Homo sapiens (human): 6530
Help
Entry
6530 CDS
T01001
Symbol
SLC6A2, NAT1, NET, NET1, SLC6A5
Name
(RefSeq) solute carrier family 6 member 2
KO
K05035
solute carrier family 6 (neurotransmitter transporter, noradrenalin) member 2
Organism
hsa
Homo sapiens (human)
Pathway
hsa04082
Neuroactive ligand signaling
hsa04721
Synaptic vesicle cycle
Network
nt06544
Neuroactive ligand signaling
Element
N01920
Transport of norepinephrine into neuron
Disease
H01031
Orthostatic intolerance
Drug target
Amezinium metilsulfate:
D01304
<JP>
Amfepramone (
DG00104
):
D03801
<US>
D07444
Amfetamine (
DG00966
):
D02074
<US>
D07445
<US>
Amitifadine (
DG01386
):
D10088
D10089
Amitriptyline (
DG00934
):
D00809
<JP/US>
D07448
Amitriptylinoxide:
D07449
Amoxapine:
D00228
<JP/US>
Amphetamine aspartate monohydrate:
D11622
Ampreloxetine (
DG03081
):
D11688
D11689
Atomoxetine (
DG00970
):
D02574
<JP/US>
D07473
Benzfetamine (
DG01755
):
D07514
D07515
<US>
Bupropion (
DG00957
):
D00817
<US>
D07591
D07938
<US>
Centanafadine (
DG01858
):
D10697
D10698
Cidoxepin hydrochloride:
D03491
Clomipramine (
DG00929
):
D00811
<JP/US>
D07727
Cocaine (
DG00808
):
D00110
D02182
<US>
Dasotraline (
DG01989
):
D10700
D10870
Desipramine (
DG00927
):
D00812
<US>
D07791
Desvenlafaxine (
DG00963
):
D02570
<US>
D07793
<US>
D11619
Dexamfetamine (
DG00967
):
D02078
<US>
D03740
<US>
Dexmethylphenidate (
DG00972
):
D03721
<US>
D07806
Dextroamphetamine saccharate:
D11623
Dosulepin (
DG00940
):
D01546
<JP>
D07872
Doxepin (
DG00937
):
D00814
<US>
D07875
Duloxetine (
DG00962
):
D01179
<JP/US>
D07880
Edivoxetine (
DG01310
):
D09890
D09891
Esreboxetine (
DG01309
):
D09340
D09341
Guanethidine (
DG00258
):
D02237
D04382
D08030
Hydroxyamphetamine hydrobromide:
D04473
Imipramine (
DG00928
):
D00815
<JP/US>
D08070
D08071
<US>
Imipraminoxide (
DG01542
):
D07334
D08072
Indeloxazine (
DG02869
):
D02170
D08077
Levomilnacipran (
DG01387
):
D10072
D10133
<US>
Liafensine:
D10443
Lisdexamfetamine (
DG00973
):
D04747
<JP/US>
D08130
Lofepramine (
DG00932
):
D01285
D08140
Lortalamine:
D04781
Maprotiline (
DG00941
):
D00818
<JP>
D02566
Mazindol:
D00367
<JP>
Metamfetamine (
DG00968
):
D02242
<JP/US>
D08187
Methylphenidate (
DG00969
):
D01296
<JP/US>
D04999
<US>
Midomafetamine (
DG03316
):
D11172
D12937
Milnacipran (
DG00960
):
D01107
<JP/US>
D08222
Napamezole hydrochloride:
D05119
Napitane mesylate:
D05120
Nisoxetine:
D05173
Nomifensine:
D05200
Nortriptyline (
DG00935
):
D00816
<JP/US>
D08288
Oxaprotiline hydrochloride:
D05284
Phendimetrazine (
DG01537
):
D02080
<US>
D08347
D08348
Phenmetrazine hydrochloride:
D05454
Phentermine (
DG00102
):
D05458
D05459
<US>
Protriptyline (
DG00936
):
D00484
<US>
D08447
Pyrovalerone hydrochloride:
D05663
Radafaxine hydrochloride:
D05692
Reboxetine (
DG00961
):
D02573
D08472
Sibutramine (
DG00108
):
D02571
D08513
Solriamfetol (
DG02989
):
D11315
D11328
<US>
Talopram hydrochloride:
D05997
Tampramine fumarate:
D02704
Tandamine hydrochloride:
D06004
Tapentadol (
DG00826
):
D06007
D10199
<US>
Tenamfetamine:
D12715
Toludesvenlafaxine (
DG03141
):
D11940
D11941
Trimipramine (
DG00931
):
D00394
D02408
<JP/US>
Venlafaxine (
DG00959
):
D00821
<JP/US>
D08670
D12403
<US>
Viloxazine (
DG00956
):
D02572
<US>
D08673
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09133 Signaling molecules and interaction
