KEGG   DRUG: Becaplermin
Entry
D03065                      Drug                                   
Name
Becaplermin (USAN/INN);
Regranex (TN)
Product
REGRANEX (Smith & Nephew)
Sequence
SLGSLTIAEP AMIAECKTRT EVFEISRRLI DRTNANFLVW PPCVEVQRCS GCCNNRNVQC
RPTQVQLRPV QVRKIEIVRK KPIFKKATVT LEDHLACKCE TVAAARPVT
  Type
Peptide
Remark
ATC code: A01AD08 D03AX06
Product: D03065<US>
Efficacy
Anti-ulcerative (skin)
  Disease
Diabetic neuropathic ulcers [DS:H01459]
Comment
recombinant platelet-derived growth factor BB (PDGF-BB)
Target
PDGFRB [HSA:5159] [KO:K05089]
  Pathway
hsa04010  MAPK signaling pathway
hsa04510  Focal adhesion
hsa04540  Gap junction
hsa04810  Regulation of actin cytoskeleton
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A01 STOMATOLOGICAL PREPARATIONS
   A01A STOMATOLOGICAL PREPARATIONS
    A01AD Other agents for local oral treatment
     A01AD08 Becaplermin
      D03065  Becaplermin (USAN/INN) <US>
 D DERMATOLOGICALS
  D03 PREPARATIONS FOR TREATMENT OF WOUNDS AND ULCERS
   D03A CICATRIZANTS
    D03AX Other cicatrizants
     D03AX06 Becaplermin
      D03065  Becaplermin (USAN/INN) <US>
USP drug classification [BR:br08302]
 Dermatological Agents
  Dermatological Agents, Other
   Wound Care Agents
    Becaplermin
     D03065  Becaplermin (USAN/INN)
Target-based classification of drugs [BR:br08310]
 Protein kinases
  Receptor tyrosine kinases (RTK)
   PDGFR family
    PDGFRB
     D03065  Becaplermin (USAN/INN) <US>
Other DBs
CAS: 165101-51-9
PubChem: 17397220
LinkDB

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