KEGG ORTHOLOGY: K04825

ORTHOLOGY: K04825

Entry

K04825                      KO

Symbol

SCNN1B, ENACB

Name

amiloride-sensitive sodium channel subunit beta

Pathway

map04742

Taste transduction

map04960

Aldosterone-regulated sodium reabsorption

Disease

H00242

Liddle syndrome

H00243

Renal tubular acidosis type 4

H00892

Bronchiectasis with or without elevated sweat chloride

H01633

High blood pressure

H02310

Renal tubular acidosis

Brite

KEGG Orthology (KO) [BR:ko00001]
09150 Organismal Systems
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    K04825  SCNN1B, ENACB; amiloride-sensitive sodium channel subunit beta
  09157 Sensory system
   04742 Taste transduction
    K04825  SCNN1B, ENACB; amiloride-sensitive sodium channel subunit beta
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K04825  SCNN1B, ENACB; amiloride-sensitive sodium channel subunit beta
Ion channels [BR:ko04040]
Ligand-gated channels
  Epithelial sodium channel (ENaC)
   K04825  SCNN1B, ENACB; amiloride-sensitive sodium channel subunit beta

Other DBs

GO:

0015280

TC:

1.A.6.1.1

Genes

HSA:	6338(SCNN1B)

PTR:	453984(SCNN1B)

PPS:	100967758(SCNN1B)

GGO:	101139786(SCNN1B)

PON:

100437410

PPYG:

129016290

NLE:	100590266(SCNN1B)

HMH:	116471135(SCNN1B)

SSYN:

129457514(SCNN1B)

MCC:	700093(SCNN1B)

MCF:	102144896(SCNN1B)

MTHB:

126944387

MNI:	105485016(SCNN1B)

CSAB:

103229709(SCNN1B)

CATY:

105586200(SCNN1B)

PANU:

101005500(SCNN1B)

TGE:	112614392(SCNN1B)

MLEU:

105545162(SCNN1B)

RRO:	104658244(SCNN1B)

RBB:	108538845(SCNN1B)

TFN:	117087498(SCNN1B)

PTEH:

111524203(SCNN1B)

CANG:

105523499(SCNN1B)

CJC:	100400682(SCNN1B)

SBQ:	101034739(SCNN1B)

CIMI:

108308520(SCNN1B)

ANAN:

105725447(SCNN1B)

CSYR:

103262324(SCNN1B)

MMUR:

105879731(SCNN1B)

LCAT:

123632480(SCNN1B)

ERUF:

138394641(SCNN1B)

PCOQ:

105810902(SCNN1B)

OGA:	100967115(SCNN1B)

MMU:	20277(Scnn1b)

MCAL:

110298060(Scnn1b)

MPAH:

110332363(Scnn1b)

RNO:	24767(Scnn1b)

MCOC:

116102904(Scnn1b)

ANU:	117721624(Scnn1b)

ASYL:

127679187(Scnn1b)

MUN:	110550638(Scnn1b)

CGE:	100754564(Scnn1b)

MAUA:

101826312(Scnn1b)

PROB:

127228285(Scnn1b)

PLEU:

114692194(Scnn1b)

PMAV:

102927021(Scnn1b)

MORG:

121457864(Scnn1b)

MFOT:

126502383

AAMP:

119800333(Scnn1b)

CNL:	130879812(Scnn1b)

NGI:	103742738(Scnn1b)

HGL:	101717352(Scnn1b)

CPOC:

100270805(Scnn1b)

CCAN:

109678009

DORD:

105981815(Scnn1b)

DSP:	122116178(Scnn1b)

DMER:

138815063(Scnn1b)

PLOP:

125341037(Scnn1b)

NCAR:

124970677

MMMA:

107146863(Scnn1b)

ITI:	101976617(Scnn1b)

OCU:	100009564(SCNN1B)

OPI:	101521479(SCNN1B)

OCZ:	121152005(SCNN1B)

TUP:	102499999(SCNN1B)

GVR:	103586909(SCNN1B)

CFA:	489972(SCNN1B)

CLUD:

112640243(SCNN1B)

VVP:	112908303(SCNN1B)

VLG:	121486760(SCNN1B)

NPO:	129520129(SCNN1B)

AML:	100476005(SCNN1B)

UMR:	103668861(SCNN1B)

UAH:	113267571(SCNN1B)

UAR:	123778804(SCNN1B)

ELK:

111162305

LLV:

125090464

MPUF:

101671836(SCNN1B)

MNP:	132026818(SCNN1B)

MLK:	131819534(SCNN1B)

NVS:	122895572(SCNN1B)

ORO:	101383943(SCNN1B)

EJU:	114198799(SCNN1B)

ZCA:	113932542(SCNN1B)

MLX:	117999134(SCNN1B)

NSU:	110577516(SCNN1B)

LWW:	102735141(SCNN1B)

FCA:	101099767(SCNN1B)

PYU:	121019384(SCNN1B)

PCOO:

112853246(SCNN1B)

PBG:	122471557(SCNN1B)

PVIV:

125154834(SCNN1B)

LRUF:

