| Entry |
|
|---|
| Name |
Amiloride (INN);
Amiclaran (TN) |
|---|
| Formula |
C6H8ClN7O
|
|---|
| Exact mass |
229.0479
|
|---|
| Mol weight |
229.63
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG01885 Potassium-sparing diuretic
|
|---|
| Remark |
| Product (DG00275): | D00649<US> |
|
|---|
| Efficacy |
Diuretic, Epithelial sodium channel blocker |
|---|
| Comment |
potassium-sparing diuretic
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04960 | Aldosterone-regulated sodium reabsorption |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C03 DIURETICS
C03D ALDOSTERONE ANTAGONISTS AND OTHER POTASSIUM-SPARING AGENTS
C03DB Other potassium-sparing agents
C03DB01 Amiloride
D07447 Amiloride (INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01885 Potassium-sparing diuretic
DG00275 Amiloride
D07447 Amiloride
Target-based classification of drugs [BR:br08310]
Ion channels
Ligand-gated ion channels
Epithelial sodium channel (SCNN)
SCNN1
D07447 Amiloride (INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01885 Potassium-sparing diuretic
DG00275 Amiloride
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 15
1 C8y C 23.5900 -17.9200
2 C5a C 24.7800 -18.6200
3 C8y C 23.5900 -16.5200
4 N5x N 22.3300 -18.6200
5 N1b N 25.9700 -17.9200
6 O5a O 24.7800 -20.0200
7 N5x N 22.3300 -15.8200
8 N1a N 24.7800 -15.8200
9 C8y C 21.1400 -17.9200
10 C2c C 27.1600 -18.6200
11 C8y C 21.1400 -16.5200
12 X Cl 19.9500 -18.6200
13 N1a N 28.4200 -17.9200
14 N2a N 27.1600 -20.0200
15 N1a N 19.9500 -15.8200
BOND 15
1 1 2 1
2 1 3 1
3 1 4 2
4 2 5 1
5 2 6 2
6 3 7 2
7 3 8 1
8 4 9 1
9 5 10 1
10 7 11 1
11 9 12 1
12 10 13 1
13 10 14 2
14 11 15 1
15 9 11 2
|
|---|
