| Entry |
|
|---|
| Name |
Dextromethorphan polistirex (USAN);
Delsym (TN) |
|---|
| Class |
Neuropsychiatric agent
DG01498 NMDA receptor antagonist
Metabolizing enzyme substrate
DG01644 CYP2D6 substrate
|
|---|
| Remark |
| Product (DG01078): | D00848<JP> |
| Product (mixture): | D11647<US> |
|
|---|
| Efficacy |
Antitussive |
|---|
| Comment |
Opium alkaloid, morphinan, nonnarcotic
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Metabolism |
Enzyme: CYP2D6 [HSA: 1565]
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07235 | N-Methyl-D-aspartic acid (NMDA) receptor antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
R RESPIRATORY SYSTEM
R05 COUGH AND COLD PREPARATIONS
R05D COUGH SUPPRESSANTS, EXCL. COMBINATIONS WITH EXPECTORANTS
R05DA Opium alkaloids and derivatives
R05DA09 Dextromethorphan
D03744 Dextromethorphan polistirex (USAN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01498 NMDA receptor antagonist
DG01078 Dextromethorphan
D03744 Dextromethorphan polistirex
Metabolizing enzyme substrate
DG01644 CYP2D6 substrate
DG01078 Dextromethorphan
D03744 Dextromethorphan polistirex
Target-based classification of drugs [BR:br08310]
Ion channels
Ligand-gated ion channels
Glutamate (ionotropic), NMDA
GRIN (NMDAR)
D03744 Dextromethorphan polistirex (USAN)
Transporters
Other transporters
Auxiliary transport proteins (TC:8.A)
SIGMAR1
D03744 Dextromethorphan polistirex (USAN)
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D03744
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01498 NMDA receptor antagonist
DG01078 Dextromethorphan
Metabolizing enzyme substrate
DG01644 CYP2D6 substrate
DG01078 Dextromethorphan
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
