| Entry |
|
|---|
| Name |
Prorenoate potassium (USAN/INN) |
|---|
| Formula |
C23H31O4. K
|
|---|
| Exact mass |
410.1859
|
|---|
| Mol weight |
410.59
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG03231 Antihypertensive
DG01676 Aldosterone antagonist
DG01885 Potassium-sparing diuretic
|
|---|
| Efficacy |
Diuretic, Aldosterone antagonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04960 | Aldosterone-regulated sodium reabsorption |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07225 | Glucocorticoid and mineralocorticoid receptor agonists/antagonists |
|
|---|
| Brite |
Drug groups [BR:br08330]
Cardiovascular agent
DG03231 Antihypertensive
DG01676 Aldosterone antagonist
D05640 Prorenoate potassium
DG01885 Potassium-sparing diuretic
D05640 Prorenoate potassium
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Estrogen like receptors
3-Ketosteroid receptor
NR3C2 (MR)
D05640 Prorenoate potassium (USAN/INN)
|
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| Other DBs |
|
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| LinkDB |
|
|---|
| KCF data |
ATOM 28
1 C1y C 26.5300 -19.5300
2 C1y C 25.4800 -18.9000
3 C1y C 27.7200 -18.9000
4 C1y C 26.5300 -20.9300
5 C1z C 24.2200 -19.5300
6 C1x C 25.4800 -17.5700
7 C1z C 27.7200 -17.5700
8 C1x C 30.0300 -18.9000
9 C1y C 25.4100 -21.5600
10 C2y C 24.2200 -20.8600
11 C1x C 23.1000 -18.9000
12 C1a C 24.2200 -18.2700
13 C1x C 26.6000 -16.8700
14 C1z C 28.9100 -16.8700
15 C1x C 30.0300 -17.5700
16 C2x C 23.1000 -21.5600
17 C1x C 21.9100 -19.5300
18 C1b C 30.0300 -16.1700
19 O1a O 28.9100 -15.2600
20 C5x C 21.9100 -20.8600
21 O5x O 20.7200 -21.5600
22 C1a C 27.7200 -16.1700
23 C1b C 31.2662 -16.8271
24 C6a C 32.4828 -16.0671
25 O6a O 33.7302 -16.7301 #-
26 O6a O 32.5050 -14.7007
27 C1x C 26.5300 -22.3300
28 Z K 35.5600 -16.8000 #+
BOND 31
1 1 2 1
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 1
7 3 8 1
8 5 10 1
9 5 11 1
10 5 12 1 #Up
11 6 13 1
12 7 14 1
13 8 15 1
14 10 16 2
15 11 17 1
16 14 18 1 #Down
17 14 19 1 #Up
18 16 20 1
19 20 21 2
20 7 13 1
21 14 15 1
22 17 20 1
23 7 22 1 #Up
24 9 4 1
25 10 9 1
26 18 23 1
27 23 24 1
28 24 25 1
29 24 26 2
30 4 27 1
31 9 27 1
|
|---|
