KEGG   DRUG: DetomidineHelp
Entry
D07795                      Drug                                   

Name
Detomidine (INN)
Formula
C12H14N2
Exact mass
186.1157
Mol weight
186.253
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Cardiovascular agent
 DG01456  Adrenergic receptor agonist
  DG01450  alpha-Adrenergic receptor agonist
   DG01449  alpha2-Adrenergic receptor agonist
    DG01655  alpha2-adrenergic receptor specific agonist
Remark
Chemical structure group: DG01318
Efficacy
Analgesic (veterinary), Sedative-hypnotic (veterinary), alpha2-Adrenergic receptor agonist
Target
ADRA2 [HSA:150 151 152] [KO:K04138 K04139 K04140]
Interaction
Drug interaction
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    ADRA2
     D07795  Detomidine (INN)
BRITE hierarchy
Other DBs
CAS: 76631-46-4
PubChem: 96024492
ChEMBL: CHEMBL2110829
LigandBox: D07795
NIKKAJI: J126.300E
LinkDB All DBs
KCF data Show

ATOM        14
            1   C8y C    21.2800  -17.9200
            2   C8x C    21.2800  -19.3200
            3   C8x C    22.4700  -20.0200
            4   C8x C    23.7300  -19.3200
            5   C8y C    23.7300  -17.9200
            6   C8y C    22.4700  -17.2200
            7   C8x C    26.1100  -19.3200
            8   C8y C    26.1100  -17.9200
            9   C1b C    24.9200  -17.2200
            10  N4x N    27.4400  -19.7400
            11  C8x C    28.2800  -18.6200
            12  N5x N    27.4400  -17.5000
            13  C1a C    22.4700  -15.8200
            14  C1a C    20.0900  -17.2200
BOND        15
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     7   8 2
            8     8   9 1
            9     5   9 1
            10    7  10 1
            11   10  11 1
            12   11  12 2
            13    8  12 1
            14    6  13 1
            15    1  14 1

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