KEGG   DRUG: AfelimomabHelp
Entry
D07436                      Drug                                   

Name
Afelimomab (INN)
Class
Other
 DG01936  TNF inhibitor
Remark
ATC code: L04AB03
Efficacy
Immunosuppressant, Anti-TNF-alpha antibody
Comment
Monoclonal antibody
Target
TNF (TNFA, TNFSF2) [HSA:7124] [KO:K03156]
  Pathway
hsa04010  MAPK signaling pathway
hsa04060  Cytokine-cytokine receptor interaction
hsa04210  Apoptosis
hsa04350  TGF-beta signaling pathway
hsa04612  Antigen processing and presentation
hsa04920  Adipocytokine signaling pathway
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L04 IMMUNOSUPPRESSANTS
   L04A IMMUNOSUPPRESSANTS
    L04AB Tumor necrosis factor alpha (TNF-alpha) inhibitors
     L04AB03 Afelimomab
      D07436  Afelimomab (INN)
Target-based classification of drugs [BR:br08310]
 Cytokines and receptors
  Cytokines
   Tumor necrosis factors
    TNF (TNFA, TNFSF2)
     D07436  Afelimomab (INN)
BRITE hierarchy
Other DBs
CAS: 156227-98-4
PubChem: 51091768
LinkDB All DBs

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