Homo sapiens (human): 554
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Entry
554 CDS
T01001
Symbol
AVPR2, ADHR, DI1, DIR, DIR3, NDI, NDI1, V2R
Name
(RefSeq) arginine vasopressin receptor 2
KO
K04228
arginine vasopressin receptor 2
Organism
hsa
Homo sapiens (human)
Pathway
hsa04072
Phospholipase D signaling pathway
hsa04080
Neuroactive ligand-receptor interaction
hsa04962
Vasopressin-regulated water reabsorption
Network
nt06325
Hormone/cytokine signaling
Element
N00915
AVP-V2R-PKA signaling pathway
Disease
H00252
Congenital nephrogenic diabetes insipidus
H01294
Nephrogenic syndrome of inappropriate antidiuresis
H01682
Syndrome of inappropriate antidiuretic hormone secretion
H01683
Disorders of antidiuretic hormone (ADH) secretion
Drug target
Conivaptan (
DG00276
):
D01236
D07748
Desmopressin (
DG00497
):
D00291
D02235
<JP/US>
Lixivaptan:
D04752
Lypressin:
D00366
Mozavaptane hydrochloride:
D01855
Ornipressin:
D07227
Terlipressin (
DG00498
):
D06672
D08571
<US>
Tolvaptan (
DG03074
):
D01213
<JP/US>
D11659
<JP>
Vasopressin (Argipressin) (
DG00496
):
D00101
<JP/US>
D02983
D09820
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04072 Phospholipase D signaling pathway
554 (AVPR2)
09133 Signaling molecules and interaction
04080 Neuroactive ligand-receptor interaction
554 (AVPR2)
09150 Organismal Systems
09155 Excretory system
04962 Vasopressin-regulated water reabsorption
554 (AVPR2)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04030 G protein-coupled receptors [BR:
hsa04030
]
554 (AVPR2)
G protein-coupled receptors [BR:
hsa04030
]
Rhodopsin family
Peptide
Vasopressin
554 (AVPR2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
7tm_1
7TM_GPCR_Srsx
7TM_GPCR_Srv
7tm_4
Git3
Motif
Other DBs
NCBI-GeneID:
554
NCBI-ProteinID:
NP_000045
OMIM:
300538
HGNC:
897
Ensembl:
ENSG00000126895
Pharos:
P30518
(Tclin)
UniProt:
P30518
Structure
PDB
PDBj
LinkDB
All DBs
Position
X:153902625..153907166
Genome browser
AA seq
371 aa
AA seq
DB search
MLMASTTSAVPGHPSLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAVALSNGLVLA
ALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGPDALCRAVKYLQM
VGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFAQ
RNVEGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTLGIAACQVLIFREIHASLVPGP
SERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVVVYVLCWAPFFLVQLWAAWDPEA
PLEGAPFVLLMLLASLNSCTNPWIYASFSSSVSSELRSLLCCARGRTPPSLGPQDESCTT
ASSSLAKDTSS
NT seq
1116 nt
NT seq
+upstream
nt +downstream
nt
atgctcatggcgtccaccacttccgctgtgcctgggcatccctctctgcccagcctgccc
agcaacagcagccaggagaggccactggacacccgggacccgctgctagcccgggcggag
ctggcgctgctctccatagtctttgtggctgtggccctgagcaatggcctggtgctggcg
gccctagctcggcggggccggcggggccactgggcacccatacacgtcttcattggccac
ttgtgcctggccgacctggccgtggctctgttccaagtgctgccccagctggcctggaag
gccaccgaccgcttccgtgggccagatgccctgtgtcgggccgtgaagtatctgcagatg
gtgggcatgtatgcctcctcctacatgatcctggccatgacgctggaccgccaccgtgcc
atctgccgtcccatgctggcgtaccgccatggaagtggggctcactggaaccggccggtg
ctagtggcttgggccttctcgctccttctcagcctgccccagctcttcatcttcgcccag
cgcaacgtggaaggtggcagcggggtcactgactgctgggcctgctttgcggagccctgg
ggccgtcgcacctatgtcacctggattgccctgatggtgttcgtggcacctaccctgggt
atcgccgcctgccaggtgctcatcttccgggagattcatgccagtctggtgccagggcca
tcagagaggcctggggggcgccgcaggggacgccggacaggcagccccggtgagggagcc
cacgtgtcagcagctgtggccaagactgtgaggatgacgctagtgattgtggtcgtctat
gtgctgtgctgggcacccttcttcctggtgcagctgtgggccgcgtgggacccggaggca
cctctggaaggggcgccctttgtgctactcatgttgctggccagcctcaacagctgcacc
aacccctggatctatgcatctttcagcagcagcgtgtcctcagagctgcgaagcttgctc
tgctgtgcccggggacgcaccccacccagcctgggtccccaagatgagtcctgcaccacc
gccagctcctccctggccaaggacacttcatcgtga
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