KEGG ORTHOLOGY: K04146

ORTHOLOGY: K04146

Entry

K04146                      KO

Symbol

DRD3

Name

dopamine receptor D3

Pathway

map04080

Neuroactive ligand-receptor interaction

map04081

Hormone signaling

map04082

Neuroactive ligand signaling

map04728

Dopaminergic synapse

Disease

H01577

Essential tremor

H01649

Schizophrenia

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04146  DRD3; dopamine receptor D3
   04082 Neuroactive ligand signaling
    K04146  DRD3; dopamine receptor D3
   04081 Hormone signaling
    K04146  DRD3; dopamine receptor D3
09150 Organismal Systems
  09156 Nervous system
   04728 Dopaminergic synapse
    K04146  DRD3; dopamine receptor D3
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04146  DRD3; dopamine receptor D3
G protein-coupled receptors [BR:ko04030]
Rhodopsin family
  Biogenic amine
   Dopamine
    K04146  DRD3; dopamine receptor D3

Other DBs

GO:

0001591

TC:	9.A.14.3.9

Genes

HSA:	1814(DRD3)

PTR:	470885(DRD3)

PPS:	100984609(DRD3)

GGO:	101132878(DRD3)

PON:	100454395(DRD3)

PPYG:

129033792(DRD3)

NLE:	100594342(DRD3)

HMH:	116466316(DRD3)

SSYN:

129471262(DRD3)

MCC:	100425047(DRD3)

MCF:	102123487(DRD3)

MTHB:

126949262

MNI:	105470374(DRD3)

CSAB:

103228289(DRD3)

CATY:

105596287(DRD3)

PANU:

101009027(DRD3)

TGE:	112618986(DRD3)

MLEU:

105529632(DRD3)

RRO:	104660606(DRD3)

RBB:	108519483(DRD3)

TFN:	117076621(DRD3)

PTEH:

111541871(DRD3)

CANG:

105510704(DRD3)

CJC:	100398788(DRD3)

SBQ:	101037836(DRD3)

CIMI:

108317405

ANAN:

105725000(DRD3)

CSYR:

103268304(DRD3)

MMUR:

105883933(DRD3)

LCAT:

123642077(DRD3)

PCOQ:

105816746(DRD3)

OGA:	100959253(DRD3)

MMU:	13490(Drd3)

MCAL:

110311792(Drd3)

MPAH:

110329875(Drd3)

RNO:	29238(Drd3)

MCOC:

116086417(Drd3)

ANU:	117718078(Drd3)

ASYL:

127666035(Drd3)

MUN:	110557780(Drd3)

CGE:	100769070(Drd3)

MAUA:

101836535(Drd3)

PROB:

127227182(Drd3)

PLEU:

114694979(Drd3)

MORG:

121461963(Drd3)

MFOT:

126505783

AAMP:

119825223(Drd3)

NGI:	103741932(Drd3)

HGL:	101713857(Drd3)

CPOC:

100716075(Drd3)

CCAN:

109678247(Drd3)

DORD:

105994896(Drd3)

DSP:	122105576(Drd3)

PLOP:

125351292(Drd3)

NCAR:

124993306

MMMA:

107136186(Drd3)

ITI:	101970464(Drd3)

OCU:

100343485

OPI:	101517452(DRD3)

TUP:	102483861(DRD3)

GVR:	103596516(DRD3)

CFA:	487984(DRD3)

CLUD:

112678084(DRD3)

VVP:	112913445(DRD3)

VLG:	121501338(DRD3)

NPO:	129503916(DRD3)

AML:	100474054(DRD3)

UMR:	103678807(DRD3)

UAH:	113256431(DRD3)

UAR:	123784294(DRD3)

ELK:

111150975

LLV:

125078618

MPUF:

101690016(DRD3)

MNP:	132010189(DRD3)

MLK:	131825114(DRD3)

NVS:	122910426(DRD3)

ORO:	101368111(DRD3)

EJU:	114214824(DRD3)

ZCA:	113917541(DRD3)

MLX:	118000626(DRD3)

NSU:	110582507(DRD3)

LWW:	102738050(DRD3)

FCA:	101092878(DRD3)

PYU:	121036262(DRD3)

PCOO:

112849609(DRD3)

PBG:	122491463(DRD3)

PVIV:

125174774(DRD3)

LRUF:

124526951

LGF:	123610903(DRD3)

AJU:

106977772

PTG:	102956080(DRD3)

PPAD:

109266419(DRD3)

PUC:

