KEGG   COMPOUND: C00752
Entry
C00752                      Compound                               
Name
Thrombin;
Coagulation factor IIa
Sequence
(A chain)
TFGSGEADCG LRPLFEKKSL EDKTERELLE SYIDGR
(B chain)
VEGSDAEIG MSPWQVMLFR KSPQELLCGA SLISDRWVLT AAHCLLYPPW DKNFTENDLL
VRIGKHSRTR YERNIEKISM LEKIYIHPRY NWRENLDRDI ALMKLKKPVA FSDYIHPVCL
PDRETAASLL QAGYKGRVTG WGNLKETWTA NVGKGQPSVL QVVNLPIVER PVCKDSTRIR
ITDNMFCAGY KPDEGKRGDA CEGDSGGPFV MKSPFNNRWY QMGIVSWGEG CDRDGKYGFY
THVFRLKKWI QKVIDQFGE
(Disulfide bridge: A9-B119)
  Organism
Homo sapiens [HSA:2147]
  Type
Peptide
Remark
Same as: D00090
Comment
active form [EC:3.4.21.5] of prothrombin [KO:K01313]
Pathway
map04610  Complement and coagulation cascades
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 B BLOOD AND BLOOD FORMING ORGANS
  B02 ANTIHEMORRHAGICS
   B02B VITAMIN K AND OTHER HEMOSTATICS
    B02BC Local hemostatics
     B02BC06 Thrombin
      D00090  Thrombin (JP18/USP/INN) <JP/US>
    B02BD Blood coagulation factors
     B02BD30 Thrombin
      D00090  Thrombin (JP18/USP/INN) <JP/US>
Therapeutic category of drugs in Japan [BR:br08301]
 3  Agents affecting metabolism
  33  Blood and body fluid agents
   332  Hemostatics
    3323  Hemostatics for organs
     D00090  Thrombin (JP18/USP/INN)
Drug groups [BR:br08330]
 Blood modifier agent
  DG02016  Hemostatics
   DG02014  Blood coagulation accelerant
    DG00169  Thrombin
     D00090  Thrombin
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00090  Thrombin
Other DBs
CAS: 9002-04-4
PubChem: 4014
ChEBI: 9574
NIKKAJI: J247.643F
LinkDB

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