04082 Neuroactive ligand signaling
6530 (SLC6A2)
09150 Organismal Systems
09156 Nervous system
04721 Synaptic vesicle cycle
6530 (SLC6A2)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:
hsa02000
]
6530 (SLC6A2)
Transporters [BR:
hsa02000
]
Solute carrier family (SLC)
SLC6: Sodium- and chloride-dependent neurotransmitter transporter
6530 (SLC6A2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
SNF
Motif
Other DBs
NCBI-GeneID:
6530
NCBI-ProteinID:
NP_001034
OMIM:
163970
HGNC:
11048
Ensembl:
ENSG00000103546
UniProt:
P23975
Structure
PDB
PDBj
LinkDB
All DBs
Position
16:55655988..55706192
Genome browser
AA seq
617 aa
AA seq
DB search
MLLARMNPQVQPENNGADTGPEQPLRARKTAELLVVKERNGVQCLLAPRDGDAQPRETWG
KKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGAFLIPYTLFLIIAGMPLFYMELALGQYN
REGAATVWKICPFFKGVGYAVILIALYVGFYYNVIIAWSLYYLFSSFTLNLPWTDCGHTW
NSPNCTDPKLLNGSVLGNHTKYSKYKFTPAAEFYERGVLHLHESSGIHDIGLPQWQLLLC
LMVVVIVLYFSLWKGVKTSGKVVWITATLPYFVLFVLLVHGVTLPGASNGINAYLHIDFY
RLKEATVWIDAATQIFFSLGAGFGVLIAFASYNKFDNNCYRDALLTSSINCITSFVSGFA
IFSILGYMAHEHKVNIEDVATEGAGLVFILYPEAISTLSGSTFWAVVFFVMLLALGLDSS
MGGMEAVITGLADDFQVLKRHRKLFTFGVTFSTFLLALFCITKGGIYVLTLLDTFAAGTS
ILFAVLMEAIGVSWFYGVDRFSNDIQQMMGFRPGLYWRLCWKFVSPAFLLFVVVVSIINF
KPLTYDDYIFPPWANWVGWGIALSSMVLVPIYVIYKFLSTQGSLWERLAYGITPENEHHL
VAQRDIRQFQLQHWLAI
NT seq
1854 nt
NT seq
+upstream
nt +downstream
nt
atgcttctggcgcggatgaacccgcaggtgcagcccgagaacaacggggcggacacgggt
ccagagcagccccttcgggcgcgcaaaactgcggagctgctggtggtgaaggagcgcaac
ggcgtccagtgcctgctggcgccccgcgacggcgacgcgcagccccgggagacctggggc
aagaagatcgacttcctgctgtccgtagtcggcttcgcagtggacctggccaacgtgtgg
cgcttcccctacctctgctacaagaacggcggcggtgccttcttgatcccgtacacactg
ttccttatcatcgcggggatgcccctgttctacatggagctggctctgggacagtacaac
cgggagggggctgccaccgtttggaaaatctgcccattcttcaaaggcgttggctatgct
gtcatcctgatcgccctgtacgttggcttctactacaacgtcatcatcgcctggtcactc
tactacctcttctcctccttcaccctcaacctgccctggaccgactgtggccacacctgg
aacagccccaactgtaccgaccccaagctcctcaatggctccgtgcttggcaaccacacc
aagtactccaagtacaagttcacgccggcagccgagttttatgagcgtggtgtcctgcac
cttcacgagagcagcgggattcatgacatcggcctgccccagtggcagctcttgctctgt
ctgatggtcgtcgtcatcgtcttgtattttagcctctggaaaggggtgaagacatcagga
aaggtggtgtggatcacagccacgctgccttacttcgtgctgttcgtgctcctggtccat
ggcgtcacgctgcccggagcctccaatggcatcaatgcctacctgcacatcgacttctac
cgcttgaaagaggccacggtatggattgatgccgcaactcagatatttttttccttgggg
gctggatttggagtattgattgcatttgccagttacaacaaatttgacaacaactgttac
agggatgccctgctgaccagcagcatcaactgtatcaccagcttcgtctctgggttcgcc
atcttctccatccttggttacatggcccatgaacacaaggtcaacattgaggatgtggcc
acagaaggagctggcctagtgttcatcctgtatccagaggccatttctaccctgtctgga
tctacattctgggctgttgtgtttttcgtcatgctcctggcgctgggccttgacagctca
atgggaggcatggaggctgtcatcacgggcctggcagatgacttccaggtcctgaagcga
caccggaaactcttcacatttggcgtcaccttcagcactttccttctcgccctgttctgc
ataaccaagggtggaatttacgtcttgaccctcctggacacctttgctgcgggcacctcc
atcctttttgctgtcctcatggaagccatcggagtttcctggttttatggagtggacagg
ttcagcaacgacatccagcagatgatggggttcaggccgggtctatactggagactgtgc
tggaagttcgtcagtcctgccttcctcctgttcgtggttgtggtcagcatcatcaacttc
aagccactcacctacgacgactacatcttcccgccctgggccaactgggtggggtggggc
atcgccctgtcctccatggtcctggtgcccatctacgtcatctataagttcctcagcacg
cagggctctctttgggagagactggcctatggcatcacgccagagaacgagcaccacctg
gtggctcagagggacatcagacagttccagttgcaacactggctggccatctga
DBGET
integrated database retrieval system
