Homo sapiens (human): 1814
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Entry
1814 CDS
T01001
Symbol
DRD3, D3DR, ETM1, FET1
Name
(RefSeq) dopamine receptor D3
KO
K04146
dopamine receptor D3
Organism
hsa
Homo sapiens (human)
Pathway
hsa04080
Neuroactive ligand-receptor interaction
hsa04081
Hormone signaling
hsa04728
Dopaminergic synapse
Disease
H01577
Essential tremor
H01649
Schizophrenia
Drug target
Amisulpride:
D07310
<US>
Aplindore fumarate:
D03214
Aripiprazole (
DG00906
):
D01164
<JP/US>
D10355
D10364
<US>
D10516
<JP/US>
Blonanserin:
D01176
<JP>
Captodiame:
D07316
Dexpramipexole (
DG01331
):
D09886
D09887
Dopamine (
DG00213
):
D00633
<JP/US>
D07870
Dopexamine (
DG00222
):
D03891
D03892
Etilevodopa:
D04097
Foslevodopa:
D11839
Levodopa:
D00059
<JP/US>
Lisuride (
DG00453
):
D01462
D08132
Olanzapine (
DG00898
):
D00454
<JP/US>
D06623
<US>
Oxiperomide:
D02676
Pardoprunox (
DG01324
):
D09366
D09397
Piribedil:
D07305
Pramipexole (
DG00863
):
D00559
<JP/US>
D05575
Quinpirole hydrochloride:
D05682
Ropinirole (
DG00862
):
D00784
<JP/US>
D08489
Tiotixene (
DG00895
):
D00374
<US>
D02612
Trazpiroben:
D11982
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09133 Signaling molecules and interaction
04080 Neuroactive ligand-receptor interaction
1814 (DRD3)
04081 Hormone signaling
1814 (DRD3)
09150 Organismal Systems
09156 Nervous system
04728 Dopaminergic synapse
1814 (DRD3)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04030 G protein-coupled receptors [BR:
hsa04030
]
1814 (DRD3)
G protein-coupled receptors [BR:
hsa04030
]
Rhodopsin family
Biogenic amine
Dopamine
1814 (DRD3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
7tm_1
7TM_GPCR_Srsx
7TM_GPCR_Srx
7tm_4
Motif
Other DBs
NCBI-GeneID:
1814
NCBI-ProteinID:
NP_000787
OMIM:
126451
HGNC:
3024
Ensembl:
ENSG00000151577
UniProt:
P35462
A8K8E4
X5D2G4
Structure
PDB
PDBj
LinkDB
All DBs
Position
3:complement(114127580..114199407)
Genome browser
AA seq
400 aa
AA seq
DB search
MASLSQLSGHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
NT seq
1203 nt
NT seq
+upstream
nt +downstream
nt
atggcatctctgagccagctgagtggccacctgaactacacctgtggggcagagaactcc
acaggtgccagccaggcccgcccacatgcctactatgccctctcctactgcgcgctcatc
ctggccatcgtcttcggcaatggcctggtgtgcatggctgtgctgaaggagcgggccctg
cagactaccaccaactacttagtagtgagcctggctgtggcagacttgctggtggccacc
ttggtgatgccctgggtggtatacctggaggtgacaggtggagtctggaatttcagccgc
atttgctgtgatgtttttgtcaccctggatgtcatgatgtgtacagccagcatccttaat
ctctgtgccatcagcatagacaggtacactgcagtggtcatgcccgttcactaccagcat
ggcacgggacagagctcctgtcggcgcgtggccctcatgatcacggccgtctgggtactg
gcctttgctgtgtcctgccctcttctgtttggctttaataccacaggggaccccactgtc
tgctccatctccaaccctgattttgtcatctactcttcagtggtgtccttctacctgccc
tttggagtgactgtccttgtctatgccagaatctatgtggtgctgaaacaaaggagacgg
aaaaggatcctcactcgacagaacagtcagtgcaacagtgtcaggcctggcttcccccag
caaaccctctctcctgacccggcacatctggagctgaagcgttactacagcatctgccag
gacactgccttgggtggaccaggcttccaagaaagaggaggagagttgaaaagagaggag
aagactcggaattccctgagtcccaccatagcgcccaagctcagcttagaagttcgaaaa
ctcagcaatggcagattatcgacatctttgaagctggggcccctgcaacctcggggagtg
ccacttcgggagaagaaggcaacccaaatggtggccattgtgcttggggccttcattgtc
tgctggctgcccttcttcttgacccatgttctcaatacccactgccagacatgccacgtg
tccccagagctttacagtgccacgacatggctgggctacgtgaatagcgccctcaaccct
gtgatctataccaccttcaatatcgagttccggaaagccttcctcaagatcctgtcttgc
tga
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