KEGG ORTHOLOGY: K05080

ORTHOLOGY: K05080

Entry

K05080                      KO

Symbol

GHR

Name

growth hormone receptor

Pathway

map04060

Cytokine-cytokine receptor interaction

map04080

Neuroactive ligand-receptor interaction

map04151

PI3K-Akt signaling pathway

map04630

JAK-STAT signaling pathway

map04935

Growth hormone synthesis, secretion and action

Disease

H00155

Familial hypercholesterolemia

H00254

Growth hormone deficiency

H02037

Laron syndrome

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05080  GHR; growth hormone receptor
   04151 PI3K-Akt signaling pathway
    K05080  GHR; growth hormone receptor
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K05080  GHR; growth hormone receptor
   04060 Cytokine-cytokine receptor interaction
    K05080  GHR; growth hormone receptor
09150 Organismal Systems
  09152 Endocrine system
   04935 Growth hormone synthesis, secretion and action
    K05080  GHR; growth hormone receptor
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05080  GHR; growth hormone receptor
Cytokine receptors [BR:ko04050]
Interleukin receptor families
  Prolactin receptor family
   K05080  GHR; growth hormone receptor

Other DBs

GO:

0004903

Genes

HSA:

2690(GHR)

PTR:	471560(GHR)

PPS:	100980367(GHR)

GGO:	101147704(GHR)

PON:	100451189(GHR)

PPYG:

129036932(GHR)

NLE:	100600868(GHR)

HMH:	116456888(GHR)

SSYN:

129464514(GHR)

MCC:	697986(GHR)

MCF:	102121279(GHR)

MTHB:

126956470

MNI:	105487459(GHR)

CSAB:

103215199(GHR)

CATY:

105583480(GHR)

PANU:

100126695(GHR)

TGE:	112626058(GHR)

MLEU:

105529330(GHR)

RRO:	104667785(GHR)

RBB:	108526376(GHR)

TFN:	117065066(GHR)

PTEH:

111545572(GHR)

CANG:

105520629(GHR)

CJC:	100399027(GHR)

SBQ:	101042350(GHR)

CIMI:

108307700(GHR)

ANAN:

105704541(GHR)

CSYR:

103254706(GHR)

MMUR:

105878381(GHR)

LCAT:

123648039(GHR)

PCOQ:

105826710(GHR)

OGA:	100966148(GHR)

MMU:	14600(Ghr)

MPAH:

110328813(Ghr)

RNO:	25235(Ghr)

MCOC:

116083333(Ghr)

ANU:	117723781(Ghr)

MUN:	110563813(Ghr)

CGE:	100763540(Ghr)

MAUA:

101829135(Ghr)

PROB:

127220594(Ghr)

PLEU:

114697329(Ghr)

MORG:

121432909 121444546

MFOT:

126499710

AAMP:

119808721(Ghr)

NGI:	103741346(Ghr)

HGL:	101716037(Ghr)

CPOC:

100135527(Ghr)

CCAN:

109697601(Ghr)

DORD:

105987389(Ghr)

DSP:	122116965(Ghr)

PLOP:

125367503(Ghr)

NCAR:

124987665

MMMA:

107146390(Ghr)

OCU:	100009325(GHR)

OPI:	101516827(GHR)

TUP:	102475227(GHR)

GVR:	103585669(GHR)

CFA:	403721(GHR)

CLUD:

112652645(GHR)

VVP:	112933508(GHR)

VLG:	121486739(GHR)

NPO:	129509486(GHR)

AML:	100422780(GHR)

UMR:	103664663(GHR)

UAH:	113260944(GHR)

UAR:	123785520(GHR)

ELK:

111140951

LLV:

125100950

MPUF:

101689245(GHR)

MNP:	132028281(GHR)

MLK:	131831705(GHR)

NVS:	122894598(GHR)

ORO:	101370443(GHR)

EJU:	114204796(GHR)

ZCA:	113928812(GHR)

MLX:	118006412 118006541

NSU:	110589921(GHR)

LWW:

102740053

FCA:	101093244(GHR)

PYU:	121044224(GHR)

PCOO:

112860917(GHR)

PBG:	122494164(GHR)

PVIV:

125170240(GHR)

LRUF:

124507433

PTG:	102952019(GHR)

PPAD:

109275863(GHR)

PUC:

125935006

AJU:

106970898

HHV:	120233060(GHR)

BTA:	280805(GHR)

BOM:	102268311(GHR)

BIU:	109574810(GHR)

BBUB:

102410211(GHR)

BBIS:

104983362(GHR)

CHX:	100860790(GHR)

OAS:	443333(GHR)

BTAX:

128065987(GHR)

