KEGG   DGROUP: UGT substrate
Entry
DG02924                     DGroup                                 
Name
UGT substrate
Type
Metabolism
Member
UGT1A1 substrate
 D11051  
Vericiguat (JAN/USAN/INN)  <JP/US>
 D11441  
Aprocitentan (USAN/INN)  <US>
 DG00666  
Raltegravir
  D06676  
Raltegravir (INN)
  D07133  
Raltegravir potassium (JAN/USAN)  <JP/US>
 DG00667  
Dolutegravir
  D10066  
Dolutegravir (USAN)
  D10113  
Dolutegravir sodium (JAN/USAN)  <JP/US>
 DG01628  
Cabotegravir
  D10548  
Cabotegravir (JAN/USAN/INN)  <JP/US>
  D10549  
Cabotegravir sodium (JAN/USAN)  <JP/US>
 D10600  
Dolutegravir, abacavir and lamivudine  <JP/US>
 D11282  
Dolutegravir sodium and rilpivirine hydrochloride  <JP/US>
 DG03049  
Tecovirimat
  D09390  
Tecovirimat (USAN/INN)
  D11557  
Tecovirimat hydrate (JAN)  <US>
 DG03165  
Lenacapavir
  D12161  
Lenacapavir (USAN/INN)
  D12162  
Lenacapavir sodium (JAN/USAN)  <JP/US>
 DG00726  
Irinotecan
  D08086  
Irinotecan (INN)
  D01061  
Irinotecan hydrochloride (USP); Irinotecan hydrochloride hydrate (JP18)  <JP/US>
  D10642  
Irinotecan sucrosofate (USAN)
 DG01414  
Selumetinib
  D09666  
Selumetinib (USAN/INN)
  D10024  
Selumetinib sulfate (JAN/USAN)  <JP/US>
 D10985  
Sacituzumab govitecan (USAN/INN); Sacituzumab govitecan (genetical recombination) (JAN)  <JP/US>
 D08870  
Belinostat (USAN/INN)  <US>
 DG03207  
Iptacopan
  D12251  
Iptacopan (USAN/INN)
  D12252  
Iptacopan hydrochloride (USAN); Iptacopan hydrochloride hydrate (JAN)  <JP/US>
 DG01058  
Olodaterol
  D10145  
Olodaterol (USAN/INN)
  D10020  
Olodaterol hydrochloride (JAN/USAN)  <US>
 D03669  
Deferasirox (JAN/USAN/INN)  <JP/US>
 D11966  
Cabotegravir and rilpivirine  <US>
UGT1A3 substrate
 D10459  
Empagliflozin (JAN/USAN/INN)  <JP/US>
 D09994  
Selexipag (JAN/USAN/INN)  <JP/US>
 D11000  
Vamorolone (USAN/INN)  <US>
 DG01414  
Selumetinib
  D09666  
Selumetinib (USAN/INN)
  D10024  
Selumetinib sulfate (JAN/USAN)  <JP/US>
 DG03207  
Iptacopan
  D12251  
Iptacopan (USAN/INN)
  D12252  
Iptacopan hydrochloride (USAN); Iptacopan hydrochloride hydrate (JAN)  <JP/US>
 D03669  
Deferasirox (JAN/USAN/INN)  <JP/US>
UGT1A4 substrate
 D06273  
Imidafenacin (JAN/INN)  <JP>
 DG03049  
Tecovirimat
  D09390  
Tecovirimat (USAN/INN)
  D11557  
Tecovirimat hydrate (JAN)  <US>
 D10560  
Idelalisib (JAN/USAN/INN)  <US>
 DG02960  
Pexidartinib
  D11270  
Pexidartinib (USAN/INN)
  D11271  
Pexidartinib hydrochloride (JAN/USAN)  <US>
 D00354  
Lamotrigine (JAN/USP/INN)  <JP/US>
UGT1A7 substrate
 D10915  
Cannabidiol (JAN/USAN/INN)  <US>
 DG01058  
Olodaterol
  D10145  
Olodaterol (USAN/INN)
  D10020  
