KEGG   DRUG: PiribedilHelp
Entry
D07305                      Drug                                   

Name
Piribedil (INN);
Trivastal (TN)
Formula
C16H18N4O2
Exact mass
298.143
Mol weight
298.3397
Structure
Mol fileKCF fileDB search
Class
Cardiovascular agent
 DG01466  Adrenergic receptor antagonist
  DG01465  alpha-Adrenergic receptor antagonist
   DG01460  alpha2-Adrenergic receptor antagonist
Neuropsychiatric agent
 DG01472  Dopamine agonist
  DG01468  Dopamine D2-receptor agonist
  DG01469  Dopamine D3-receptor agonist
 DG01967  Antiparkinson agent
Remark
ATC code: N04BC08
Efficacy
Antiparkinsonian, Dopamine receptor agonist
Target
DRD2 [HSA:1813] [KO:K04145]
DRD3 [HSA:1814] [KO:K04146]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04728  Dopaminergic synapse
Interaction
Drug interaction
Structure map
map07057  Antiparkinsonian agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N04 ANTI-PARKINSON DRUGS
   N04B DOPAMINERGIC AGENTS
    N04BC Dopamine agonists
     N04BC08 Piribedil
      D07305  Piribedil (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Dopamine
    DRD2
     D07305  Piribedil (INN)
    DRD3
     D07305  Piribedil (INN)
BRITE hierarchy
Other DBs
CAS: 3605-01-4
PubChem: 51091642
ChEMBL: CHEMBL1371770
LigandBox: D07305
NIKKAJI: J8.178G
LinkDB All DBs
KCF data Show

ATOM        22
            1   C1x C    14.4200  -16.8700
            2   N1y N    14.4200  -18.2700
            3   C1x C    15.6324  -18.9700
            4   C1x C    16.8449  -18.2700
            5   N1y N    16.8449  -16.8700
            6   C1x C    15.6324  -16.1700
            7   C1b C    18.0760  -16.1590
            8   C8y C    19.2811  -16.8547
            9   C8x C    19.2816  -18.2696
            10  C8x C    20.4942  -18.9693
            11  C8y C    21.7064  -18.2689
            12  C8y C    21.7060  -16.8540
            13  C8x C    20.4934  -16.1543
            14  O2x O    23.0523  -18.7058
            15  C1x C    23.8836  -17.5608
            16  O2x O    23.0516  -16.4163
            17  C8y C    13.2076  -18.9700
            18  N5x N    12.0121  -18.2796
            19  C8x C    10.7996  -18.9794
            20  C8x C    10.7994  -20.3794
            21  C8x C    11.9949  -21.0698
            22  N5x N    13.2074  -20.3700
BOND        25
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     5   7 1
            8     7   8 1
            9     8   9 2
            10    9  10 1
            11   10  11 2
            12   11  12 1
            13   12  13 2
            14    8  13 1
            15   11  14 1
            16   14  15 1
            17   15  16 1
            18   12  16 1
            19    2  17 1
            20   17  18 2
            21   18  19 1
            22   19  20 2
            23   20  21 1
            24   21  22 2
            25   17  22 1

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