KEGG   DRUG: Transcainide
Entry
D06203                      Drug                                   
Name
Transcainide (USAN/INN)
Formula
C22H35N3O2
Exact mass
373.2729
Mol weight
373.5322
Structure
Efficacy
Antiarrhythmic, Cardiac depressant, Sodium channel blocker
Target
SCN1A [HSA:6323] [KO:K04833]
SCN2A [HSA:6326] [KO:K04834]
SCN3A [HSA:6328] [KO:K04836]
SCN4A [HSA:6329] [KO:K04837]
SCN5A [HSA:6331] [KO:K04838]
SCN8A [HSA:6334] [KO:K04840]
SCN9A [HSA:6335] [KO:K04841]
SCN10A [HSA:6336] [KO:K04842]
SCN11A [HSA:11280] [KO:K04843]
  Pathway
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04728  Dopaminergic synapse
Brite
Target-based classification of drugs [BR:br08310]
 Ion channels
  Voltage-gated ion channels
   Sodium channels
    SCN1A
     D06203  Transcainide (USAN/INN)
    SCN2A
     D06203  Transcainide (USAN/INN)
    SCN3A
     D06203  Transcainide (USAN/INN)
    SCN4A
     D06203  Transcainide (USAN/INN)
    SCN5A
     D06203  Transcainide (USAN/INN)
    SCN8A
     D06203  Transcainide (USAN/INN)
    SCN9A
     D06203  Transcainide (USAN/INN)
    SCN10A
     D06203  Transcainide (USAN/INN)
    SCN11A
     D06203  Transcainide (USAN/INN)
Other DBs
CAS: 88296-62-2
PubChem: 47207861
LigandBox: D06203
NIKKAJI: J263.287J
LinkDB
KCF data

ATOM        27
            1   C1y C    28.6388  -19.5779
            2   C1y C    28.6277  -20.8956
            3   C1x C    29.7901  -21.5797
            4   C1x C    30.9637  -20.9151
            5   C1x C    30.9748  -19.5975
            6   C1x C    29.8125  -18.9134
            7   C8x C    18.9246  -16.8493
            8   C8x C    18.9246  -15.5005
            9   C8x C    20.0710  -14.8262
            10  C8y C    21.2849  -15.5005
            11  C8y C    21.2849  -16.8493
            12  C8y C    20.0710  -17.5237
            13  C1a C    20.0710  -18.8724
            14  C1a C    22.4314  -14.8262
            15  N1b N    22.5662  -17.5237
            16  C5a C    23.8746  -16.8588
            17  C1z C    25.1477  -17.5285
            18  C1x C    25.1366  -18.8724
            19  C1x C    26.2990  -19.5565
            20  N1y N    27.5427  -18.8917
            21  C1x C    27.4837  -17.5478
            22  C1x C    26.3213  -16.8637
            23  N1c N    25.1477  -14.9658
            24  C1a C    26.3036  -14.2983
            25  C1a C    23.9635  -14.2821
            26  O1a O    27.4600  -21.5568
            27  O5a O    23.8844  -15.4701
BOND        29
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     7   8 2
            8     8   9 1
            9     9  10 2
            10   10  11 1
            11   11  12 2
            12    7  12 1
            13   12  13 1
            14   10  14 1
            15   11  15 1
            16   15  16 1
            17   16  17 1
            18   17  18 1
            19   18  19 1
            20   19  20 1
            21   20  21 1
            22   21  22 1
            23   17  22 1
            24   17  23 1
            25   23  24 1
            26   23  25 1
            27    1  20 1 #Down
            28    2  26 1 #Up
            29   16  27 2

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