ORTHOLOGY: K08555
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Entry
K08555 KO
Symbol
NR3C2, MR
Name
mineralocorticoid receptor
Pathway
map04960
Aldosterone-regulated sodium reabsorption
Disease
H00243
Hyperkalemic distal renal tubular acidosis (RTA type 4)
H00603
Hypertension exacerbated in pregnancy
H01633
High blood pressure
H02310
Renal tubular acidosis
Brite
KEGG Orthology (KO) [BR:
ko00001
]
09150 Organismal Systems
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
K08555 NR3C2, MR; mineralocorticoid receptor
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors
K08555 NR3C2, MR; mineralocorticoid receptor
09183 Protein families: signaling and cellular processes
03310 Nuclear receptors
K08555 NR3C2, MR; mineralocorticoid receptor
Transcription factors [BR:
ko03000
]
Eukaryotic type
Zinc finger
Cys4 estrogen receptor-like
K08555 NR3C2, MR; mineralocorticoid receptor
Nuclear receptors [BR:
ko03310
]
3. Estrogen like
3C. 3-Ketosteroid receptor
K08555 NR3C2, MR; mineralocorticoid receptor
BRITE hierarchy
Genes
HSA:
4306
(NR3C2)
PTR:
461533
(NR3C2)
PPS:
100970550
(NR3C2)
GGO:
101137339
(NR3C2)
PON:
100172884
(NR3C2)
PPYG:
129035740
(NR3C2)
NLE:
100584329
(NR3C2)
HMH:
116464826
(NR3C2)
SSYN:
129481112
(NR3C2)
MCC:
704789
(NR3C2)
MCF:
102118229
(NR3C2)
MTHB:
126954881
MNI:
105463453
(NR3C2)
CSAB:
103236358
(NR3C2)
CATY:
105580729
(NR3C2)
PANU:
101025845
(NR3C2)
TGE:
112624577
(NR3C2)
MLEU:
105534518
(NR3C2)
RRO:
104666371
(NR3C2)
RBB:
108514048
(NR3C2)
TFN:
117086001
(NR3C2)
PTEH:
111552910
(NR3C2)
CANG:
105522241
(NR3C2)
CJC:
100405081
(NR3C2)
SBQ:
101031058
(NR3C2)
CIMI:
108307346
(NR3C2)
ANAN:
105729343
(NR3C2)
CSYR:
103267459
(NR3C2)
MMUR:
105881834
(NR3C2)
LCAT:
123638474
(NR3C2)
PCOQ:
105822965
(NR3C2)
OGA:
100956592
(NR3C2)
MMU:
110784
(Nr3c2)
MCAL:
110299932
(Nr3c2)
MPAH:
110337580
(Nr3c2)
RNO:
25672
(Nr3c2)
MCOC:
116069596
(Nr3c2)
ANU:
117723230
(Nr3c2)
MUN:
110560166
(Nr3c2)
CGE:
100750556
(Nr3c2)
MAUA:
101833082
(Nr3c2)
PROB:
127237554
(Nr3c2)
PLEU:
114709925
(Nr3c2)
MORG:
121455666
(Nr3c2)
MFOT:
126489136
AAMP:
119802080
(Nr3c2)
NGI:
103748464
(Nr3c2)
CPOC:
100735309
(Nr3c2)
CCAN:
109697651
(Nr3c2)
DORD:
105995668
(Nr3c2)
DSP:
122127257
(Nr3c2)
PLOP:
125341668
(Nr3c2)
NCAR:
124995063
MMMA:
107141103
(Nr3c2)
OCU:
100358449
103349910
OPI:
101519367
(NR3C2)
TUP:
102497749
(NR3C2)
GVR:
103587359
(NR3C2)
CFA:
475461
(NR3C2)
CLUD:
112654352
(NR3C2)
VVP:
112934698
(NR3C2)
VLG:
121481067
(NR3C2)
NPO:
129516861
(NR3C2)
AML:
100475310
UMR:
103658011
(NR3C2)
UAH:
113255738
(NR3C2)
UAR:
123793227
(NR3C2)
ELK:
111154998
LLV:
125093025
MPUF:
101687999
(NR3C2)
MNP:
132000083
(NR3C2)
MLK:
131832559
(NR3C2)
NVS:
122889597
(NR3C2)
ORO:
101386208
(NR3C2)
EJU:
114225556
(NR3C2)
ZCA:
113925303
(NR3C2)
MLX:
118022257
(NR3C2)
NSU:
110588473
(NR3C2)
LWW:
102745228
FCA:
101081977
(NR3C2)
PYU:
121028744
(NR3C2)
PCOO:
112858014
(NR3C2)
PBG:
122475715
(NR3C2)
PVIV:
125164354
(NR3C2)
LRUF:
124520702
PTG:
102951221
(NR3C2)
PPAD:
109262546
(NR3C2)
PUC:
125923141
AJU:
106983308
HHV:
120246309
(NR3C2)
BTA:
537614
(NR3C2)
BOM:
102269594
BIU:
109571245
(NR3C2)
BBUB:
102395884
(NR3C2)
BBIS:
104989175
(NR3C2)
CHX:
102172834
(NR3C2)
OAS:
101107046
(NR3C2)
BTAX:
128062237
(NR3C2)
ODA:
120871451
(NR3C2)
CCAD:
122451839
(NR3C2)
MBEZ:
129542840
(NR3C2)
SSC:
100620970
(NR3C2)
CFR:
102520495
(NR3C2)
CBAI:
105071334
CDK:
105091218
(NR3C2)
VPC:
102533849
(NR3C2)
BACU:
103008784
(NR3C2)
BMUS:
118895961
(NR3C2)
LVE:
103088347
OOR:
101271468
(NR3C2)
DLE:
111187724
(NR3C2)
PCAD:
102988649
(NR3C2)
PSIU:
116754584
(NR3C2)
NASI:
112393788
(NR3C2)
ECB:
100062570
(NR3C2)
EPZ:
103546877
(NR3C2)
EAI:
106829181
(NR3C2)
MYB:
102248146
(NR3C2)
MYD:
102768764
(NR3C2)
MMYO:
118657639
(NR3C2)
MLF:
102439464
(NR3C2)
MDT:
132235474
(NR3C2)
PKL:
118711689
(NR3C2)
EFUS:
103288266
(NR3C2)
MNA:
107532505
(NR3C2)
DRO:
112312235
(NR3C2)
SHON:
118995411
(NR3C2)
AJM:
119061719
(NR3C2)
PDIC:
114502878
(NR3C2)
PHAS:
123813735
(NR3C2)
MMF:
118615756
(NR3C2)
PPAM:
129061883
(NR3C2)
HAI:
109392734
(NR3C2)
RFQ:
117037965
(NR3C2)
PALE:
102897003
(NR3C2)
PGIG:
120613307
(NR3C2)
PVP:
105291547
(NR3C2)
RAY:
107517767
(NR3C2)
MJV:
108398605
(NR3C2)
TOD:
119234904
(NR3C2)
SARA:
101545737
(NR3C2)
SETR:
126003687
(NR3C2)
LAV:
100661181
(NR3C2)
TMU:
101349203
ETF:
101640378
(NR3C2)
DNM:
101411727
(NR3C2)
MDO:
100018377
(NR3C2)
GAS:
123252957
(NR3C2)
SHR:
100917276
(NR3C2)
AFZ:
127540726
PCW:
110213647
(NR3C2)
TVP:
118853375
(NR3C2)
OAA:
100080085
(NR3C2)
GGA:
374131
(NR3C2)
PCOC:
116226132
(NR3C2)
MGP:
100546597
(NR3C2)
CJO:
107313140
(NR3C2)
TPAI:
128084306
(NR3C2)
LMUT:
125692302
(NR3C2)
NMEL:
110398595
(NR3C2)
APLA:
101798001
(NR3C2)
ACYG:
106032234
(NR3C2)
CATA:
118248720
(NR3C2)
AFUL:
116488466
(NR3C2)
TGU:
751776
(NR3C2)
LSR:
110473779
(NR3C2)
SCAN:
103826080
(NR3C2)
PMOA:
120497221
(NR3C2)
OTC:
121339854
(NR3C2)
PRUF:
121365221
(NR3C2)
GFR:
102038615
(NR3C2)
FAB:
101819228
(NR3C2)
OMA:
130252823
(NR3C2)
PHI:
102111766
(NR3C2)
PMAJ:
107202999
(NR3C2)
CCAE:
111928848
(NR3C2)
CCW:
104697243
(NR3C2)
CBRC:
103622347
(NR3C2)
ETL:
114062336
(NR3C2)
ZAB:
102067653
(NR3C2)
ZLE:
135446834
(NR3C2)
ACHL:
103800797
SVG:
106855683
(NR3C2)
MMEA:
130575347
(NR3C2)
HRT:
120752653
(NR3C2)
SATI:
136360646
(NR3C2)
FPG:
101917775
(NR3C2)
FCH:
102057989
(NR3C2)
CCRI:
104163360
(NR3C2)
NNT:
104401677
SHAB:
115610274
(NR3C2)
ACUN:
113479743
(NR3C2)
TALA:
104367599
(NR3C2)
ACHC:
115336110
(NR3C2)
HALD:
104314298
(NR3C2)
HLE:
104837178
(NR3C2)
AGEN:
126044820
GCL:
127015417
CSTI:
104551575
(NR3C2)
LDI:
104341550
(NR3C2)
MNB:
103771833
(NR3C2)
DPUB:
104297115
(NR3C2)
AVIT:
104272353
BRHI:
104497768
EGZ:
104130587
(NR3C2)
NNI:
104015967
(NR3C2)
PCRI:
104038068
(NR3C2)
PCAO:
104040493
PADL:
103919904
(NR3C2)
AFOR:
103899757
(NR3C2)
FGA:
104069508
(NR3C2)
GSTE:
104250265
CLV:
102095900
(NR3C2)
MUI:
104544651
(NR3C2)
PGUU:
104464622
PLET:
104615555
EHS:
104504792
(NR3C2)
CMAC:
104484996
(NR3C2)
CUCA:
104066080
(NR3C2)
TEO:
104383508
(NR3C2)
BREG:
104632498
(NR3C2)
OHA:
104337010
(NR3C2)
ACAR:
104519519
CPEA:
104398791
(NR3C2)
CVF:
104291498
(NR3C2)
RTD:
128909842
(NR3C2)
AAM:
106492011
(NR3C2)
AROW:
112976368
(NR3C2)
NPD:
112950124
(NR3C2)
TGT:
104578584
(NR3C2)
DNE:
112986851
(NR3C2)
SCAM:
104153363
(NR3C2)
ASN:
102368785
(NR3C2)
AMJ:
102567668
(NR3C2)
CPOO:
109309657
(NR3C2)
GGN:
109301206
(NR3C2)
PSS:
102456908
(NR3C2)
CMY:
102932569
(NR3C2)
CCAY:
125635337
(NR3C2)
DCC:
119854303
(NR3C2)
CPIC:
101937034
(NR3C2)
TST:
117878325
(NR3C2)
CABI:
116832480
(NR3C2)
MRV:
120406716
(NR3C2)
ACS:
100566367
(nr3c2)
ASAO:
132776810
(NR3C2)
PVT:
110073618
(NR3C2)
SUND:
121930435
(NR3C2)
PBI:
103066436
(NR3C2)
PMUR:
114922595
CTIG:
120313591
(NR3C2)
TSR:
106548648
(NR3C2)
PGUT:
117680248
(NR3C2)
APRI:
131202999
(NR3C2)
PTEX:
113434754
(NR3C2)
NSS:
113412869
(NR3C2)
VKO:
123023768
(NR3C2)
PMUA:
114604751
(NR3C2)
PRAF:
128421004
(NR3C2)
ZVI:
118084503
(NR3C2)
HCG:
128326930
(NR3C2)
GJA:
107116535
(NR3C2)
STOW:
125439842
(NR3C2)
EMC:
129336548
(NR3C2)
XLA:
108706664
(nr3c2.S)
399290
(nr3c2.L)
XTR:
100487449
(nr3c2)
NPR:
108785218
(NR3C2)
RTEM:
120919630
(NR3C2)
BBUF:
120990029
(NR3C2)
BGAR:
122942989
(NR3C2)
MUO:
115461665
(NR3C2)
GSH:
117358792
(NR3C2)
DRE:
562171
(nr3c2)
SRX:
107734552
(nr3c2)
107742541
SANH:
107654985
107670737
SGH:
107550687
CCAR:
109091306
109105895
CAUA:
113095014
113111650
CGIB:
127949161
128016377
PTET:
122346212
(nr3c2)
LROH:
127169689
(nr3c2)
OMC:
131535913
(nr3c2)
PPRM:
120492754
120492781
(nr3c2)
RKG:
130105633
(nr3c2)
MAMB:
125272092
(nr3c2)
CIDE:
127514765
CERY:
137033181
(nr3c2)
MASI:
127443881
127445462
TROS:
130552352
(nr3c2)
TDW:
130435431
(nr3c2)
MANU:
129444431
(nr3c2)
IPU:
108263320
IFU:
128606084
(nr3c2)
PHYP:
113538995
(nr3c2)
SMEO:
124375282
(nr3c2)
TFD:
113662681
(nr3c2)
TVC:
132847651
(nr3c2)
TRN:
134315186
AMEX:
103045817
(nr3c2)
CMAO:
118810832
(nr3c2)
EEE:
113589544
(nr3c2)
CHAR:
105903549
(nr3c2)
TRU:
101068934
(nr3c2)
TFS:
130527780
(nr3c2)
TNG:
GSTEN00032894G001
LCO:
104917971
(nr3c2)
NCC:
104949230
(nr3c2)
TBEN:
117482136
(nr3c2)
CGOB:
115011464
(nr3c2)
PGEO:
117448756
(nr3c2)
GACU:
117556179
(nr3c2)
EMAC:
134864550
(nr3c2)
ELY:
117255415
(nr3c2)
EFO:
125886272
(nr3c2)
PLEP:
121941668
(nr3c2)
SLUC:
116034403
(nr3c2)
ECRA:
117935437
(nr3c2)
ESP:
116705683
(nr3c2)
PFLV:
114546234
(nr3c2)
GAT:
120825252
(nr3c2)
PPUG:
119217472
(nr3c2)
AFB:
129096150
(nr3c2)
CLUM:
117735531
(nr3c2)
PSWI:
130189714
(nr3c2)
MSAM:
119898848
(nr3c2)
SCHU:
122873414
(nr3c2)
CUD:
121508093
(nr3c2)
ALAT:
119025284
(nr3c2)
MZE:
101466971
(nr3c2)
ONL:
100712208
(nr3c2)
OAU:
116330132
(nr3c2)
OLA:
100302443
(nr3c2)
OML:
112137377
(nr3c2)
CSAI:
133441037
(nr3c2)
XMA:
102235678
(nr3c2)
XCO:
114144705
(nr3c2)
XHE:
116719827
(nr3c2)
PRET:
103471378
(nr3c2)
PFOR:
103144846
(nr3c2)
PLAI:
106962265
PMEI:
106905099
GAF:
122829821
(nr3c2)
CVG:
107094929
(nr3c2)
CTUL:
119773889
GMU:
124867854
(nr3c2)
NFU:
107389617
(nr3c2)
KMR:
108230667
(nr3c2)
ALIM:
106527549
(nr3c2)
NWH:
119422579
(nr3c2)
AOCE:
111563254
(nr3c2)
MCEP:
125004115
(nr3c2)
CSEM:
103383356
(nr3c2)
POV:
109638349
(nr3c2)
SSEN:
122770676
(nr3c2)
HHIP:
117771457
(nr3c2)
HSP:
118116318
(nr3c2)
PPLT:
128437553
(nr3c2)
SMAU:
118312493
(nr3c2)
LCF:
108893065
SDU:
111216652
(nr3c2)
SLAL:
111652930
(nr3c2)
XGL:
120799649
(nr3c2)
HCQ:
109511363
(nr3c2)
SSCV:
125968801
SBIA:
133505593
(nr3c2)
PEE:
133403950
(nr3c2)
PTAO:
133476918
(nr3c2)
BPEC:
110168794
MALB:
109955522
(nr3c2)
BSPL:
114855067
(nr3c2)
SJO:
128371077
(nr3c2)
SASA:
106602364
106610192
STRU:
115191799
115202228
OTW:
112261287
112261291
OMY:
100136210
(mra)
100136953
(mrb)
OGO:
124001783
124012602
ONE:
115137495
115145597
OKI:
109881008
109901290
OKE:
118361871
118375786
SALP:
111958481
SNH:
120034956
120053049
CCLU:
121536016
123482121
ELS:
105020929
(nr3c2)
SFM:
108924478
108936702
PKI:
111833165
111837269
(nr3c2)
AANG:
118226724
118231565
(nr3c2)
LOC:
102691674
(nr3c2)
PSPA:
121296858
121321317
(nr3c2)
ARUT:
117409242
(nr3c2)
117421141
PSEX:
120527132
(nr3c2)
LCM:
102358348
(NR3C2)
CMK:
103185495
(nr3c2)
RTP:
109934659
CPLA:
122554435
(nr3c2)
HOC:
132817106
(nr3c2)
LERI:
129703866
(nr3c2)
PMRN:
103091764
(NR3C2)
LRJ:
133342989
(NR3C2)
DFR:
124490239
» show all
Taxonomy
UniProt
Reference
PMID:
3037703
Authors
Arriza JL, Weinberger C, Cerelli G, Glaser TM, Handelin BL, Housman DE, Evans RM
Title
Cloning of human mineralocorticoid receptor complementary DNA: structural and functional kinship with the glucocorticoid receptor.
Journal
Science 237:268-75 (1987)
DOI:
10.1126/science.3037703
Sequence
[hsa:
4306
]
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