Entry |
|
Name |
Talopram hydrochloride (USAN) |
Formula |
C20H25NO. HCl
|
Exact mass |
331.1703
|
Mol weight |
331.88
|
Structure |
|
Simcomp |
|
Class |
Neuropsychiatric agent
DG03085 Selective norepinephrine reuptake inhibitor (NRI)
|
Efficacy |
Potentiator (catecholamine), Selective noradrenaline reuptake inhibitor (NRI) |
Target |
|
Pathway |
|
Interaction |
|
Brite |
Drug groups [BR:br08330]
Neuropsychiatric agent
DG03085 Selective norepinephrine reuptake inhibitor (NRI)
D05997 Talopram hydrochloride
Target-based classification of drugs [BR:br08310]
Transporters
Solute carrier family
SLC6
SLC6A2 (NAT1)
D05997 Talopram hydrochloride (USAN)
|
Other DBs |
|
LinkDB |
|
KCF data |
ATOM 23
1 C1z C 26.5440 -14.9375
2 C8y C 25.2090 -14.5000
3 O2x O 27.3778 -13.8063
4 C1b C 27.9317 -14.9375
5 C8y C 25.2147 -13.0950
6 C8x C 24.0078 -15.1997
7 C1z C 26.5557 -12.6635
8 C1b C 28.6256 -16.1501
9 C8x C 24.0078 -12.3954
10 C8x C 22.7893 -14.4943
11 C1b C 30.0247 -16.1501
12 C8x C 22.7893 -13.0950
13 N1b N 30.7244 -17.3628
14 C1a C 32.1236 -17.3628
15 C1a C 27.5456 -11.6736
16 C1a C 25.5657 -11.6736
17 C8y C 26.5440 -16.3375
18 C8x C 25.3332 -17.0365
19 C8x C 25.3332 -18.4365
20 C8x C 26.5456 -19.1365
21 C8x C 27.7564 -18.4375
22 C8x C 27.7564 -17.0375
23 X Cl 32.2700 -14.0700
BOND 24
1 1 2 1
2 1 3 1
3 1 4 1
4 2 5 2
5 2 6 1
6 3 7 1
7 4 8 1
8 5 9 1
9 6 10 2
10 8 11 1
11 9 12 2
12 11 13 1
13 13 14 1
14 5 7 1
15 10 12 1
16 7 15 1
17 7 16 1
18 1 17 1
19 17 18 2
20 18 19 1
21 19 20 2
22 20 21 1
23 21 22 2
24 17 22 1
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