124518010

LGF:	123589483(SCNN1B)

AJU:

106970457

PTG:	102958824(SCNN1B)

PPAD:

109255567(SCNN1B)

PUC:

125927957

PLEZ:

122209444(SCNN1B)

HHV:	120233248(SCNN1B)

BTA:	533355(SCNN1B)

BOM:	102287562(SCNN1B)

BIU:	109578236(SCNN1B)

BBUB:

102411235(SCNN1B)

BKE:	129637515(SCNN1B)

BBIS:

104986576(SCNN1B)

CHX:	100861026(SCNN1B)

OAS:	100170325(SCNN1B)

BTAX:

128043370(SCNN1B)

CSUM:

138075860(SCNN1B)

ODA:	120876096(SCNN1B)

MREE:

136160604(SCNN1B)

OVR:	110125200(SCNN1B)

MBEZ:

129545454(SCNN1B)

SSC:	100627971(SCNN1B)

CFR:	102513946(SCNN1B)

CBAI:

105073679(SCNN1B)

CDK:	105094823(SCNN1B)

VPC:	102545528(SCNN1B)

BACU:

103004408(SCNN1B)

BMUS:

118881798(SCNN1B)

LVE:	103087608(SCNN1B)

OOR:	101274016(SCNN1B)

LALB:

132506465(SCNN1B)

GMF:	115861093(SCNN1B)

DDP:	132438074(SCNN1B)

DLE:	111182245(SCNN1B)

PCAD:

102978342(SCNN1B)

PSIU:

116739633(SCNN1B)

PPHC:

136134369(SCNN1B)

NASI:

112399393(SCNN1B)

ECB:	100069008(SCNN1B)

EPZ:	103540201(SCNN1B)

EAI:	106846153(SCNN1B)

MYB:	102261552(SCNN1B)

MYD:	102759519(SCNN1B)

MMYO:

118656314(SCNN1B)

MLF:	102427602(SCNN1B)

MDT:	132232657(SCNN1B)

MYUM:

139009388(SCNN1B)

PKL:	118731494(SCNN1B)

EFUS:

103296202(SCNN1B)

MNA:	107544753(SCNN1B)

DRO:	112304784(SCNN1B)

SHON:

119003978(SCNN1B)

AJM:	119045682(SCNN1B)

PDIC:

114493335(SCNN1B)

PHAS:

123825637(SCNN1B)

MMF:	118641780(SCNN1B)

PPAM:

129076798(SCNN1B)

RFQ:	117019844(SCNN1B)

PALE:

102896528(SCNN1B)

PGIG:

120584517(SCNN1B)

PVP:	105301677(SCNN1B) 105310201

RAY:	107516104(SCNN1B)

MJV:	108404704(SCNN1B)

TOD:	119241830(SCNN1B)

SARA:

101552078(SCNN1B)

SFUM:

130045993(SCNN1B)

SETR:

126031242(SCNN1B)

LAV:	100673712(SCNN1B)

TMU:

101354417

ETF:	101659429(SCNN1B)

DNM:	101422666(SCNN1B)

MDO:	100027536(SCNN1B)

GAS:	123231076(SCNN1B)

SHR:	100929720(SCNN1B)

AFZ:

127540198

PCW:	110202460(SCNN1B)

TVP:	118832115(SCNN1B)

PBRV:

138162190(SCNN1B)

MLAO:

141495186(SCNN1B)

OAA:	100079130(SCNN1B)

TACU:

119941788(SCNN1B)

GGA:	427673(SCNN1B)

PCOC:

116237509(SCNN1B)

MGP:	100543688(SCNN1B)

CJO:	107320790(SCNN1B)

TPAI:

128079387(SCNN1B)

LMUT:

125700849(SCNN1B)

NMEL:

110405603(SCNN1B)

APLA:

101795138(SCNN1B)

AACU:

137864821(SCNN1B)

ACYG:

106046021(SCNN1B)

CATA:

118256362(SCNN1B)

AFUL:

116495310(SCNN1B)

TGU:	100226405(SCNN1B)

LSR:	110479552(SCNN1B)

SCAN:

103817558(SCNN1B)

PMOA:

120513297(SCNN1B)

OTC:	121334528(SCNN1B)

PRUF:

121365835(SCNN1B)

ATRC:

139598401(SCNN1B)

GFR:	102043750(SCNN1B)

FAB:	101810758(SCNN1B)

OMA:	130259407(SCNN1B)

PHI:	102113494(SCNN1B)

PMAJ:

107211392(SCNN1B)

CCAE:

111936208(SCNN1B)

CCW:	104684728(SCNN1B)

CBRC:

103615505(SCNN1B)

ACOE:

138118747(SCNN1B)

ETL:	114061448(SCNN1B)

ZAB:	102063742(SCNN1B)

ZLE:	135454109(SCNN1B)

ACHL:

103801422(SCNN1B)

SVG:	106859260(SCNN1B)

MMEA:

130576476(SCNN1B)

HRT:	120759888(SCNN1B)

SATI:

136368034(SCNN1B)

CFAI:

136297683(SCNN1B)

CCIC:

134050645(SCNN1B)