ODA:	120879428(GHR)

CCAD:

122454465(GHR)

MBEZ:

129553292(GHR)

SSC:	397488(GHR)

CFR:	102511929(GHR)

CBAI:

105070877(GHR)

CDK:	105106998(GHR)

VPC:	102537399(GHR)

BACU:

103002001(GHR)

BMUS:

118893549(GHR)

LVE:	103069416(GHR)

OOR:	101284890(GHR)

DLE:	111187036(GHR)

PCAD:

102996314(GHR)

PSIU:

116751870(GHR)

NASI:

112396558(GHR)

ECB:	100053020(GHR)

EPZ:	103553842(GHR)

EAI:	106840032(GHR)

MYB:	102252226(GHR)

MYD:	102761733(GHR)

MMYO:

118656324(GHR)

MLF:

102429474

MDT:	132233722(GHR)

PKL:	118702907(GHR)

EFUS:

103298830(GHR)

MNA:	107545625(GHR)

DRO:	112321076(GHR)

SHON:

118998815(GHR)

AJM:	119044242(GHR)

PDIC:

114510955(GHR)

PHAS:

123824618(GHR)

MMF:	118642611(GHR)

PPAM:

129079016(GHR)

HAI:	109375245(GHR)

RFQ:	117024708(GHR)

PALE:

102891638(GHR)

PGIG:

120586151(GHR)

PVP:	105299105(GHR)

RAY:	107504486(GHR)

MJV:	108400493(GHR)

TOD:	119261160(GHR)

SARA:

101540370(GHR)

SETR:

126001066(GHR)

LAV:	100660760(GHR)

TMU:

101353524

ETF:	101657488(GHR)

DNM:	101416890(GHR)

MDO:	554180(GHR)

GAS:	123251948(GHR)

SHR:	100927655(GHR)

AFZ:

127556894

PCW:	110216101(GHR)

TVP:	118850255(GHR)

OAA:	100085538(GHR)

GGA:	408184(GHR)

PCOC:

116239493(GHR)

MGP:

100546929

CJO:	107305958(GHR)

TPAI:

128074474(GHR)

LMUT:

125686659(GHR)

NMEL:

110389657(GHR)

APLA:

101800483(GHR)

ACYG:

106036341(GHR)

CATA:

118257779(GHR)

AFUL:

116500482(GHR)

TGU:	100222341(GHR)

LSR:	110483764(GHR)

SCAN:

103821021(GHR)

PMOA:

120502465(GHR)

OTC:	121346608(GHR)

PRUF:

121365260(GHR)

GFR:	102034223(GHR)

FAB:	101813131(GHR)

OMA:	130264705(GHR)

PHI:	102101864(GHR)

PMAJ:

107216278(GHR)

CCAE:

111941452(GHR)

CCW:	104686635(GHR)

CBRC:

103612904(GHR)

ETL:	114056056(GHR)

ZAB:	102073902(GHR)

ZLE:	135459755(GHR)

ACHL:

103811827(GHR)

SVG:	106857899(GHR)

MMEA:

130572796(GHR)

HRT:	120765197(GHR)

SATI:

136374429(GHR)

FPG:	101923548(GHR)

FCH:	102049860(GHR)

CCRI:

104155097(GHR)

NNT:	104407771(GHR)

SHAB:

115600787(GHR)

ACUN:

113489859(GHR)

TALA:

104357366(GHR)

ACHC:

115337474(GHR) 121232759

HALD:

104325022(GHR)

HLE:	104843071(GHR)

AGEN:

126035273 126035639

GCL:	127027516 127027958

CSTI:

104560079(GHR)

LDI:	104354126(GHR)

MNB:	103775988(GHR)

DPUB:

104307546(GHR)

AVIT:

104274023(GHR)

BRHI:

104492818(GHR)

EGZ:	104121811(GHR)

NNI:	104009742 104020641(GHR)

PCRI:

104027374(GHR)

PCAO:

104042390(GHR)

PADL:

103917288(GHR)

AFOR:

103895037(GHR)

FGA:	104075482(GHR)

GSTE:

104265036(GHR)

CLV:	102085422(GHR)

MUI:	104534543(GHR)

PGUU:

104462200(GHR)

PLET:

104621670(GHR)

EHS:	104503816(GHR)

CMAC:

104487203(GHR)

CUCA:

104062812(GHR)

TEO:

104370932

BREG:

104638524(GHR)

OHA:	104337690(GHR)

ACAR:

104525278(GHR)

CPEA:

104392224(GHR)

CVF:	104294967(GHR)

RTD:	128902177(GHR)

AAM:	106499487(GHR)

AROW:

112964619(GHR)

NPD:	112945961(GHR)

TGT:	104580863(GHR)

DNE:	112992471(GHR)

SCAM:

104140574(GHR)

ASN:	102383050(GHR)

AMJ:	102559799(GHR)

CPOO:

109307870(GHR)

GGN:	109297857(GHR)

PSS:	102446030(GHR)

CMY:	102936927(GHR)

CCAY:

125636971(GHR)

DCC:	119856134(GHR)

CPIC:

101933105(GHR)

TST:	117878663(GHR)

CABI:

116825106(GHR)

MRV:	120408290(GHR)

ACS:	100565883(ghr)

ASAO:

132766957(GHR)

PVT:	110073909(GHR)

SUND:

121920271(GHR)

PBI:	103052977(GHR)

PMUR:

107288499(GHR)

CTIG:

120318581(GHR)

TSR:

106549548

PGUT:

117679154(GHR)

APRI:

131191589(GHR)

PTEX:

113446465(GHR)

VKO:	123031460(GHR)

PMUA:

114606139(GHR)

PRAF:

128423100(GHR)

ZVI:	118077233(GHR)

HCG:	128343357(GHR)

GJA:	107121556(GHR)

STOW:

125436879(GHR)

EMC:	129334385(GHR)

XLA:	108707301(ghr.S) 398153(ghr.L)

XTR:	100493377(ghr)

NPR:	108791746(GHR)

RTEM:

120931814(GHR)

BBUF:

120992365(GHR)

BGAR:

122924768(GHR)

MUO:	115462965(GHR)

GSH:	117354453(GHR)

DRE:	100001424(ghra)

SRX:	107706504 107711892 107724907

SANH:

107681155 107683153 107686406 107703572

SGH:	107589253(ghr) 107591690 107599995 107602865

CCAR:

109046061 109083469 109094852 109095237

CAUA:

113038907 113064226 113096320 113107685

CGIB:

127949614 127952716 127963820 127980869 128015007 128018508

PTET:

122344871 122350638(ghra) 122353060

LROH:

127166237 127169649(ghra) 127171041

OMC:	131541836 131545277(ghra)

PPRM:

120485039(ghra) 120490713(ghrb)

RKG:	130072434(ghra) 130082200

MAMB:

125253098(ghrb) 125279662(ghra)

CIDE:

127516116 127517861

CERY:

137027063(ghra) 137032192

MASI:

127414990 127424373 127443443

TROS:

130553472 130568119 130568324

TDW:	130433355 130439919(ghra)

MANU:

129413576(ghra) 129445176

IPU:	100304685(ghrb) 108264905(ghra)

IFU:

128602394

PHYP:

113543166(ghr) 113546097

SMEO:

124397807(ghrb) 124399975(ghra)

TFD:	113638618(ghrb) 113658550(ghra)

TVC:	132839369 132853311(ghra)

TRN:	134318515(ghra) 134329543

AMEX:

103029077(ghra) 103038295(ghrb)

CMAO:

118798297 118813023(ghra)

EEE:	113578887 113588452(ghr)

CHAR:

105896518 105904309(ghra)

TRU:	101070051(ghr2) 101072280(ghr1) 101079667

TFS:	130517121(ghrb) 130523004 130525924(ghra)

TNG:	GSTEN00019428G001 GSTEN00030887G001

LCO:	104920655(ghr) 104928485

NCC:	104943312(ghr) 104947419

TBEN:

117472922(ghra) 117478902(ghrb) 117486801

CGOB:

115005116 115013290(ghr) 115017159

PGEO:

117441504 117452199(ghra) 117455888

GACU:

117542923 117546085 117558626(ghra)

EMAC:

134860880 134868306 134873671(ghra)

ELY:	117250236 117252454(ghra) 117269557(ghrb)

EFO:	125884828 125889985(ghra) 125905780(ghrb)

PLEP:

121944574(ghra) 121959708(ghrb) 121962928 121963062

SLUC:

116034736(ghrb) 116044846 116054378(ghra)

ECRA:

117939679 117945114(ghra) 117959287(ghrb)

ESP:	116673730 116689547 116704142

PFLV:

114550998 114555274 114571503

GAT:	120819666 120830942(ghra) 120832027(ghrb)

PPUG:

119220346 119225017(ghra) 119226678(ghrb)

AFB:	129100730(ghra) 129102061(ghrb) 129112001

CLUM:

117736215(ghra) 117740885(ghrb) 117741105

PSWI:

130196253(ghra) 130204602 130205120(ghrb)

MSAM:

119892481(ghra) 119915103

SCHU:

122865544(ghrb) 122871817 122876140(ghra)

