| Entry |
|
|---|
| Name |
Desmopressin acetate (USP);
Desmopressin acetate hydrate (JAN);
Desmopressin acetate trihydrate;
DDAVP (TN);
Minirinmelt (TN);
Stimate (TN) |
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| Product |
|
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| Generic |
DESMOPRESSIN ACETATE (American Health Packaging), DESMOPRESSIN ACETATE (Apotex Corp.), DESMOPRESSIN ACETATE (Apotex Corp.), DESMOPRESSIN ACETATE (Aurobindo Pharma Limited), DESMOPRESSIN ACETATE (Avenacy), DESMOPRESSIN ACETATE (Bauch & Lomb Incorporated), DESMOPRESSIN ACETATE (BluePoint Laboratories), DESMOPRESSIN ACETATE (Bryant Ranch Prepack), DESMOPRESSIN ACETATE (Bryant Ranch Prepack), DESMOPRESSIN ACETATE (Bryant Ranch Prepack), DESMOPRESSIN ACETATE (Dr. Reddy's Laboratories), DESMOPRESSIN ACETATE (Dr.Reddys' Laboratories), DESMOPRESSIN ACETATE (Fresenius Kabi USA), DESMOPRESSIN ACETATE (Fresenius Kabi USA), DESMOPRESSIN ACETATE (Gland Pharma Limited), DESMOPRESSIN ACETATE (Gland Pharma Limited), DESMOPRESSIN ACETATE (Glenmark Pharmaceuticals), DESMOPRESSIN ACETATE (Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals), DESMOPRESSIN ACETATE (KVK-TECH), DESMOPRESSIN ACETATE (Meitheal Pharmaceuticals), DESMOPRESSIN ACETATE (Northwind Pharmaceuticals), DESMOPRESSIN ACETATE (REMEDYREPACK), DESMOPRESSIN ACETATE (REMEDYREPACK), DESMOPRESSIN ACETATE (Sagent Pharmaceuticals), DESMOPRESSIN ACETATE (Sagent Pharmaceuticals), DESMOPRESSIN ACETATE (Sun Pharmaceutical Industries Limited), DESMOPRESSIN ACETATE (Sun Pharmaceutical Industries Limited), DESMOPRESSIN ACETATE (Sun Pharmaceutical Industries), DESMOPRESSIN ACETATE (Sun Pharmaceutical Industries), DESMOPRESSIN ACETATE (UBI Pharma), DESMOPRESSIN ACETATE (UBI Pharma), DESMOPRESSIN ACETATE (XGen Pharmaceuticals DJB) |
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| Formula |
C46H64N14O12S2. C2H4O2. 3H2O
|
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| Exact mass |
1182.4798
|
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| Mol weight |
1183.32
|
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| Structure |
|
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| Simcomp |
|
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| Class |
Cardiovascular agent
DG01952 Vasopressin analog
|
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| Remark |
| Therapeutic category: | 2419 |
| Product (DG00497): | D02235<JP/US> |
|
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| Efficacy |
Antidiuretic, Arginine vasopressin receptor agonist |
|---|
| Disease |
Hemophilia A [DS: H00219] von Willebrand's disease type 1 [DS: H02092] Central diabetes insipidus [DS: H00253] |
|---|
| Comment |
Arg-vasopressin [DR: D02983] derivative
Treatment of nocturia
|
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| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04610 | Complement and coagulation cascades |
| hsa04962 | Vasopressin-regulated water reabsorption |
|
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| Network |
|
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| Interaction |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
H01 PITUITARY AND HYPOTHALAMIC HORMONES AND ANALOGUES
H01B POSTERIOR PITUITARY LOBE HORMONES
H01BA Vasopressin and analogues
H01BA02 Desmopressin
D02235 Desmopressin acetate (USP) <JP/US>
USP drug classification [BR:br08302]
Blood Products and Modifiers
Blood Component Deficiency/ Replacement
Blood Component Deficiency/ Replacement, Hemophilia A
Desmopressin
D02235 Desmopressin acetate (USP)
Blood Component Deficiency/ Replacement, von Willebrand Disease
Desmopressin
D02235 Desmopressin acetate (USP)
Hormonal Agents, Stimulant/Replacement/Modifying (Pituitary)
Desmopressin
D02235 Desmopressin acetate (USP)
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
24 Hormones
241 Pituitary hormone preparations