FPG:	101921771(SCNN1B)

FCH:	102054757(SCNN1B)

NNT:	104404905(SCNN1B)

SHAB:

115607364(SCNN1B)

ACUN:

113485903(SCNN1B)

SURA:

141950808(SCNN1B)

TALA:

116964994(SCNN1B)

ACHC:

115335957(SCNN1B)

HLE:	104833669(SCNN1B)

AGEN:

126053373

HHAR:

128134947(SCNN1B)

BBUT:

142045347(SCNN1B)

GCL:

127022321

CSTI:

104556260(SCNN1B)

LDI:	104351651(SCNN1B)

DPUB:

104306929(SCNN1B)

PPUS:

135180666(SCNN1B)

AVIT:

104272428(SCNN1B)

BRHI:

104492574(SCNN1B)

EGZ:	104134531(SCNN1B)

NNI:	104015154(SCNN1B)

PARX:

142062333(SCNN1B)

PADL:

103913932(SCNN1B)

AFOR:

103904943(SCNN1B)

FGA:	104069341(SCNN1B)

CBOR:

142089309(SCNN1B)

CBOY:

140658960(SCNN1B)

MAME:

142415947(SCNN1B)

CLV:	102088625(SCNN1B)

CNIC:

135994397(SCNN1B)

MUI:	104541896(SCNN1B)

PGUU:

104462835(SCNN1B)

EHS:	104507712(SCNN1B)

CUCA:

104065057(SCNN1B)

TEO:	104381466(SCNN1B)

BREG:

104640464(SCNN1B)

GAME:

129213423(SCNN1B)

OHA:	104327401(SCNN1B)

ACAR:

104524493(SCNN1B)

CPEA:

104393104(SCNN1B)

CVF:	104295469(SCNN1B)

RTD:	128914353(SCNN1B)

CRID:

134519175(SCNN1B)

LMIC:

141747338(SCNN1B)

NARQ:

141471722(SCNN1B)

AAM:	106486203(SCNN1B)

AROW:

112975632(SCNN1B)

NPD:	112960017(SCNN1B)

TGT:	104569290(SCNN1B)

DNE:	112985379(SCNN1B)

SCAM:

104138972(SCNN1B)

ASN:	102386268(SCNN1B)

AMJ:	102575151(SCNN1B)

CPOO:

109314593(SCNN1B)

GGN:	109294436(SCNN1B)

PSS:	102448819(SCNN1B)

CIZ:	142021831(SCNN1B)

CMY:	102932288 102932510

CCAY:

125643374

LKP:	140918037 140918038

NDS:	141994632 141994688

DCC:	119862171 119862894

CPIC:

101947270(SCNN1B)

TST:	117883498(SCNN1B)

CABI:

116816754(SCNN1B)

MRV:	120373993(SCNN1B)

ACS:	100567232(scnn1b)

ASAO:

132781900(SCNN1B)

PVT:	110085048(SCNN1B)

SUND:

121914537(SCNN1B)

PBI:	103063383(SCNN1B)

PMUR:

107302602(SCNN1B)

CTIG:

120310826(SCNN1B)

TSR:	106553453(SCNN1B)

PGUT:

117667332(SCNN1B)

PCAE:

139325100(SCNN1B)

APRI:

131185394(SCNN1B)

PTEX:

113438583(SCNN1B)

VKO:	123034842(SCNN1B)

PMUA:

114584788(SCNN1B)

PRAF:

128401758(SCNN1B)

ZVI:	118092563(SCNN1B)

HCG:	128336620(SCNN1B)

GJA:	107126206(SCNN1B)

STOW:

125431479(SCNN1B)

EMC:	129340137(SCNN1B)

XLA:	378536(scnn1b.L) 397893(scnn1b.S)

XTR:	779891(scnn1b)

NPR:	108783710(SCNN1B)

RTEM:

120943390(SCNN1B)

ACAT:

141148873(SCNN1B)

PADS:

140335281(SCNN1B)

BBUF:

121007414(SCNN1B)

BGAR:

122945734(SCNN1B)

DTC:	141057106(SCNN1B)

PWL:	138261053(SCNN1B)

MUO:	115476501(SCNN1B)

GSH:	117368921(SCNN1B)

PSEX:

120542888

LCM:	102355590(SCNN1B)

CMK:

RTP:

CPLA:

CPUN:

HOC:

SCAU:

LERI:

HAKA:

PMRN:

116946274(SCNN1B)

LRJ:	133353443 133353493

LVG:

AFIL:

ABRU:

HRF:

HASI:

MAEA:

NVE:

MCAZ:

MFOO:

SPIS:

Reference

PMID:7490094

Authors

Voilley N, Bassilana F, Mignon C, Merscher S, Mattei MG, Carle GF, Lazdunski M, Barbry P

Title

Cloning, chromosomal localization, and physical linkage of the beta and gamma subunits (SCNN1B and SCNN1G) of the human epithelial amiloride-sensitive sodium channel.

Journal

Genomics 28:560-5 (1995)
DOI:10.1006/geno.1995.1188

Sequence

[hsa:6338]

LinkDB

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