KEGG   ORTHOLOGY: K05089
Entry
K05089                      KO                                     

Symbol
PDGFRB, CD140B
Name
platelet-derived growth factor receptor beta [EC:2.7.10.1]
Pathway
map01521  EGFR tyrosine kinase inhibitor resistance
map04010  MAPK signaling pathway
map04014  Ras signaling pathway
map04015  Rap1 signaling pathway
map04020  Calcium signaling pathway
map04072  Phospholipase D signaling pathway
map04151  PI3K-Akt signaling pathway
map04510  Focal adhesion
map04540  Gap junction
map04630  JAK-STAT signaling pathway
map04810  Regulation of actin cytoskeleton
map05165  Human papillomavirus infection
map05200  Pathways in cancer
map05206  MicroRNAs in cancer
map05214  Glioma
map05215  Prostate cancer
map05218  Melanoma
map05230  Central carbon metabolism in cancer
map05231  Choline metabolism in cancer
Disease
H00042  Glioma
H01574  Familial idiopathic basal ganglia calcification
H01910  Infantile myofibromatosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K05089  PDGFRB, CD140B; platelet-derived growth factor receptor beta
   04014 Ras signaling pathway
    K05089  PDGFRB, CD140B; platelet-derived growth factor receptor beta
   04015 Rap1 signaling pathway
    K05089  PDGFRB, CD140B; platelet-derived growth factor receptor beta
   04630 JAK-STAT signaling pathway
    K05089  PDGFRB, CD140B; platelet-derived growth factor receptor beta
   04020 Calcium signaling pathway
    K05089  PDGFRB, CD140B; platelet-derived growth factor receptor beta
   04072 Phospholipase D signaling pathway
    K05089  PDGFRB, CD140B; platelet-derived growth factor receptor beta
   04151 PI3K-Akt signaling pathway
    K05089  PDGFRB, CD140B; platelet-derived growth factor receptor beta
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K05089  PDGFRB, CD140B; platelet-derived growth factor receptor beta
   04540 Gap junction
    K05089  PDGFRB, CD140B; platelet-derived growth factor receptor beta
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K05089  PDGFRB, CD140B; platelet-derived growth factor receptor beta
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05089  PDGFRB, CD140B; platelet-derived growth factor receptor beta
   05206 MicroRNAs in cancer
    K05089  PDGFRB, CD140B; platelet-derived growth factor receptor beta
   05230 Central carbon metabolism in cancer
    K05089  PDGFRB, CD140B; platelet-derived growth factor receptor beta
   05231 Choline metabolism in cancer
    K05089  PDGFRB, CD140B; platelet-derived growth factor receptor beta
  09162 Cancer: specific types
   05214 Glioma
    K05089  PDGFRB, CD140B; platelet-derived growth factor receptor beta
   05218 Melanoma
    K05089  PDGFRB, CD140B; platelet-derived growth factor receptor beta
   05215 Prostate cancer
    K05089  PDGFRB, CD140B; platelet-derived growth factor receptor beta
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    K05089  PDGFRB, CD140B; platelet-derived growth factor receptor beta
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    K05089  PDGFRB, CD140B; platelet-derived growth factor receptor beta
