KEGG   DRUG: Sodium oxybate
Entry
D05866                      Drug                                   
Name
Sodium oxybate (USAN);
Sodium gammahydroxybutyrate;
Xyrem (TN)
Product
LUMRYZ (Avadel CNS Pharmaceuticals), XYREM (Jazz Pharmaceuticals)
  Generic
SODIUM OXYBATE (Amneal Pharmaceuticals NY LLC), SODIUM OXYBATE (Hikma Pharmaceuticals USA)
Formula
C4H7O3. Na
Exact mass
126.0293
Mol weight
126.0863
Structure
Simcomp
Class
Neuropsychiatric agent
 DG02030  Anesthetics
  DG02027  General anesthetics
Remark
ATC code: N01AX11 N07XX04
Chemical structure group: DG00798
Product (DG00798): D05866<US>
Product (mixture): D12131<US>
Efficacy
Anesthetic (adjunct)
  Disease
Narcolepsy [DS:H01293]
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N01 ANESTHETICS
   N01A ANESTHETICS, GENERAL
    N01AX Other general anesthetics
     N01AX11 Sodium oxybate
      D05866  Sodium oxybate (USAN) <US>
  N07 OTHER NERVOUS SYSTEM DRUGS
   N07X OTHER NERVOUS SYSTEM DRUGS
    N07XX Other nervous system drugs
     N07XX04 Sodium oxybate
      D05866  Sodium oxybate (USAN) <US>
USP drug classification [BR:br08302]
 Sleep Disorder Agents
  Wakefulness Promoting Agents
   Sodium Oxybate
    D05866  Sodium oxybate (USAN)
Drug groups [BR:br08330]
 Neuropsychiatric agent
  DG02030  Anesthetics
   DG02027  General anesthetics
    DG00798  Hydroxybutyric acid
     D05866  Sodium oxybate
New drug approvals in the USA [br08319.html]
 New molecular entities and new therapeutic biological products
  D05866
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D05866
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D05866
Pharmacogenomic biomarkers [br08341.html]
 Polymorphisms and mutations affecting drug response
  D05866
Drug groups [BR:br08330]
 Neuropsychiatric agent
  DG02030  Anesthetics
   DG02027  General anesthetics
    DG00798  Hydroxybutyric acid
Other DBs
CAS: 502-85-2
PubChem: 47207527
LigandBox: D05866
NIKKAJI: J6.207C
LinkDB
KCF data

ATOM        8
            1   O1a O    14.4900  -16.5200
            2   C1b C    15.6800  -17.2200
            3   C1b C    16.9400  -16.5200
            4   C1b C    18.1300  -17.2200
            5   C6a C    19.3200  -16.5200
            6   O6a O    20.5800  -17.2200 #-
            7   O6a O    19.3200  -15.1200
            8   Z   Na   22.5400  -17.2200 #+
BOND        6
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     5   7 2

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