Entry |
|
Name |
Reboxetine mesylate (USAN); Reboxetine mesilate; Vestra (TN) |
Formula |
C19H23NO3. CH4SO3
|
Exact mass |
409.1559
|
Mol weight |
409.50
|
Structure |
|
Simcomp |
|
Class |
Neuropsychiatric agent
DG03085 Selective norepinephrine reuptake inhibitor (NRI)
|
Remark |
|
Efficacy |
Antidepressant, Selective noradrenaline reuptake inhibitor (NRI) |
Target |
|
Pathway |
|
Interaction |
|
Structure map |
map07234 | Neurotransmitter transporter inhibitors |
|
Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N06 PSYCHOANALEPTICS
N06A ANTIDEPRESSANTS
N06AX Other antidepressants
N06AX18 Reboxetine
D02573 Reboxetine mesylate (USAN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG03085 Selective norepinephrine reuptake inhibitor (NRI)
DG00961 Reboxetine
D02573 Reboxetine mesylate
Target-based classification of drugs [BR:br08310]
Transporters
Solute carrier family
SLC6
SLC6A2 (NAT1)
D02573 Reboxetine mesylate (USAN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG03085 Selective norepinephrine reuptake inhibitor (NRI)
DG00961 Reboxetine
|
Other DBs |
|
LinkDB |
|
KCF data |
ATOM 28
1 C8x C 20.5327 -24.3754
2 C8x C 20.5327 -22.9740
3 C8y C 21.7501 -22.2697
4 C8x C 22.9607 -22.9740
5 C8x C 22.9607 -24.3754
6 C8x C 21.7501 -25.0726
7 C1c C 21.7520 -20.8682
8 C1y C 22.9674 -20.1725
9 O2a O 20.5381 -20.1694
10 C8y C 19.3226 -20.8651
11 O2x O 22.9635 -18.7772
12 C1x C 24.1792 -18.0744
13 C1x C 25.3929 -18.7802
14 N1x N 25.3911 -20.1816
15 C1x C 24.1756 -20.8773
16 C8x C 19.3223 -22.2633
17 C8x C 18.1138 -22.9661
18 C8x C 16.9000 -22.2602
19 C8x C 16.9017 -20.8587
20 C8y C 18.1173 -20.1630
21 O2a O 18.1209 -18.7616
22 C1b C 19.3304 -18.0604
23 C1a C 19.3340 -16.6590
24 C1a C 29.8429 -21.2133
25 S4a S 31.2374 -21.2133
26 O1d O 31.2303 -22.6078
27 O1d O 32.6318 -21.2133
28 O1d O 31.2303 -19.8189
BOND 29
1 12 13 1
2 13 14 1
3 14 15 1
4 15 8 1
5 7 3 1 #Up
6 7 8 1
7 1 2 2
8 7 9 1
9 10 16 2
10 16 17 1
11 17 18 2
12 18 19 1
13 19 20 2
14 20 10 1
15 2 3 1
16 20 21 1
17 9 10 1
18 21 22 1
19 3 4 2
20 22 23 1
21 4 5 1
22 5 6 2
23 6 1 1
24 8 11 1
25 11 12 1
26 24 25 1
27 25 26 2
28 25 27 1
29 25 28 2
|