KEGG   DRUG: AmfepramoneHelp
Entry
D07444                      Drug                                   

Name
Amfepramone (INN);
Diethylpropion (BAN)
Formula
C13H19NO
Exact mass
205.1467
Mol weight
205.2961
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Other
 DG01706  Antiobesity
  DG01705  Anoretic
   DG01704  Phenethylamine anorexic
Remark
Same as: C06954
ATC code: A08AA03
Chemical structure group: DG00104
Product (DG00104): D03801<US>
Efficacy
Appetite suppressant
Target
SLC6A2 (NAT1) [HSA:6530] [KO:K05035]
SLC6A3 (DAT1) [HSA:6531] [KO:K05036]
  Pathway
hsa04728  Dopaminergic synapse
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A08 ANTIOBESITY PREPARATIONS, EXCL. DIET PRODUCTS
   A08A ANTIOBESITY PREPARATIONS, EXCL. DIET PRODUCTS
    A08AA Centrally acting antiobesity products
     A08AA03 Amfepramone
      D07444  Amfepramone (INN)
Target-based classification of drugs [BR:br08310]
 Transporters
  Solute carrier family
   SLC6
    SLC6A2 (NAT1)
     D07444  Amfepramone (INN)
    SLC6A3 (DAT1)
     D07444  Amfepramone (INN)
BRITE hierarchy
Other DBs
CAS: 90-84-6
PubChem: 51091775
ChEBI: 4530
ChEMBL: CHEMBL1194666
LigandBox: D07444
NIKKAJI: J4.327C
LinkDB All DBs
KCF data Show

ATOM        15
            1   C8y C    16.8000  -16.5200
            2   C5a C    17.9900  -15.8200
            3   C8x C    15.6100  -15.8200
            4   C8x C    16.8000  -17.9200
            5   C1c C    19.2500  -16.5200
            6   O5a O    17.9900  -14.4200
            7   C8x C    14.3500  -16.5200
            8   C8x C    15.6100  -18.6200
            9   N1c N    20.4400  -15.8200
            10  C1a C    19.2500  -17.9200
            11  C8x C    14.3500  -17.9200
            12  C1b C    21.6300  -16.5200
            13  C1b C    20.4400  -14.4200
            14  C1a C    22.8900  -15.8200
            15  C1a C    21.6300  -13.7200
BOND        15
            1     1   2 1
            2     1   3 2
            3     1   4 1
            4     2   5 1
            5     2   6 2
            6     3   7 1
            7     4   8 2
            8     5   9 1
            9     5  10 1
            10    7  11 2
            11    9  12 1
            12    9  13 1
            13   12  14 1
            14   13  15 1
            15    8  11 1

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