KEGG   DRUG: Bivalirudin
Entry
D03136                      Drug                                   

Name
Bivalirudin (USAN/INN)
Formula
C98H138N24O33
Exact mass
2178.9858
Mol weight
2180.2853
Sequence
FPRPGGGGNG DFEEIPEEYL
  Type
Peptide
Class
Cardiovascular agent
 DG01511  Thrombin inhibitor
 DG01950  Antithrombotic agent
  DG01511  Thrombin inhibitor
Remark
ATC code: B01AE06
Chemical structure group: DG02963
Product (DG02963): D11280<US>
Efficacy
Anticoagulant, Thrombin inhibitor
Comment
Peptide
Hirudin derivative
Target
F2 [HSA:2147] [KO:K01313]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04610  Complement and coagulation cascades
Interaction
Structure map
map07049  Antithrombosis agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 B BLOOD AND BLOOD FORMING ORGANS
  B01 ANTITHROMBOTIC AGENTS
   B01A ANTITHROMBOTIC AGENTS
    B01AE Direct thrombin inhibitors
     B01AE06 Bivalirudin
      D03136  Bivalirudin (USAN/INN)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Hydrolases (EC3)
   Serine peptidases
    F2
     D03136  Bivalirudin (USAN/INN)
New drug approvals in the USA [br08319.html]
 New molecular entities and new therapeutic biological products
  D03136
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D03136
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D03136
Other DBs
CAS: 128270-60-0
PubChem: 17397290
DrugBank: DB00006
LinkDB

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