| Entry |
|
|---|
| Name |
Spiroxasone (USAN/INN) |
|---|
| Formula |
C24H34O3S
|
|---|
| Exact mass |
402.2229
|
|---|
| Mol weight |
402.59
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG03231 Antihypertensive
DG01676 Aldosterone antagonist
DG01885 Potassium-sparing diuretic
|
|---|
| Efficacy |
Diuretic, Aldosterone antagonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04960 | Aldosterone-regulated sodium reabsorption |
|
|---|
| Interaction |
|
|---|
| Brite |
Drug groups [BR:br08330]
Cardiovascular agent
DG03231 Antihypertensive
DG01676 Aldosterone antagonist
D05912 Spiroxasone
DG01885 Potassium-sparing diuretic
D05912 Spiroxasone
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Estrogen like receptors
3-Ketosteroid receptor
NR3C2 (MR)
D05912 Spiroxasone (USAN/INN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 28
1 C1z C 46.1137 -16.4089
2 C1z C 44.9193 -17.0758
3 C1x C 47.2731 -17.1046
4 O2x O 47.2152 -15.6147
5 C1x C 45.0179 -15.6090
6 C1y C 44.9720 -18.4440
7 C1x C 43.7483 -16.3916
8 C1a C 44.2295 -15.5450
9 C1x C 47.2558 -18.3972
10 C1x C 46.8035 -14.2460
11 C1x C 45.4412 -14.3103
12 C1y C 43.7251 -19.1165
13 C1x C 42.5598 -17.0642
14 C1y C 42.5482 -18.4265
15 C1y C 43.7251 -20.4788
16 C1z C 41.3654 -19.1049
17 C1x C 42.5365 -21.1630
18 S2a S 44.9020 -21.1689
19 C2y C 41.3597 -20.4673
20 C1x C 40.1828 -18.4208
21 C1a C 41.3537 -17.7367
22 C5a C 46.0846 -20.4848
23 C2x C 40.1828 -21.1572
24 C1x C 38.9999 -19.1049
25 C1a C 47.2615 -21.1689
26 O5a O 46.0906 -19.1165
27 C5x C 38.9999 -20.4673
28 O5x O 37.8173 -21.1572
BOND 32
1 1 2 1
2 1 3 1
3 1 4 1 #Up
4 1 5 1 #Down
5 2 6 1
6 2 7 1
7 2 8 1 #Up
8 3 9 1
9 4 10 1
10 5 11 1
11 6 12 1
12 7 13 1
13 12 14 1
14 12 15 1
15 14 16 1
16 15 17 1
17 15 18 1 #Down
18 16 19 1
19 16 20 1
20 16 21 1 #Up
21 18 22 1
22 19 23 2
23 20 24 1
24 22 25 1
25 22 26 2
26 23 27 1
27 27 28 2
28 6 9 1
29 10 11 1
30 13 14 1
31 17 19 1
32 24 27 1
|
|---|
