KEGG   DRUG: SomatremHelp
Entry
D05884                      Drug                                   

Name
Somatrem (USAN);
Somatrem (genetical recombination) (JAN);
Protropin (TN)
Formula
C995H1537N263O301S8
Exact mass
22242.0814
Mol weight
22255.9518
Sequence
Met Phe Pro Thr Ile Pro Leu Ser Arg Leu Phe Asp Asn Ala Met Leu
Arg Ala His Arg Leu His Gln Leu Ala Phe Asp Thr Tyr Gln Glu Phe
Glu Glu Ala Tyr Ile Pro Lys Glu Gln Lys Tyr Ser Phe Leu Gln Asn
Pro Gln Thr Ser Leu Cys Phe Ser Glu Ser Ile Pro Thr Pro Ser Asn
Arg Glu Glu Thr Gln Gln Lys Ser Asn Leu Glu Leu Leu Arg Ile Ser
Leu Leu Leu Ile Gln Ser Trp Leu Glu Pro Val Gln Phe Leu Arg Ser
Val Phe Ala Asn Ser Ser Val Tyr Gly Ala Ser Asp Ser Asn Val Tyr
Asp Leu Leu Lys Asp Leu Glu Glu Gly Ile Gln Thr Leu Met Gly Arg
Leu Glu Asp Gly Ser Pro Arg Thr Gly Gly Ile Phe Lys Gln Thr Tyr
Ser Lys Phe Asp Thr Asn Ser His Asn Asp Asp Ala Leu Leu Lys Asn
Tyr Gly Leu Leu Tyr Cys Phe Arg Lys Asp Met Asp Lys Val Glu Thr
Phe Leu Arg Ile Val Gln Cys Arg Ser Val Glu Gly Ser Cys Gly Phe
  Type
Peptide
Remark
ATC code: H01AC02
Efficacy
Growth hormone (GH) receptor agonist
Comment
human growth hormone derivative
Target
GHR [HSA:2690] [KO:K05080]
  Pathway
hsa04060  Cytokine-cytokine receptor interaction
hsa04080  Neuroactive ligand-receptor interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
  H01 PITUITARY AND HYPOTHALAMIC HORMONES AND ANALOGUES
   H01A ANTERIOR PITUITARY LOBE HORMONES AND ANALOGUES
    H01AC Somatropin and somatropin agonists
     H01AC02 Somatrem
      D05884  Somatrem (USAN)
Target-based classification of drugs [BR:br08310]
 Cytokines and receptors
  Cytokine receptors
   CSF and other factor receptors
    GHR
     D05884  Somatrem (USAN)
BRITE hierarchy
Other DBs
CAS: 82030-87-3
PubChem: 47207545
LinkDB All DBs

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