CUD:	121506054 121509320(ghra) 121525004(ghrb)

ALAT:

119015237 119020111(ghra) 119029932(ghrb)

ASTR:

137591276 137592468(ghra) 137608054

MZE:	101464862 101464917 101481295

ONL:	100534400(ghra) 100534534(ghr) 100690327

OAU:	116310536(ghra) 116324925(ghrb) 116325326

OLA:	100125809(ghr) 100144349(ghr) 101164128

OML:	112148157(ghra) 112152490 112156776

CSAI:

133424938 133450609(ghra) 133455455

XMA:	102218071(ghr) 102233795 102235854

XCO:	114140572 114149781 114154037

XHE:	116716066 116724538 116729265(ghr)

PRET:

103457105 103470141 103474042

PFOR:

103130710(ghr) 103141809 103154115

PLAI:

106939812 106941166 106949508

PMEI:

106915271 106919581 106926766(ghr)

GAF:	122826949 122827695(ghra)

PPRL:

129353039 129358063 129365789(ghra)

CVG:	107093843(ghr) 107094674 107096826

CTUL:

119791465 119794644 119798564(ghra)

GMU:	124861931 124873136(ghrb) 124877201(ghra)

NFU:	107375065 107384629 107394104(ghr)

KMR:	108233781(ghra) 108250916(ghrb) 108251543

ALIM:

106527018 106528313 106530359(ghr)

NWH:	119424456(ghrb) 119429056

AOCE:

111572695 111573340 111575664

MCEP:

124996920(ghrB) 125000657 125012913(ghrA)

CSEM:

103389092 103397680(ghr)

POV:	109639332(ghr) 109644124

SSEN:

122758188 122761290 122765194 122769769(ghra)

HHIP:

117768215(ghra) 117772266(ghrb) 117776679

HSP:	118103157 118114545(ghra) 118125487(ghrb)

PPLT:

128425170(ghrb) 128431317 128437799(ghra)

SMAU:

118285436(ghrb) 118307627 118314184(ghra)

LCF:	108873050 108882565 108901115(ghrb)

SDU:	111221123 111230808

SLAL:

111645138 111669335

XGL:	120798363 120805117(ghra) 120806158

HCQ:	109517519 109524008(ghr)

SSCV:

125965799 125979621 125988474

SBIA:

133490984(ghrb) 133499532(ghra) 133507260

PEE:	133399914(ghra) 133405911 133413658(ghrb)

PTAO:

133475232(ghra) 133480867 133490049(ghrb)

BPEC:

110156618 110167872 110172135(ghr)

MALB:

109956524(ghr) 109973650

BSPL:

114851147 114862264(ghra) 114866558(ghrb)

SJO:	128364640(ghra) 128380022(ghrb)

SASA:

100136442(ghr1) 100136463 100196588(slr) 106585200

STRU:

115159608 115164182 115179197 115196374 115200461 115204032

OTW:	112220395 112230954(ghrb) 112248823(ghra) 112262593

OMY:	100135988 100136277(ghr1) 100136789(ghr) 110525975(ghra)

OGO:	124006843 124021050 124034081(ghra) 124036563 124049000(ghrb)

ONE:	115101134 115111872 115122219 115140321

OKI:	109868115 109873840 109873964 109875971 109896160

OKE:	118358550 118383227 118385342(ghrb) 118387496 118393491(ghra)

SALP:

111958193 111961654 111963987 111974078

SNH:	120021228 120025806 120033459 120043322 120063271

CCLU:

121541637 121547809 121581895 121582555 121585131

ELS:	105015061 105023337

SFM:	108932026 108938566

PKI:	111839225(ghr) 111851429

AANG:

118207057(ghra) 118212918 118213928 118224855

LOC:	102692870(ghr)

PSPA:

121300445 121301616 121317121

ARUT:

117401398 117403905 117406215 117962288 117962629

PSEX:

120532542(ghra)

LCM:	102353866(GHR)

CMK:

RTP:

CPLA:

HOC:

LERI:

LRJ:

Reference

PMID:12421667

Authors

Grotzinger J

Title

Molecular mechanisms of cytokine receptor activation.

Journal

Biochim Biophys Acta 1592:215-23 (2002)
DOI:10.1016/S0167-4889(02)00316-6

Reference

PMID:2825030

Authors

Leung DW, Spencer SA, Cachianes G, Hammonds RG, Collins C, Henzel WJ, Barnard R, Waters MJ, Wood WI

Title

Growth hormone receptor and serum binding protein: purification, cloning and expression.

Journal

Nature 330:537-43 (1987)
DOI:10.1038/330537a0

Sequence

[hsa:2690]

LinkDB

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