KEGG   DRUG: Nomifensine maleateHelp
Entry
D05200                      Drug                                   

Name
Nomifensine maleate (USAN);
Merital (TN)
Formula
C16H18N2. C4H4O4
Exact mass
354.158
Mol weight
354.3997
Structure
Mol fileKCF fileDB search
Remark
ATC code: N06AX04
Efficacy
Antidepressant, Selective noradrenaline reuptake inhibitor (NRI)
Target
SLC6A2 (NAT1) [HSA:6530] [KO:K05035]
Interaction
Drug interaction
Structure map
map07234  Neurotransmitter transporter inhibitors
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N06 PSYCHOANALEPTICS
   N06A ANTIDEPRESSANTS
    N06AX Other antidepressants
     N06AX04 Nomifensine
      D05200  Nomifensine maleate (USAN)
Target-based classification of drugs [BR:br08310]
 Transporters
  Solute carrier family
   SLC6
    SLC6A2 (NAT1)
     D05200  Nomifensine maleate (USAN)
BRITE hierarchy
Other DBs
CAS: 32795-47-4
PubChem: 47206919
ChEMBL: CHEMBL1256842
LigandBox: D05200
NIKKAJI: J321.619E
LinkDB All DBs
KCF data Show

ATOM        26
            1   C8x C    18.0630  -17.0885
            2   C8x C    18.0630  -18.4893
            3   C8x C    19.2761  -19.1896
            4   C8y C    20.4893  -18.4893
            5   C8y C    20.4893  -17.0885
            6   C8y C    19.2761  -16.3881
            7   C1y C    21.7024  -19.1896
            8   C1x C    22.9155  -18.4893
            9   N1y N    22.9155  -17.0885
            10  C1x C    21.7024  -16.3881
            11  C8y C    21.7024  -20.5904
            12  C8x C    20.4913  -21.2896
            13  C8x C    20.4913  -22.6904
            14  C8x C    21.7044  -23.3908
            15  C8x C    22.9155  -22.6916
            16  C8x C    22.9155  -21.2908
            17  N1a N    19.2761  -14.9875
            18  C1a C    24.1138  -16.3966
            19  C2b C    29.2600  -18.9700
            20  C2b C    27.4400  -18.9700
            21  C6a C    26.8100  -20.1600
            22  C6a C    29.8900  -20.1600
            23  O6a O    27.4400  -21.3500
            24  O6a O    29.2600  -21.3500
            25  O6a O    31.2900  -20.1600
            26  O6a O    25.4800  -20.1600
BOND        27
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     4   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11    5  10 1
            12    7  11 1
            13   11  12 2
            14   12  13 1
            15   13  14 2
            16   14  15 1
            17   15  16 2
            18   11  16 1
            19    6  17 1
            20    9  18 1
            21   19  20 2
            22   20  21 1
            23   19  22 1
            24   21  23 2
            25   22  24 1
            26   22  25 2
            27   21  26 1

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