| Entry |
|
|---|
| Name |
Levcromakalim (USAN/INN);
Lemakalim |
|---|
| Formula |
C16H18N2O3
|
|---|
| Exact mass |
286.1317
|
|---|
| Mol weight |
286.33
|
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| Structure |
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| Simcomp |
|
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| Class |
Cardiovascular agent
DG01583 ATP-sensitive potassium channel opener
|
|---|
| Remark |
|
|---|
| Efficacy |
Antiasthmatic, Antihypertensive |
|---|
| Target |
|
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| Pathway |
|
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| Structure map |
| map07232 | Potassium channel blocking and opening drugs |
|
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| Brite |
Drug groups [BR:br08330]
Cardiovascular agent
DG01583 ATP-sensitive potassium channel opener
D02385 Levcromakalim
Target-based classification of drugs [BR:br08310]
Transporters
ABC transporters
ABCC subfamily
ABCC8(SUR1)/KCNJ11(KIR6.2)
D02385 Levcromakalim (USAN/INN)
ABCC9(SUR2)/KCNJ11(KIR6.2)
D02385 Levcromakalim (USAN/INN)
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 21
1 O2x O 18.8220 -15.3856
2 C1z C 20.0267 -14.6877
3 C1y C 20.0267 -13.2917
4 C1y C 18.8220 -12.5938
5 N1y N 18.8237 -11.1979
6 C5x C 19.9576 -10.3721
7 C1x C 19.5280 -9.0438
8 C1x C 18.1321 -9.0421
9 C1x C 17.6990 -10.3692
10 O5x O 21.1921 -10.9896
11 C8y C 17.6101 -14.6877
12 C8y C 17.6101 -13.2917
13 C8x C 16.4012 -12.5938
14 C8y C 15.1922 -13.2917
15 C8x C 15.1922 -14.6877
16 C8x C 16.4012 -15.3856
17 C3b C 13.9836 -12.5938
18 N3a N 12.7850 -11.8747
19 C1a C 21.1894 -15.5709
20 C1a C 21.2734 -14.0291
21 O1a O 21.2360 -12.5481
BOND 23
1 4 12 1
2 6 10 2
3 4 5 1 #Up
4 11 1 1
5 1 2 1
6 2 3 1
7 3 4 1
8 11 12 1
9 12 13 2
10 13 14 1
11 14 15 2
12 15 16 1
13 16 11 2
14 5 6 1
15 14 17 1
16 6 7 1
17 17 18 3
18 7 8 1
19 2 19 1
20 8 9 1
21 2 20 1
22 9 5 1
23 3 21 1 #Down
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