Olodaterol hydrochloride (JAN/USAN)  <US>
UGT1A8 substrate
 D10459  
Empagliflozin (JAN/USAN/INN)  <JP/US>
 DG03207  
Iptacopan
  D12251  
Iptacopan (USAN/INN)
  D12252  
Iptacopan hydrochloride (USAN); Iptacopan hydrochloride hydrate (JAN)  <JP/US>
UGT1A9 substrate
 D11066  
Ertugliflozin and sitagliptin  <US>
 DG00122  
Dapagliflozin
  D08897  
Dapagliflozin (JAN/USAN/INN)
  D09763  
Dapagliflozin propanediol (USAN); Dapagliflozin propylene glycolate hydrate (JAN)  <JP/US>
 D09592  
Canagliflozin (USAN/INN); Canagliflozin hydrate (JAN)  <JP/US>
 D10459  
Empagliflozin (JAN/USAN/INN)  <JP/US>
 DG02836  
Ertugliflozin
  D10313  
Ertugliflozin (USAN/INN)
  D11043  
Ertugliflozin pidolate  <US>
 D10669  
Sotagliflozin (USAN/INN)  <US>
 D10865  
Bexagliflozin (USAN)  <US>
 D10593  
Roxadustat (JAN/USAN/INN)  <JP>
 D11051  
Vericiguat (JAN/USAN/INN)  <JP/US>
 DG01628  
Cabotegravir
  D10548  
Cabotegravir (JAN/USAN/INN)  <JP/US>
  D10549  
Cabotegravir sodium (JAN/USAN)  <JP/US>
 DG00720  
Regorafenib
  D10138  
Regorafenib (USAN/INN)
  D10137  
Regorafenib hydrate (JAN)  <JP/US>
 D11817  
Deucravacitinib (JAN/USAN)  <JP/US>
 D10915  
Cannabidiol (JAN/USAN/INN)  <US>
 DG00956  
Viloxazine
  D08673  
Viloxazine (INN)
  D02572  
Viloxazine hydrochloride (USAN)  <US>
 DG01058  
Olodaterol
  D10145  
Olodaterol (USAN/INN)
  D10020  
Olodaterol hydrochloride (JAN/USAN)  <US>
 D10897  
Teneligliptin and canagliflozin  <JP>
 D11966  
Cabotegravir and rilpivirine  <US>
UGT2B4 substrate
 D09592  
Canagliflozin (USAN/INN); Canagliflozin hydrate (JAN)  <JP/US>
 DG00814  
Dihydrocodeine
  D07831  
Dihydrocodeine (INN)
  D01481  
Dihydrocodeine phosphate (JP18)  <JP>
  D03825  
Dihydrocodeine bitartrate (USP)
  D07832  
Dihydrocodeine thiocyanate
 D08695  
dl-Methylephedrine hydrochloride, dihydrocodeine phosphate, diprophylline, diphenhydramine salicylate, acetaminophen and bromovalerylurea  <JP>
 D11150  
Cenobamate (USAN/INN)  <US>
 DG01076  
Codeine
  C06174  
Codeine
  D00195  
Codeine (USP)
  D02101  
Codeine phosphate (USP); Codeine phosphate hydrate (JP18)  <JP>
  D03579  
Codeine polistirex (USAN)
  D03580  
Codeine sulfate (USP)  <US>
  D07740  
Codeine hydrochloride
 D12312  
Codeine phosphate and chlorpheniramine maleate  <US>
 D12313  
Chlorpheniramine polistirex and codeine polistirex
 D04313  
Dihydrocodeine phosphate, dl-methylephedrine hydrochloride and Chlorpheniramine maleate  <JP>
 D04338  
Dihydrocodeine phosphate, ephedrine hydrochloride and ammmonium chloride  <JP>
 D08697  
Platycodon fluidextract, glycyrrhiza extract, plantago herb extract, peony root extract and dihydrocodeine phosphate