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K05089  PDGFRB, CD140B; platelet-derived growth factor receptor beta
  09183 Protein families: signaling and cellular processes
   04090 CD molecules
    K05089  PDGFRB, CD140B; platelet-derived growth factor receptor beta
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     K05089  PDGFRB, CD140B; platelet-derived growth factor receptor beta
Protein kinases [BR:ko01001]
 Receptor tyrosine kinases (RTK)
  PDGFR family [OT]
   K05089  PDGFRB, CD140B; platelet-derived growth factor receptor beta
CD molecules [BR:ko04090]
 Proteins
  K05089  CD140b, PDGFRB; platelet-derived growth factor receptor, beta polypeptide
Other DBs
GO: 0004992
Genes
HSA: 5159(PDGFRB)
PTR: 462188(PDGFRB)
PPS: 100975853(PDGFRB)
GGO: 101150577(PDGFRB)
PON: 100460001(PDGFRB)
NLE: 100597894(PDGFRB)
MCC: 711353(PDGFRB)
MCF: 101867161(PDGFRB)
CSAB: 103244790(PDGFRB)
CATY: 105589876(PDGFRB)
PANU: 101008264(PDGFRB)
RRO: 104670408(PDGFRB)
RBB: 108532047(PDGFRB)
TFN: 117065596(PDGFRB)
PTEH: 111552670(PDGFRB)
CJC: 100389852(PDGFRB)
SBQ: 101040158(PDGFRB)
MMUR: 105858450(PDGFRB)
MMU: 18596(Pdgfrb)
MCAL: 110284880(Pdgfrb)
MPAH: 110333065(Pdgfrb)
RNO: 24629(Pdgfrb)
MCOC: 116087226(Pdgfrb)
MUN: 110546695(Pdgfrb)
CGE: 100764374(Pdgfrb)
PLEU: 114707365(Pdgfrb)
NGI: 103747076(Pdgfrb)
HGL: 101721151(Pdgfrb)
CPOC: 100726506(Pdgfrb)
CCAN: 109685664(Pdgfrb)
OCU: 100342872(PDGFRB)
OPI: 101516431(PDGFRB)
TUP: 102492413(PDGFRB)
CFA: 442985(PDGFRB)
VVP: 112927357(PDGFRB)
VLG: 121486777(PDGFRB)
AML: 100472005(PDGFRB)
UMR: 103664600(PDGFRB)
UAH: 113263944(PDGFRB)
ORO: 101374793(PDGFRB)
ELK: 111140848
MPUF: 101684361(PDGFRB)
EJU: 114211916(PDGFRB)
FCA: 101084600(PDGFRB)
PYU: 121045013(PDGFRB)
PBG: 122493456(PDGFRB)
PTG: 102954207(PDGFRB)
PPAD: 109275948(PDGFRB)
AJU: 106985388(PDGFRB)
HHV: 120236611(PDGFRB)
BTA: 527165(PDGFRB)
BOM: 102270608(PDGFRB)
BIU: 109562197(PDGFRB)
BBUB: 102392216(PDGFRB)
CHX: 102184426(PDGFRB)
OAS: 101122783(PDGFRB)
ODA: 120863403(PDGFRB)
CCAD: 122439706(PDGFRB)
SSC: 102166564(PDGFRB)
CFR: 102512951(PDGFRB)
CBAI: 105074292(PDGFRB)
CDK: 105098486(PDGFRB)
BACU: 103019883(PDGFRB)
LVE: 103082363(PDGFRB)
OOR: 101272795(PDGFRB)
DLE: 111183086(PDGFRB)
PCAD: 102995915(PDGFRB)
PSIU: 116751332(PDGFRB)
ECB: 100071665(PDGFRB)
EPZ: 103549125(PDGFRB)
EAI: 106838493(PDGFRB)
MYB: 102241145(PDGFRB)
MYD: 102764172(PDGFRB)
MMYO: 118658697(PDGFRB)
MLF: 102441579(PDGFRB)
MNA: 107535230(PDGFRB)
PKL: 118711223(PDGFRB)
HAI: 109375002(PDGFRB)
DRO: 112319577(PDGFRB)
SHON: 118986157(PDGFRB)
AJM: 119061365(PDGFRB)
PDIC: 114509632(PDGFRB)
MMF: 118615300(PDGFRB)
RFQ: 117016666(PDGFRB)
PALE: 102887643(PDGFRB)
PGIG: 120581545(PDGFRB)
RAY: 107497163(PDGFRB)
MJV: 108385397(PDGFRB)
TOD: 119243270(PDGFRB)
LAV: 100671240(PDGFRB)
TMU: 101360003
MDO: 100028943(PDGFRB)
GAS: 123233823(PDGFRB)
SHR: 100917212(PDGFRB)
PCW: 110192821(PDGFRB)
OAA: 100079459(PDGFRB)
GGA: 770488(PDGFRB)
PCOC: 116232153(PDGFRB)
MGP: 100550611(PDGFRB)
CJO: 107320191(PDGFRB)
NMEL: 110405265(PDGFRB)
APLA: 101799587(PDGFRB)
ACYG: 106032823(PDGFRB)
TGU: 100223375(PDGFRB)
LSR: 110482721(PDGFRB)
SCAN: 103817301(PDGFRB)