2419 Others
D02235 Desmopressin acetate (USP); Desmopressin acetate hydrate (JAN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01952 Vasopressin analog
DG00497 Desmopressin
D02235 Desmopressin acetate
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Vasopressin
AVPR2
D02235 Desmopressin acetate (USP) <JP/US>
Not elsewhere classified
Organismal systems
Complement and coagulation
F8
D02235 Desmopressin acetate (USP) <JP/US>
Drug groups [BR:br08330]
Cardiovascular agent
DG01952 Vasopressin analog
DG00497 Desmopressin
|
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| Other DBs |
|
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| LinkDB |
|
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| KCF data |
ATOM 81
1 C1a C 32.3832 -21.0137
2 C6a C 33.5970 -20.3133
3 O6a O 34.8108 -21.0137
4 O6a O 33.5970 -18.9128
5 N1y N 18.8548 -17.5639
6 C1y C 19.2754 -18.8259
7 C5a C 18.8548 -16.2553
8 C1x C 17.5461 -17.6107
9 C5a C 20.4440 -19.4802
10 C1x C 18.2472 -19.6205
11 C1y C 20.0233 -15.6009
12 O5a O 17.7331 -15.6009
13 C1x C 17.1722 -18.8726
14 N1b N 21.5657 -18.8259
15 O5a O 20.4440 -20.7889
16 N1x N 20.0233 -14.2923
17 C1x C 21.1450 -16.2553
18 C1c C 22.7342 -19.4802
19 C5x C 21.1450 -13.5911
20 S3x S 22.3135 -15.6009
21 C5a C 22.7342 -20.7889
22 C1b C 23.8559 -18.8259
23 C1y C 21.1450 -12.2825
24 O5x O 22.3135 -14.2923
25 S3x S 23.4353 -16.2553
26 N1b N 23.8559 -21.4434
27 O5a O 21.5657 -21.4434
28 C1b C 25.0244 -19.4802
29 N1x N 20.0233 -11.6281
30 C1b C 22.3135 -11.6281
31 C1x C 24.5570 -15.6009
32 C1b C 25.0244 -20.7889
33 C1b C 26.1461 -18.8259
34 C5x C 20.0233 -10.3194
35 C5a C 23.4353 -12.2825
36 C1x C 25.7255 -16.2553
37 C1y C 22.0331 -9.5716
38 O5x O 18.8548 -9.6650
39 N1a N 24.5570 -11.6281
40 O5a O 23.4353 -13.5911
41 C5x C 26.8473 -15.6009
42 N1x N 23.9027 -10.3194
43 C1b C 22.0331 -7.8890
44 N1x N 28.0157 -16.2553
45 O5x O 26.8473 -14.2923
46 C5x C 25.7722 -9.5716
47 C1b C 20.9113 -7.1879
48 C1y C 29.1375 -15.6009
49 C1y C 28.0157 -10.3194
50 O5x O 25.7722 -8.2628
51 C5a C 19.7429 -7.8422
52 C1b C 30.3059 -16.2553
53 C5x C 29.1375 -14.2923
54 C1b C 29.3244 -9.6650
55 N1x N 28.0157 -13.3810
56 N1a N 18.6211 -7.1412
57 O5a O 19.7429 -9.1509
58 C8y C 31.4276 -15.6009
59 O5x O 30.3059 -13.5911
60 C8y C 30.4929 -10.2726
61 C8x C 32.5494 -16.2553
62 C8x C 31.4276 -14.2455
63 C8x C 30.4929 -11.5813
64 C8x C 31.6613 -9.5716
65 C8x C 33.7178 -15.6009
66 C8x C 32.5494 -13.5911
67 C8x C 31.6613 -12.2357
68 C8x C 32.7831 -10.2726
69 C8y C 33.7178 -14.2455
70 C8x C 32.7831 -11.5813
71 O1a O 34.8396 -13.5911
72 C5a C 26.1929 -21.4901
73 N1a N 27.4548 -20.7889
74 O5a O 26.1929 -22.8922
75 N1b N 27.3614 -19.5270
76 C2c C 28.5765 -18.8259
77 N1a N 29.7918 -19.5270
78 N2a N 28.5765 -17.4237
79 O0 O 34.2778 -22.8153
80 O0 O 34.2778 -22.8153
81 O0 O 34.2778 -22.8153
BOND 80
1 1 2 1
2 2 3 1
3 2 4 2
4 5 6 1
5 5 7 1
6 5 8 1
7 6 9 1
8 6 10 1
9 7 11 1
10 7 12 2
11 8 13 1
12 9 14 1
13 9 15 2
14 11 16 1
15 11 17 1
16 14 18 1
17 16 19 1
18 17 20 1
19 18 21 1
20 18 22 1
21 19 23 1
22 19 24 2
23 20 25 1
24 21 26 1
25 21 27 2
26 22 28 1
27 23 29 1
28 23 30 1
29 25 31 1
30 26 32 1
31 28 33 1
32 29 34 1
33 30 35 1
34 31 36 1
35 34 37 1
36 34 38 2
37 35 39 1
38 35 40 2
39 36 41 1
40 37 42 1
41 37 43 1
42 41 44 1
43 41 45 2
44 42 46 1
45 43 47 1
46 44 48 1
47 46 49 1
48 46 50 2
49 47 51 1
50 48 52 1
51 48 53 1
52 49 54 1
53 49 55 1
54 51 56 1
55 51 57 2
56 52 58 1
57 53 59 2
58 54 60 1
59 58 61 2
60 58 62 1
61 60 63 2
62 60 64 1
63 61 65 1
64 62 66 2
65 63 67 1
66 64 68 2
67 65 69 2
68 67 70 2
69 69 71 1
70 10 13 1
71 53 55 1
72 66 69 1
73 68 70 1
74 32 72 1
75 72 73 1
76 72 74 2
77 33 75 1
78 75 76 1
79 76 77 1
80 76 78 2
BRACKET 1 32.2000 -23.5200 32.2000 -22.0500
1 34.7900 -22.0500 34.7900 -23.5200
1 3
ORIGINAL 1 79
REPEAT 1 80 81
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