Entry
Symbol
KCNJ11, KIR6.2
Name
potassium inwardly-rectifying channel subfamily J member 11
Pathway
Disease
H00409 Type 2 diabetes mellitus
H00410 Maturity onset diabetes of the young (MODY)
H00512 Permanent neonatal diabetes mellitus
H00513 Transient neonatal diabetes mellitus
H01267 Familial hyperinsulinemic hypoglycemia
Brite
KEGG Orthology (KO) [BR:ko00001 ]
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
K05004 KCNJ11, KIR6.2; potassium inwardly-rectifying channel subfamily J member 11
04929 GnRH secretion
K05004 KCNJ11, KIR6.2; potassium inwardly-rectifying channel subfamily J member 11
09160 Human Diseases
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
K05004 KCNJ11, KIR6.2; potassium inwardly-rectifying channel subfamily J member 11
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels
K05004 KCNJ11, KIR6.2; potassium inwardly-rectifying channel subfamily J member 11
Ion channels [BR:ko04040 ]
Voltage-gated cation channels
Potassium channel, inwardly-rectifying (Kir)
K05004 KCNJ11, KIR6.2; potassium inwardly-rectifying channel subfamily J member 11
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Genes
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Taxonomy UniProt
Reference
Authors
Tokuyama Y, Fan Z, Furuta H, Makielski JC, Polonsky KS, Bell GI, Yano H
Title
Rat inwardly rectifying potassium channel Kir6.2: cloning electrophysiological characterization, and decreased expression in pancreatic islets of male Zucker diabetic fatty rats.
Journal
Sequence
Reference
Authors
Inagaki N, Gonoi T, Clement JP 4th, Namba N, Inazawa J, Gonzalez G, Aguilar-Bryan L, Seino S, Bryan J
Title
Reconstitution of IKATP: an inward rectifier subunit plus the sulfonylurea receptor.
Journal
Sequence
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