KEGG   DRUG: TropatepineHelp
Entry
D07303                      Drug                                   

Name
Tropatepine (INN)
Formula
C22H23NS
Exact mass
333.1551
Mol weight
333.4897
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Neuropsychiatric agent
 DG01745  Anticholinergic antiparkinson agent
 DG01967  Antiparkinson agent
  DG01745  Anticholinergic antiparkinson agent
Remark
ATC code: N04AA12
Chemical structure group: DG00858
Efficacy
Antiparkinsonian, Muscarinic acetylcholine receptor antagonist
Comment
Atropine [CPD:C01479] derivative; Tricyclic compound
Target
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N04 ANTI-PARKINSON DRUGS
   N04A ANTICHOLINERGIC AGENTS
    N04AA Tertiary amines
     N04AA12 Tropatepine
      D07303  Tropatepine (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    CHRM
     D07303  Tropatepine (INN)
BRITE hierarchy
Other DBs
CAS: 27574-24-9
PubChem: 51091640
LigandBox: D07303
NIKKAJI: J9.902C
LinkDB All DBs
KCF data Show

ATOM        24
            1   C1x C    18.6962  -14.3526
            2   C1x C    19.0024  -13.2398
            3   C1y C    19.8328  -13.9227
            4   C1y C    20.2091  -12.8099
            5   N1y N    19.0672  -11.4337
            6   C1x C    21.6212  -13.9242
            7   C1x C    21.4013  -12.7876
            8   C2y C    22.5935  -14.4939
            9   C1a C    18.3836  -10.2786
            10  C2y C    22.5781  -15.9545
            11  C8y C    23.7595  -16.5475
            12  C8y C    24.0416  -17.8435
            13  S2x S    23.2091  -18.8634
            14  C8y C    21.3700  -16.5210
            15  C1x C    21.8808  -18.8576
            16  C8y C    21.0643  -17.8114
            17  C8x C    20.4056  -15.6113
            18  C8x C    19.1356  -15.9916
            19  C8x C    18.8298  -17.2820
            20  C8x C    19.7943  -18.1918
            21  C8x C    25.3043  -18.2471
            22  C8x C    26.2854  -17.3552
            23  C8x C    26.0034  -16.0593
            24  C8x C    24.7405  -15.6557
BOND        28
            1     1   2 1
            2     1   3 1
            3     2   4 1
            4     3   5 1
            5     3   6 1
            6     4   7 1
            7     6   8 1
            8     4   5 1
            9     7   8 1
            10    5   9 1
            11   12  13 1
            12   10  14 1
            13   13  15 1
            14   11  12 1
            15   14  16 1
            16   10  11 1
            17   15  16 1
            18   14  17 2
            19   17  18 1
            20   18  19 2
            21   19  20 1
            22   16  20 2
            23   12  21 2
            24   21  22 1
            25   22  23 2
            26   23  24 1
            27   11  24 2
            28    8  10 2

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