| Entry |
|
|---|
| Name |
Quinapril (INN) |
|---|
| Formula |
C25H30N2O5
|
|---|
| Exact mass |
438.2155
|
|---|
| Mol weight |
438.52
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG01925 Renin-angiotensin system inhibitor
DG01501 Angiotensin-converting enzyme inhibitor
DG03231 Antihypertensive
DG01501 Angiotensin-converting enzyme inhibitor
|
|---|
| Remark |
| Product (DG00338): | D00459<US> |
|
|---|
| Efficacy |
Antihypertensive, Angiotensin-converting enzyme inhibitor |
|---|
| Comment |
Active form of prodrug: Quinaprilat [DR: D03773]
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07217 | Renin-angiotensin system inhibitors |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C09 AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM
C09A ACE INHIBITORS, PLAIN
C09AA ACE inhibitors, plain
C09AA06 Quinapril
D03752 Quinapril (INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01925 Renin-angiotensin system inhibitor
DG01501 Angiotensin-converting enzyme inhibitor
DG00338 Quinapril
D03752 Quinapril
DG03231 Antihypertensive
DG01501 Angiotensin-converting enzyme inhibitor
DG00338 Quinapril
D03752 Quinapril
Target-based classification of drugs [BR:br08310]
Enzymes
Hydrolases (EC3)
Peptidyl-dipeptidases
ACE (CD143)
D03752 Quinapril (INN)
Prodrugs [br08324.html]
D03752
Drug groups [BR:br08330]
Cardiovascular agent
DG01925 Renin-angiotensin system inhibitor
DG01501 Angiotensin-converting enzyme inhibitor
DG00338 Quinapril
DG03231 Antihypertensive
DG01501 Angiotensin-converting enzyme inhibitor
DG00338 Quinapril
Prodrugs [br08324.html]
DG00338
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 32
1 C1x C 38.2900 -20.0200
2 C8y C 39.4800 -19.3200
3 N1y N 37.1000 -19.3200
4 C8y C 39.4800 -17.9200
5 C8x C 40.7400 -20.0200
6 C1y C 37.1000 -17.9200
7 C1x C 38.2900 -17.2200
8 C8x C 40.7400 -17.2200
9 C8x C 41.9300 -19.3200
10 C8x C 41.9300 -17.9200
11 N1b N 33.4600 -20.0200
12 C1c C 32.2700 -19.3200
13 C7a C 32.2700 -17.9200
14 C1b C 31.0100 -20.0200
15 O7a O 33.4600 -17.2200
16 O6a O 31.0100 -17.2200
17 C1b C 29.8200 -19.3200
18 C1b C 33.4600 -15.8200
19 C8y C 28.6300 -20.0200
20 C1a C 32.2000 -15.1200
21 C8x C 28.6300 -21.4200
22 C8x C 27.3700 -19.3200
23 C8x C 27.3700 -22.1200
24 C8x C 26.1800 -20.0200
25 C8x C 26.1800 -21.4200
26 C1c C 34.6500 -19.3200
27 C5a C 35.8400 -20.0200
28 O5a O 35.8400 -21.4200
29 C1a C 34.6500 -17.9200
30 C6a C 37.1000 -16.5200
31 O6a O 38.2900 -15.7500
32 O6a O 35.8400 -15.8200
BOND 34
1 6 7 1
2 9 10 1
3 1 2 1
4 1 3 1
5 11 12 1
6 12 13 1 #Up
7 12 14 1
8 13 15 1
9 13 16 2
10 14 17 1
11 15 18 1
12 17 19 1
13 18 20 1
14 19 21 1
15 19 22 2
16 21 23 2
17 22 24 1
18 23 25 1
19 24 25 2
20 2 4 2
21 11 26 1
22 2 5 1
23 26 27 1
24 27 3 1
25 3 6 1
26 27 28 2
27 4 7 1
28 26 29 1 #Up
29 4 8 1
30 6 30 1 #Down
31 5 9 2
32 30 31 1
33 8 10 2
34 30 32 2
|
|---|