125921764

PLEZ:

122230277(DRD3)

HHV:	120226664(DRD3)

BTA:	537043(DRD3)

BOM:	102280251(DRD3)

BIU:	109564092(DRD3)

BBUB:

102413222(DRD3)

BBIS:

104992461(DRD3)

CHX:	102188084(DRD3)

OAS:	101103110(DRD3)

BTAX:

128054403(DRD3)

CSUM:

138084583(DRD3)

ODA:	120851621(DRD3)

CCAD:

122445563(DRD3)

MREE:

136173475(DRD3)

MBEZ:

129550589(DRD3)

SSC:	100513049(DRD3)

CFR:	102519907(DRD3)

CBAI:

105081577(DRD3)

CDK:	105093194(DRD3)

VPC:	102543321(DRD3)

BACU:

103008846(DRD3)

BMUS:

118894684(DRD3)

LVE:	103075834(DRD3)

OOR:	101290463(DRD3)

LALB:

132520597(DRD3)

DLE:	111175367(DRD3)

PCAD:

102976222(DRD3)

PSIU:

116753273(DRD3)

NASI:

112393245(DRD3)

ECB:	100061160(DRD3)

EPZ:	103552929(DRD3)

EAI:	106829519(DRD3)

MYB:	102259828(DRD3)

MYD:	102756066(DRD3)

MMYO:

118676717(DRD3)

MLF:	102417311(DRD3)

MDT:	132229270(DRD3)

MYUM:

139002160(DRD3)

PKL:	118724413(DRD3)

EFUS:

103290699(DRD3)

MNA:	107527386(DRD3)

DRO:	112320584(DRD3)

SHON:

118994705(DRD3)

AJM:	119043035(DRD3)

PDIC:

114490900(DRD3)

PHAS:

123827280(DRD3)

MMF:	118617453(DRD3)

PPAM:

129073658(DRD3)

HAI:	109387959(DRD3)

RFQ:	117037768(DRD3)

PALE:

102878121(DRD3)

PGIG:

120586623(DRD3)

PVP:	105303360(DRD3)

RAY:	107513697(DRD3)

MJV:	108392279(DRD3)

TOD:	119256822(DRD3)

SARA:

101540729(DRD3)

SFUM:

130018626(DRD3)

SETR:

126026070(DRD3)

LAV:	100676993(DRD3)

TMU:

101353801

ETF:	101651277(DRD3)

DNM:	101429338(DRD3)

MDO:	100014112(DRD3)

GAS:	123239489(DRD3)

SHR:	100913402(DRD3)

AFZ:

127554085

PCW:	110222242(DRD3)

TVP:	118839162(DRD3)

PBRV:

138147515(DRD3)

GGA:	770757(DRD3)

PCOC:

116242389(DRD3)

MGP:	100549401(DRD3)

CJO:	107320208(DRD3)

TPAI:

128091532(DRD3)

LMUT:

125687975(DRD3)

NMEL:

110399597(DRD3)

APLA:

101799559(DRD3)

ACYG:

106037929(DRD3)

CATA:

118245002(DRD3)

AFUL:

116496915(DRD3)

TGU:	100190794(DRD3)

LSR:	110480696(DRD3)

SCAN:

103827090(DRD3)

PMOA:

120506415(DRD3)

OTC:	121339260(DRD3)

PRUF:

121351608(DRD3)

ATRC:

139592924(DRD3)

GFR:	102032767(DRD3)

FAB:	101806210(DRD3)

OMA:	130252511(DRD3)

PHI:	102110328(DRD3)

PMAJ:

107203499(DRD3)

CCAE:

111939296(DRD3)

CCW:	104687064(DRD3)

CBRC:

103614024(DRD3)

ACOE:

138112754(DRD3)

ETL:	114055119(DRD3)

ZAB:	102073117(DRD3)

ZLE:	135452159(DRD3)

ACHL:

103799605(DRD3)

SVG:	106854569(DRD3)

MMEA:

130572495(DRD3)

HRT:	120749547(DRD3)

SATI:

136375443(DRD3)

CCIC:

134056110(DRD3)

FPG:	101922369(DRD3)

FCH:	102052693(DRD3)

CCRI:

104169578(DRD3)

NNT:	104401305(DRD3)

SHAB:

115601555(DRD3)

ACUN:

113485051(DRD3)

TALA:

104368708(DRD3)

ACHC:

115343711(DRD3)

HALD:

104311002(DRD3)

HLE:	104831685(DRD3)

AGEN:

126049109

HHAR:

128144906(DRD3)

GCL:

127015651

CSTI:

104553292(DRD3)

LDI:	104344111(DRD3)

MNB:	103775934(DRD3)

DPUB:

104307061(DRD3)

PPUS:

135175324(DRD3)

AVIT:

104275531(DRD3)

BRHI:

104496577(DRD3)

EGZ:	104126235(DRD3)

NNI:	104014076(DRD3)

PCRI:

104025009(DRD3)

PCAO:

104047537

PADL:

103921515(DRD3)

AFOR:

103907478(DRD3)

FGA:	104073739(DRD3)

GSTE:

104254693(DRD3)

CLV:	102095168(DRD3)

MUI:	104537666(DRD3)

PGUU:

104470573(DRD3)

PLET:

104616237(DRD3)

EHS:	104517208(DRD3)

CMAC:

104476590

CUCA:

104055797(DRD3)

TEO:	104370418(DRD3)

BREG:

104634337(DRD3)

OHA:	104333898(DRD3)

ACAR:

104518562(DRD3)

CPEA:

104389267(DRD3)

CVF:	104281862(DRD3)

RTD:	128914726(DRD3)

CRID:

134522960(DRD3)

AAM:	106490539(DRD3)

AROW:

112974038(DRD3)

NPD:	112945579(DRD3)

TGT:	104571920(DRD3)

DNE:	112979639(DRD3)

SCAM:

104144268(DRD3)

ASN:	102386496(DRD3)

AMJ:	102576256(DRD3)

CPOO:

109319311(DRD3)

GGN:	109304870(DRD3)

PSS:	102451549(DRD3)

CMY:	102938985(DRD3)

CCAY:

125621289(DRD3)

DCC:	119861431(DRD3)

CPIC:

101942822(DRD3)

TST:	117871033(DRD3)

CABI:

116822763(DRD3)

MRV:	120373112(DRD3)

ACS:	100556183(drd3)

ASAO:

132772070(DRD3)

PVT:	110084757(DRD3)

SUND:

121926367(DRD3)

PBI:	103054341(DRD3)

PMUR:

107288264(DRD3)

VKO:	123029343(DRD3)

PMUA:

114595824(DRD3)

PRAF:

128412765(DRD3)

ZVI:	118078335 118084770(DRD3)

HCG:	128348861(DRD3)

GJA:	107112443(DRD3)

STOW:

125430434(DRD3)

EMC:	129326051(DRD3)

PWL:	138248785(DRD3)

MUO:	115471328(DRD3)

GSH:	117359702(DRD3)

DRE:	282554(drd3)

SRX:	107733056 107754942

SANH:

107654199 107701643

SGH:	107585015 107591280

CCAR:

109058564(drd3)

CAUA:

113042725 113065960

CGIB:

127945900 128012933

PTET:

122330234(drd3)

LROH:

127155373(drd3)

OMC:	131533217(drd3)

PPRM:

120476053(drd3)

RKG:	130083855(drd3)

MAMB:

125258403(drd3)

CIDE:

127506501

CERY:

137013596(drd3)

MASI:

127432042 127434797

TROS:

130547402(drd3)

TDW:	130413329(drd3)

MANU:

129426282(drd3)

PDAB:

135740556(drd3)

IPU:

108256204

IFU:	128599968(drd3)

PHYP:

113541240(drd3)

SMEO:

124375668(drd3)

TFD:	113661610(drd3)

TVC:	132840188(drd3)

CGAR:

128514147(drd3)

NGRA:

132867900(drd3)

TRN:	134300905(drd3)

AMEX:

103024755(drd3)

CMAO:

118798772(drd3) 118814062

EEE:

113581235

CHAR:

105890089(drd3)

SPIL:

134066111(drd3)

TRU:	101061574(drd3)

TFS:	130513955(drd3)

TNG:	GSTEN00023894G001

LCO:	104934476(drd3)

TBEN:

117493955 117498753(drd3)

CGOB:

115025762 115025802

PGEO:

117449333 117465506(drd3)

GACU:

117535851(drd3)

EMAC:

134883769(drd3)

ELY:	117264462(drd3)

EFO:	125882182(drd3)

PLEP:

121960747(drd3)

SLUC:

116037971(drd3)

ECRA:

117937613(drd3)

ESP:	116672402(drd3)

PFLV:

114549091(drd3)

GAT:	120811924(drd3)

PPUG:

119198815(drd3)

AFB:	129110842(drd3)

CLUM:

