 22 23 1
26 23 24 1
27 19 24 1
28 22 25 1
29 25 26 1
30 26 27 1
BRACKET 1 21.4900 -11.9700 21.4900 -10.2900
1 24.0800 -10.2900 24.0800 -11.9700
1 2
ORIGINAL 1 28
REPEAT 1 29
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