| Entry |
|
|---|
| Name |
Spirapril hydrochloride (USAN);
Renormax (TN) |
|---|
| Formula |
C22H30N2O5S2. HCl
|
|---|
| Exact mass |
502.1363
|
|---|
| Mol weight |
503.08
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG01925 Renin-angiotensin system inhibitor
DG01501 Angiotensin-converting enzyme inhibitor
DG03231 Antihypertensive
DG01501 Angiotensin-converting enzyme inhibitor
|
|---|
| Remark |
|
|---|
| Efficacy |
Antihypertensive, Angiotensin-converting enzyme inhibitor |
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C09 AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM
C09A ACE INHIBITORS, PLAIN
C09AA ACE inhibitors, plain
C09AA11 Spirapril
D03765 Spirapril hydrochloride (USAN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01925 Renin-angiotensin system inhibitor
DG01501 Angiotensin-converting enzyme inhibitor
DG00342 Spirapril
D03765 Spirapril hydrochloride
DG03231 Antihypertensive
DG01501 Angiotensin-converting enzyme inhibitor
DG00342 Spirapril
D03765 Spirapril hydrochloride
Target-based classification of drugs [BR:br08310]
Enzymes
Hydrolases (EC3)
Peptidyl-dipeptidases
ACE (CD143)
D03765 Spirapril hydrochloride (USAN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01925 Renin-angiotensin system inhibitor
DG01501 Angiotensin-converting enzyme inhibitor
DG00342 Spirapril
DG03231 Antihypertensive
DG01501 Angiotensin-converting enzyme inhibitor
DG00342 Spirapril
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 32
1 N1y N 33.3340 -17.8513
2 C5a C 32.1482 -18.5488
3 C1c C 30.9623 -17.8513
4 O5a O 32.1482 -19.9439
5 N1b N 29.7067 -18.5488
6 C1a C 30.9623 -16.4562
7 C1c C 28.5209 -17.8513
8 C7a C 28.5209 -16.4562
9 C1b C 27.3351 -18.5488
10 O7a O 29.7067 -15.7586
11 O6a O 27.3351 -15.7586
12 C1b C 26.0795 -17.8513
13 C1b C 29.7067 -14.3635
14 C8y C 24.8936 -18.5488
15 C1a C 28.5209 -13.6659
16 C1y C 33.3340 -16.4513
17 C1x C 34.6655 -18.2839
18 C1z C 35.4884 -17.1513
19 C1x C 34.6655 -16.0186
20 S2x S 36.3098 -18.2846
21 C1x C 37.6418 -17.8535
22 C1x C 37.6434 -16.4535
23 S2x S 36.3125 -16.0193
24 C6a C 33.3340 -15.0513
25 O6a O 34.5364 -14.3570
26 O6a O 32.1105 -14.3449
27 C8x C 23.6962 -17.8701
28 C8x C 22.4893 -18.5798
29 C8x C 22.5005 -19.9798
30 C8x C 23.6980 -20.6584
31 C8x C 24.9048 -19.9488
32 X Cl 41.7744 -18.1303
BOND 33
1 1 2 1
2 2 3 1
3 2 4 2
4 3 5 1
5 3 6 1 #Up
6 5 7 1
7 7 8 1 #Up
8 7 9 1
9 8 10 1
10 8 11 2
11 9 12 1
12 10 13 1
13 12 14 1
14 13 15 1
15 1 16 1
16 1 17 1
17 17 18 1
18 18 19 1
19 16 19 1
20 18 20 1
21 20 21 1
22 21 22 1
23 22 23 1
24 18 23 1
25 16 24 1 #Down
26 24 25 1
27 24 26 2
28 14 27 2
29 27 28 1
30 28 29 2
31 29 30 1
32 30 31 2
33 14 31 1
|
|---|
