| Entry |
|
|---|
| Name |
Tegaserod (USAN/INN) |
|---|
| Formula |
C16H23N5O
|
|---|
| Exact mass |
301.1903
|
|---|
| Mol weight |
301.39
|
|---|
| Structure |
|
|---|
| Class |
Gastrointestinal agent
DG01559 5-HT4-receptor antagonist
Metabolizing enzyme substrate
DG02924 UGT substrate
|
|---|
| Remark |
|
|---|
| Efficacy |
Prokinetic, Serotonin receptor agonist |
|---|
| Comment |
Treatment of gastrointestinal motility disorders
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Metabolism |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A06 DRUGS FOR CONSTIPATION
A06A DRUGS FOR CONSTIPATION
A06AX Other drugs for constipation
A06AX06 Tegaserod
D06056 Tegaserod (USAN/INN)
Drug groups [BR:br08330]
Gastrointestinal agent
DG01559 5-HT4-receptor antagonist
DG00081 Tegaserod
D06056 Tegaserod
Metabolizing enzyme substrate
DG02924 UGT substrate
DG00081 Tegaserod
D06056 Tegaserod
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Serotonin
HTR4
D06056 Tegaserod (USAN/INN)
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D06056
Drug groups [BR:br08330]
Gastrointestinal agent
DG01559 5-HT4-receptor antagonist
DG00081 Tegaserod
Metabolizing enzyme substrate
DG02924 UGT substrate
DG00081 Tegaserod
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 22
1 C8y C 23.6768 -13.7990
2 C8y C 21.4018 -13.7990
3 C8x C 23.6768 -15.1130
4 C8y C 21.4018 -15.1130
5 C8x C 20.2614 -13.1449
6 N4x N 22.5363 -15.7671
7 C8x C 20.2614 -15.7729
8 C8y C 19.1385 -13.7990
9 C8x C 19.1385 -15.1130
10 C2b C 24.9088 -13.1163
11 N2b N 26.1115 -13.8107
12 N1b N 27.3141 -13.1163
13 C2c C 28.5166 -13.8107
14 N1b N 29.7193 -13.1163
15 C1b C 30.9219 -13.8107
16 C1b C 32.1244 -13.1163
17 C1b C 33.3271 -13.8107
18 C1b C 34.5296 -13.1163
19 N2a N 28.5166 -15.1993
20 C1a C 35.7382 -13.8141
21 O2a O 17.9288 -13.1034
22 C1a C 16.7330 -13.7969
BOND 23
1 1 2 1
2 1 3 2
3 2 4 2
4 2 5 1
5 3 6 1
6 4 7 1
7 5 8 2
8 7 9 2
9 4 6 1
10 8 9 1
11 1 10 1
12 10 11 2
13 11 12 1
14 12 13 1
15 13 14 1
16 14 15 1
17 15 16 1
18 16 17 1
19 17 18 1
20 13 19 2
21 18 20 1
22 8 21 1
23 21 22 1
|
|---|
