KEGG   DRUG: Talopram hydrochloride
Entry
D05997                      Drug                                   
Name
Talopram hydrochloride (USAN)
Formula
C20H25NO. HCl
Exact mass
331.1703
Mol weight
331.88
Structure
Simcomp
Class
Neuropsychiatric agent
 DG03085  Selective norepinephrine reuptake inhibitor (NRI)
Efficacy
Potentiator (catecholamine), Selective noradrenaline reuptake inhibitor (NRI)
Target
SLC6A2 (NAT1) [HSA:6530] [KO:K05035]
  Pathway
hsa04721  Synaptic vesicle cycle
Interaction
Brite
Drug groups [BR:br08330]
 Neuropsychiatric agent
  DG03085  Selective norepinephrine reuptake inhibitor (NRI)
   D05997  Talopram hydrochloride
Target-based classification of drugs [BR:br08310]
 Transporters
  Solute carrier family
   SLC6
    SLC6A2 (NAT1)
     D05997  Talopram hydrochloride (USAN)
Other DBs
CAS: 7013-41-4
PubChem: 47207655
LigandBox: D05997
LinkDB
KCF data

ATOM        23
            1   C1z C    26.5440  -14.9375
            2   C8y C    25.2090  -14.5000
            3   O2x O    27.3778  -13.8063
            4   C1b C    27.9317  -14.9375
            5   C8y C    25.2147  -13.0950
            6   C8x C    24.0078  -15.1997
            7   C1z C    26.5557  -12.6635
            8   C1b C    28.6256  -16.1501
            9   C8x C    24.0078  -12.3954
            10  C8x C    22.7893  -14.4943
            11  C1b C    30.0247  -16.1501
            12  C8x C    22.7893  -13.0950
            13  N1b N    30.7244  -17.3628
            14  C1a C    32.1236  -17.3628
            15  C1a C    27.5456  -11.6736
            16  C1a C    25.5657  -11.6736
            17  C8y C    26.5440  -16.3375
            18  C8x C    25.3332  -17.0365
            19  C8x C    25.3332  -18.4365
            20  C8x C    26.5456  -19.1365
            21  C8x C    27.7564  -18.4375
            22  C8x C    27.7564  -17.0375
            23  X   Cl   32.2700  -14.0700
BOND        24
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     2   5 2
            5     2   6 1
            6     3   7 1
            7     4   8 1
            8     5   9 1
            9     6  10 2
            10    8  11 1
            11    9  12 2
            12   11  13 1
            13   13  14 1
            14    5   7 1
            15   10  12 1
            16    7  15 1
            17    7  16 1
            18    1  17 1
            19   17  18 2
            20   18  19 1
            21   19  20 2
            22   20  21 1
            23   21  22 2
            24   17  22 1

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