 D10897  
Teneligliptin and canagliflozin  <JP>
 D11860  
Butalbital, aspirin, caffeine and codeine  <US>
 D11851  
Butalbital, acetaminophen, caffeine and codeine phosphate  <US>
UGT2B7 substrate
 D11066  
Ertugliflozin and sitagliptin  <US>
 D10459  
Empagliflozin (JAN/USAN/INN)  <JP/US>
 DG02836  
Ertugliflozin
  D10313  
Ertugliflozin (USAN/INN)
  D11043  
Ertugliflozin pidolate  <US>
 DG01248  
Ipragliflozin
  D10196  
Ipragliflozin (INN)
  D10200  
Ipragliflozin L-proline (JAN)  <JP>
 D09994  
Selexipag (JAN/USAN/INN)  <JP/US>
 D11441  
Aprocitentan (USAN/INN)  <US>
 D12047  
Drospirenone and estetrol  <JP/US>
 D11000  
Vamorolone (USAN/INN)  <US>
 DG03004  
Asciminib
  D11403  
Asciminib (USAN/INN)
  D11404  
Asciminib hydrochloride (JAN/USAN)  <JP/US>
 D11371  
Capivasertib (JAN/USAN)  <JP/US>
 DG00814  
Dihydrocodeine
  D07831  
Dihydrocodeine (INN)
  D01481  
Dihydrocodeine phosphate (JP18)  <JP>
  D03825  
Dihydrocodeine bitartrate (USP)
  D07832  
Dihydrocodeine thiocyanate
 D08695  
dl-Methylephedrine hydrochloride, dihydrocodeine phosphate, diprophylline, diphenhydramine salicylate, acetaminophen and bromovalerylurea  <JP>
 D10915  
Cannabidiol (JAN/USAN/INN)  <US>
 D11150  
Cenobamate (USAN/INN)  <US>
 D00365  
Lorazepam (JP18/USP/INN)  <JP/US>
 DG01058  
Olodaterol
  D10145  
Olodaterol (USAN/INN)
  D10020  
Olodaterol hydrochloride (JAN/USAN)  <US>
 DG01076  
Codeine
  C06174  
Codeine
  D00195  
Codeine (USP)
  D02101  
Codeine phosphate (USP); Codeine phosphate hydrate (JP18)  <JP>
  D03579  
Codeine polistirex (USAN)
  D03580  
Codeine sulfate (USP)  <US>
  D07740  
Codeine hydrochloride
 D12312  
Codeine phosphate and chlorpheniramine maleate  <US>
 D12313  
Chlorpheniramine polistirex and codeine polistirex
 D04313  
Dihydrocodeine phosphate, dl-methylephedrine hydrochloride and Chlorpheniramine maleate  <JP>
 D04338  
Dihydrocodeine phosphate, ephedrine hydrochloride and ammmonium chloride  <JP>
 D08697  
Platycodon fluidextract, glycyrrhiza extract, plantago herb extract, peony root extract and dihydrocodeine phosphate
 D11064  
Sitagliptin and ipragliflozin  <JP>
 D11860  
Butalbital, aspirin, caffeine and codeine  <US>
 D11851  
Butalbital, acetaminophen, caffeine and codeine phosphate  <US>
UGT2B15 substrate
 D00365  
Lorazepam (JP18/USP/INN)  <JP/US>
 DG00956  
Viloxazine
  D08673  
Viloxazine (INN)
  D02572  
Viloxazine hydrochloride (USAN)  <US>
UGT2B17 substrate
 D11000  
Vamorolone (USAN/INN)  <US>
 DG03004  
Asciminib
  D11403  
Asciminib (USAN/INN)
  D11404  
Asciminib hydrochloride (JAN/USAN)  <JP/US>
 D11954  