117749578(drd3)

PSWI:

130206158(drd3)

CANA:

137788653(drd3)

CVE:	137888798(drd3)

MSAM:

119910027(drd3)

SCHU:

122866291(drd3)

CUD:	121527436(drd3)

SPUL:

138595754(drd3)

LMIX:

132994470(drd3)

ALAT:

119008825(drd3)

ASTR:

137587612(drd3)

MZE:	101466511(drd3)

ONL:	100700994(drd3)

OAU:	116314531(drd3)

OLA:	101163209(drd3)

OML:	112151030(drd3)

CSAI:

133422967(drd3)

XHE:	116712258(drd3)

PFOR:

103139760(drd3)

PLAI:

106944641(drd3)

PMEI:

106909294(drd3)

GAF:	122824330(drd3)

PPRL:

129364818(drd3)

CTUL:

119778832

GMU:	124858480(drd3)

NFU:	107382847(drd3)

KMR:	108230287(drd3)

ALIM:

106513406(drd3)

NWH:	119426580(drd3)

AOCE:

111565955(drd3) 111572874

EJA:	138192603 138204279(drd3)

BFRE:

138623835(drd3) 138637188

MCEP:

125024391(drd3)

CSEM:

103377231(drd3)

POV:	109629576(drd3)

SSEN:

122775385(drd3)

HHIP:

117753862(drd3)

HSP:	118098946(drd3)

PPLT:

128425812(drd3)

SMAU:

118290884(drd3)

LCF:

108881734

SDU:	111220952(drd3)

SLAL:

111662989(drd3)

XGL:	120790149(drd3)

HCQ:	109514061(drd3)

SSCV:

125985745(drd3)

SBIA:

133492796(drd3) 133494432

PEE:	133396585(drd3)

PTAO:

133470413(drd3) 133490028

BPEC:

110160994(drd3)

ENY:	140364617(drd3)

MALB:

109960079(drd3)

BSPL:

114853454(drd3) 114853455 114853483

SJO:	128382310(drd3)

SSCO:

134002204(drd3)

GMH:	115537645(drd3) 115547878

SASA:

106579486 106590468

STRU:

115151465 115195266

OTW:	112216544 112252992

OMY:	110490825 110535364(drd3)

OGO:	123990248(drd3) 124039126

ONE:	115104498 115131083

OKI:	109900139 109909731

OKE:	118373642(drd3) 118382487

OMM:	135518523 135523195(drd3)

OCLA:

139366707 139420642

SALP:

111973273

SNH:	120028047(drd3) 120050963

CCLU:

121549504(drd3) 121569272

ELS:	105021975(drd3)

OEP:	134035372(drd3)

PKI:	111860966(drd3)

CCOG:

133134464

LOC:	102695188(drd3)

PSPA:

121302597(drd3)

ARUT:

117406286 117972721

PSEX:

120523110(drd3)

LCM:

102359087

CMK:	103183539(drd3)

RTP:	109921251(drd3)

CPLA:

122555031(drd3)

HOC:	132820718(drd3)

LERI:

129702615(drd3)

AJJ:

139980202

ARUN:

117290086 117295058 117303361

AAMU:

139940752 139948412

AFIL:

140154352 140154353 140156577 140157018

PFLL:

PCLA:

ESN:

LPOL:

LSAX:

BGT:

GAE:

MMER:

123540381 123554373 123555479

RPHI:

132720326 132723551

LJP:	135467358 135475064

ATEN:

116300804 116304932

MFOO:

138008751

SPIS:

111330923

XEN:	124435718 124454146

» show all

Reference

PMID:19520868

Authors

Villar VA, Jones JE, Armando I, Palmes-Saloma C, Yu P, Pascua AM, Keever L, Arnaldo FB, Wang Z, Luo Y, Felder RA, Jose PA

Title

G protein-coupled receptor kinase 4 (GRK4) regulates the phosphorylation and function of the dopamine D3 receptor.

Journal

J Biol Chem 284:21425-34 (2009)
DOI:10.1074/jbc.M109.003665

Sequence

[hsa:1814]

Reference

PMID:8415635

Authors

Schmauss C, Haroutunian V, Davis KL, Davidson M

Title

Selective loss of dopamine D3-type receptor mRNA expression in parietal and motor cortices of patients with chronic schizophrenia.

Journal

Proc Natl Acad Sci U S A 90:8942-6 (1993)
DOI:10.1073/pnas.90.19.8942

Sequence

[hsa:1814]

LinkDB

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