| Entry |
|
|---|
| Name |
Mefloquine hydrochloride (JP18/USP);
Lariam (TN) |
|---|
| Product |
|
|---|
| Generic |
|
|---|
| Formula |
C17H16F6N2O. HCl
|
|---|
| Exact mass |
414.0934
|
|---|
| Mol weight |
414.7731
|
|---|
| Structure |
|
|---|
| Simcomp |
|
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| Class |
Metabolizing enzyme substrate
DG01633 CYP3A substrate
|
|---|
| Remark |
| Therapeutic category: | 6419 |
| Product (DG01020): | D00831<JP/US> |
|
|---|
| Efficacy |
Antimalarial |
|---|
| Disease |
|
|---|
| Comment |
Methanolquinoline
|
|---|
| Metabolism |
|
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| Interaction |
|
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| Structure map |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
P ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
P01 ANTIPROTOZOALS
P01B ANTIMALARIALS
P01BC Methanolquinolines
P01BC02 Mefloquine
D00831 Mefloquine hydrochloride (JP18/USP) <JP/US>
USP drug classification [BR:br08302]
Antiparasitics
Antiprotozoals
Mefloquine
D00831 Mefloquine hydrochloride (JP18/USP)
Therapeutic category of drugs in Japan [BR:br08301]
6 Agents against pathologic organisms and parasites
64 Parasitics (systemic)
641 Antiprotozoans
6419 Others
D00831 Mefloquine hydrochloride (JP18/USP)
Antimicrobials [BR:br08307]
Antiparasitics
Antmalarials
Methanolquinoline
D00831 Mefloquine hydrochloride (JP18/USP) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00831 Mefloquine hydrochloride
New drug approvals in Japan [br08318.html]
Drugs with new active ingredients
D00831
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D00831
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 27
1 C8y C 16.2139 -17.5612
2 C8y C 16.2371 -16.1629
3 C8y C 14.9852 -18.2456
4 N5x N 17.4131 -18.2807
5 C8y C 17.4541 -15.4843
6 C8x C 15.0321 -15.4375
7 C8x C 13.7802 -17.5261
8 C1d C 14.9736 -19.6440
9 C8y C 18.6359 -17.5963
10 C8x C 18.6535 -16.1979
11 C1c C 17.4365 -14.0802
12 C8x C 13.7975 -16.1162
13 X F 13.6395 -19.6381
14 X F 16.4419 -19.6440
15 X F 14.9619 -21.0481
16 C1d C 19.8352 -18.3101
17 C1y C 18.6535 -13.3781
18 O1a O 16.2197 -13.3838
19 X F 21.0405 -19.0121
20 X F 20.5256 -17.0931
21 X F 19.1274 -19.5211
22 C1x C 19.8704 -14.0802
23 N1x N 18.6535 -11.9740
24 C1x C 21.0874 -13.3721
25 C1x C 19.8704 -11.2719
26 C1x C 21.0874 -11.9681
27 X Cl 23.6498 -15.1039
BOND 28
1 1 2 2
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 2
7 3 8 1
8 4 9 2
9 5 10 2
10 5 11 1
11 6 12 2
12 8 13 1
13 8 14 1
14 8 15 1
15 9 16 1
16 11 17 1
17 11 18 1 #Down
18 16 19 1
19 16 20 1
20 16 21 1
21 17 22 1
22 17 23 1
23 22 24 1
24 23 25 1
25 24 26 1
26 7 12 1
27 9 10 1
28 25 26 1
|
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