Belzutifan (JAN/USAN/INN)  <US>
Tegaserod
 D06056  
Tegaserod (USAN/INN)
 D02730  
Tegaserod maleate (USAN)
D01854  
Mitiglinide calcium hydrate (JP18)  <JP>
Milrinone
 D00417  
Milrinone (JAN/USP/INN)  <JP>
 D02085  
Milrinone lactate  <US>
Benazepril
 D07499  
Benazepril (INN)
 D00620  
Benazepril hydrochloride (JAN/USP)  <JP/US>
D00627  
Telmisartan (JP18/USP/INN)  <JP/US>
D10480  
Irbesartan and trichlormethiazide  <JP>
D09219  
Telmisartan and hydrochlorothiazide (JP18)  <JP/US>
D10805  
Telmisartan, amlodipine and hydrochlorothiazide  <JP>
D09743  
Telmisartan and amlodipine besilate (JP18)  <JP/US>
Fenofibrate
 D00565  
Fenofibrate (JP18/USP/INN)  <JP/US>
 D08890  
Choline fenofibrate (USAN/INN)  <US>
D01966  
Ezetimibe (JAN/USP/INN)  <JP/US>
D01965  
Silodosin (JP18/INN)  <JP/US>
D12137  
Elagolix, estradiol and norethisterone  <US>
Osilodrostat
 D11061  
Osilodrostat (USAN/INN)
 D11062  
Osilodrostat phosphate (JAN/USAN)  <JP/US>
D11521  
Lamivudine, nevirapine and zidovudine
Dasatinib
 D03658  
Dasatinib (JAN/INN)  <JP>
 D06414  
Dasatinib (USAN); Dasatinib hydrate (JAN)  <JP/US>
 D12609  
Dasatinib laurylsulfate (USAN)
Nintedanib
 D10481  
Nintedanib (USAN/INN)
 D10396  
Nintedanib esylate (USAN); Nintedanib ethanesulfonate (JAN)  <JP/US>
D06320  
Vorinostat (JAN/USAN)  <JP/US>
D11222  
Selinexor (USAN/INN)  <US>
Etrasimod
 D10930  
Etrasimod (USAN)
 D10931  
Etrasimod arginine (USAN); Etrasimod L-arginine (JAN)  <US>
Esketamine
 D07283  
Esketamine (USAN/INN)
 D10627  
Esketamine hydrochloride (JAN/USAN)  <US>
Morphine
 D08233  
Morphine (BAN)
 D00842  
Morphine sulfate (USP); Morphine sulfate hydrate (JP18)  <JP/US>
 D02271  
Morphine hydrochloride hydrate (JP18)  <JP>
 D08234  
Morphine tartrate
Hydromorphone
 D08047  
Hydromorphone (INN)
 D00839  
Hydromorphone hydrochloride (JAN/USP)  <JP/US>
Tapentadol
 D06007  
Tapentadol (USAN/INN)
 D10199  
Tapentadol hydrochloride (JAN)  <JP/US>
Desvenlafaxine
 D07793  
Desvenlafaxine (INN)  <US>
 D02570  
Desvenlafaxine succinate (USAN); Desvenlafaxine succinate hydrate (JAN)  <US>
 D11619  
Desvenlafaxine succinate anhydrous  <US>
Formoterol
 D07990  
Formoterol (INN)
 D01373  
Formoterol fumarate (USP)  <US>
 D05277  
Formoterol fumarate hydrate (JP18)  <JP/US>
D09595  
Budesonide and formoterol fumarate dihydrate  <JP/US>
D10506  
Fluticasone propionate and formoterol fumarate hydrate  <JP>
D11857  
Aclidinium bromide and formoterol fumarate  <US>
D10744  
Tiotropium and olodaterol  <JP/US>
D11520  
Ezetimibe and rosuvastatin  <JP>
 » expand
Class
Metabolizing enzyme substrate
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