| Entry |
|
|---|
| Name |
Libenzapril (USAN/INN) |
|---|
| Formula |
C18H25N3O5
|
|---|
| Exact mass |
363.1794
|
|---|
| Mol weight |
363.41
|
|---|
| Structure |
|
|---|
| Class |
Cardiovascular agent
DG01925 Renin-angiotensin system inhibitor
DG01501 Angiotensin-converting enzyme inhibitor
DG03231 Antihypertensive
DG01501 Angiotensin-converting enzyme inhibitor
|
|---|
| Efficacy |
Antihypertensive, Angiotensin-converting enzyme inhibitor |
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Brite |
Drug groups [BR:br08330]
Cardiovascular agent
DG01925 Renin-angiotensin system inhibitor
DG01501 Angiotensin-converting enzyme inhibitor
D03758 Libenzapril
DG03231 Antihypertensive
DG01501 Angiotensin-converting enzyme inhibitor
D03758 Libenzapril
Target-based classification of drugs [BR:br08310]
Peptidases and inhibitors
Metallo peptidases
Family M2
ACE (CD143)
D03758 Libenzapril (USAN/INN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 26
1 C1y C 33.6000 -16.6600
2 C5x C 34.4400 -17.7100
3 C1x C 33.8100 -15.2600
4 N1y N 35.8400 -17.7100
5 C1x C 35.0700 -14.6300
6 C8y C 36.6800 -16.5900
7 C8y C 36.4000 -15.1900
8 C8x C 38.0800 -16.9400
9 C8x C 39.0600 -16.0300
10 C8x C 38.7100 -14.6300
11 C8x C 37.3800 -14.2100
12 O5x O 33.7400 -18.9700
13 C1b C 36.5400 -18.9000
14 C6a C 37.9400 -18.9000
15 O6a O 38.6400 -20.0900
16 O6a O 38.6400 -17.7100
17 C6a C 31.1500 -15.1900
18 C1c C 31.1500 -16.5900
19 N1b N 32.3400 -17.3600
20 O6a O 29.9600 -14.4900
21 C1b C 29.9600 -17.2900
22 C1b C 28.7700 -16.5900
23 C1b C 27.5100 -17.2900
24 C1b C 26.3200 -16.5200
25 N1a N 25.1300 -17.2200
26 O6a O 32.4100 -14.5600
BOND 27
1 1 2 1
2 1 3 1
3 2 4 1
4 3 5 1
5 4 6 1
6 5 7 1
7 6 7 1
8 6 8 2
9 8 9 1
10 9 10 2
11 10 11 1
12 7 11 2
13 2 12 2
14 4 13 1
15 13 14 1
16 14 15 1
17 14 16 2
18 17 18 1
19 18 19 1
20 1 19 1 #Up
21 17 20 1
22 18 21 1 #Up
23 21 22 1
24 22 23 1
25 23 24 1
26 24 25 1
27 17 26 2
|
|---|
