| Entry |
|
|---|
| Name |
Chlorothiazide sodium (USP);
Diuril (TN) |
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| Product |
|
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| Generic |
|
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| Formula |
C7H5ClN3O4S2. Na
|
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| Exact mass |
316.9308
|
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| Mol weight |
317.71
|
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| Structure |
|
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| Simcomp |
|
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| Class |
|
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| Remark |
| Product (DG00268): | D00519<US> D03471<US> |
|
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| Efficacy |
Antihypertensive, Diuretic |
|---|
| Disease |
Nephrotic syndrome [DS: H01657] |
|---|
| Target |
|
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| Interaction |
|
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| Structure map |
| map07017 | Sulfonamide derivatives - diuretics |
| map07055 | Sulfonamide derivatives - overview |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C03 DIURETICS
C03A LOW-CEILING DIURETICS, THIAZIDES
C03AA Thiazides, plain
C03AA04 Chlorothiazide
D03471 Chlorothiazide sodium (USP) <US>
USP drug classification [BR:br08302]
Cardiovascular Agents
Diuretics, Thiazide
Chlorothiazide
D03471 Chlorothiazide sodium (USP)
Drug groups [BR:br08330]
Cardiovascular agent
DG03231 Antihypertensive
DG01749 Thiazide diuretic
DG00268 Chlorothiazide
D03471 Chlorothiazide sodium
DG01690 Sulfonamide diuretic
DG01749 Thiazide diuretic
DG00268 Chlorothiazide
D03471 Chlorothiazide sodium
Drug classes [BR:br08332]
Cardiovascular agent
DG03231 Antihypertensive
D03471 Chlorothiazide sodium
Target-based classification of drugs [BR:br08310]
Transporters
Solute carrier family
SLC12
SLC12A3 (TSC)
D03471 Chlorothiazide sodium (USP) <US>
Drug groups [BR:br08330]
Cardiovascular agent
DG03231 Antihypertensive
DG01749 Thiazide diuretic
DG00268 Chlorothiazide
DG01690 Sulfonamide diuretic
DG01749 Thiazide diuretic
DG00268 Chlorothiazide
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 18
1 C8y C 19.8888 -15.0612
2 C8y C 19.8945 -16.4185
3 C8x C 21.0647 -14.3768
4 S2x S 18.7069 -14.3943
5 C8x C 21.0704 -17.0913
6 N5x N 18.7303 -17.1087
7 C8y C 22.2406 -15.0495
8 N4x N 17.5370 -15.0846 #-
9 O3c O 17.3848 -13.5811
10 O3c O 19.9297 -13.5577
11 C8y C 22.2464 -16.4068
12 C8x C 17.5487 -16.4418
13 S4a S 23.4165 -14.3651
14 X Cl 23.4282 -17.0796
15 N1a N 24.6567 -13.5168
16 O3c O 24.5456 -15.3714
17 O3c O 22.3283 -13.3295
18 Z Na 14.0700 -15.1900 #+
BOND 18
1 1 2 2
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 2
7 4 8 1
8 4 9 2
9 4 10 2
10 5 11 2
11 6 12 2
12 7 13 1
13 11 14 1
14 13 15 1
15 13 16 2
16 13 17 2
17 7 11 1
18 8 12 1
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