PMOA: 120498517(PDGFRB)
OTC: 121332255(PDGFRB)
PRUF: 121361297(PDGFRB)
GFR: 102045343(PDGFRB)
FAB: 101809926(PDGFRB)
PHI: 102111524(PDGFRB)
PMAJ: 107210844(PDGFRB)
CCAE: 111935543(PDGFRB)
CCW: 104689579(PDGFRB)
ETL: 114063193(PDGFRB)
FPG: 101918438(PDGFRB)
FCH: 102052718(PDGFRB)
CLV: 102096790(PDGFRB)
EGZ: 104123312(PDGFRB)
NNI: 104014196(PDGFRB)
ACUN: 113485173(PDGFRB)
PADL: 103915745(PDGFRB)
AAM: 106493441(PDGFRB)
AROW: 112964785(PDGFRB)
NPD: 112954304(PDGFRB)
DNE: 112996927(PDGFRB)
ASN: 102372962(PDGFRB)
AMJ: 102566175(PDGFRB)
CPOO: 109310161(PDGFRB)
GGN: 109289892(PDGFRB)
PSS: 102460895(PDGFRB)
CMY: 102944650(PDGFRB)
CPIC: 101940553(PDGFRB)
CABI: 116819978(PDGFRB)
MRV: 120369946(PDGFRB)
ACS: 100555784(pdgfrb)
PVT: 110086089(PDGFRB)
SUND: 121923103(PDGFRB)
PBI: 103051588(PDGFRB)
PMUR: 107294993
TSR: 106547766(PDGFRB)
PGUT: 117655249(PDGFRB)
VKO: 123035769(PDGFRB)
PMUA: 114591343(PDGFRB)
ZVI: 118080419(PDGFRB)
XLA: 108712643(pdgfrb.S)
XTR: 100487523(pdgfrb)
NPR: 108785807(PDGFRB)
DRE: 559529(pdgfrb)
IPU: 108274697(pdgfrb)
PHYP: 113529620(pdgfrb)
AMEX: 103036483
EEE: 113575581(pdgfrb)
TRU: 101061130 101074724(pdgfrb)
NCC: 104965701(pdgfrb)
CGOB: 115014733(pdgfrb) 115019444
ELY: 117260792(pdgfrb) 117270921
PLEP: 121939111 121947843(pdgfrb)
SLUC: 116062368 116064307(pdgfrb)
ECRA: 117951210(pdgfrb)
PFLV: 114562615(pdgfrb) 114566403
GAT: 120817382(pdgfrb)
PPUG: 119210567(pdgfrb)
CUD: 121516062(pdgfrb) 121519179
MZE: 101466822 101484671(pdgfrb)
ONL: 100695603(pdgfrb) 100709470
OAU: 116329079(pdgfrb) 116329738
OLA: 101155039(pdgfrb) 101156428
OML: 112136844 112153320(pdgfrb)
XMA: 102229755 102233464(pdgfrb)
XCO: 114139478(pdgfrb) 114153115
XHE: 116713960(pdgfrb) 116728444
PRET: 103459902 103471279(pdgfrb)
GAF: 122837604(pdgfrb) 122844817
CVG: 107095000(pdgfrb) 107102292
CTUL: 119777911(pdgfrb) 119785587
NFU: 107375657(pdgfrb)
KMR: 108228837 108240544(pdgfrb)
ALIM: 106517359(pdgfrb) 106532997
AOCE: 111569523(pdgfrb) 111575719
CSEM: 103391002(pdgfrb) 103392104
POV: 109626437(pdgfrb)
SSEN: 122762812 122778422(pdgfrb)
HHIP: 117769118(pdgfrb)
LCF: 108873646 108899186(pdgfrb)
SDU: 111226471(pdgfrb) 111239485
SLAL: 111646633(pdgfrb) 111671142
XGL: 120785203(pdgfrb) 120802843
HCQ: 109518748(pdgfrb) 109528881
SFM: 108936824(pdgfrb)
PKI: 111855164(pdgfrb)
AANG: 118223372(pdgfrb) 118234934
LOC: 102697036(pdgfrb)
PSPA: 121297330(pdgfrb) 121324756
ARUT: 117413283(pdgfrb)
LCM: 102361386(PDGFRB)
CMK: 103188232
ATEN: 116297063
 » show all
Reference
  Authors
Jones AV, Cross NC
  Title
Oncogenic derivatives of platelet-derived growth factor receptors.
  Journal
Cell Mol Life Sci 61:2912-23 (2004)
DOI:10.1007/s00018-004-4272-z
Reference
PMID:2835772
  Authors
Gronwald RG, Grant FJ, Haldeman BA, Hart CE, O'Hara PJ, Hagen FS, Ross R, Bowen-Pope DF, Murray MJ
  Title
Cloning and expression of a cDNA coding for the human platelet-derived growth factor receptor: evidence for more than one receptor class.
  Journal
Proc Natl Acad Sci U S A 85:3435-9 (1988)
DOI:10.1073/pnas.85.10.3435
  Sequence
[hsa:5159]
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