KEGG   DRUG: Losartan potassium and hydrochlorothiazide tabletsHelp
Entry
D07895            Mixture   Drug                                   

Name
Losartan potassium and hydrochlorothiazide tablets (JP17);
Hydrochlorothiazide - losartan potassium mixt;
Hyzaar (TN);
Losarhyd (TN)
Product
  Generic
LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (A-S Medication Solutions), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (A-S Medication Solutions), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (ACETRIS HEALTH), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (Aidarex Pharmaceuticals LLC), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (Aidarex Pharmaceuticals LLC), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (Alembic Pharmaceuticals), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (Alembic Pharmaceuticals Limited), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (Aurobindo Pharma Limited), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (AvPAK), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (Bryant Ranch Prepack), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (Bryant Ranch Prepack), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (Bryant Ranch Prepack), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (Bryant Ranch Prepack), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (Cadila Healthcare Limited), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (DIRECT RX), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (DIRECT RX), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (Direct Rx), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (Dispensing Solutions), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (Dispensing Solutions), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (JUBILANT CADISTA PHARMACEUTICALS), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (LUPIN LIMITED), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (Lake Erie Medical DBA Quality Care Products LLC), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (Legacy Pharmaceutical Packaging), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (Lupin Pharmaceuticals), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (Macleods Pharmaceuticals Limited), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (McKesson Corporation), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (MedVantx), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (NorthStar Rx LLC), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (NuCare Pharmaceutiacals), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (NuCare Pharmaceuticals), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (NuCare Pharmaceuticals), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (NuCare Pharmaceuticals), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (NuCare Pharmaceuticals), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (NuCare Pharmaceuticals), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (NuCare Pharmaceuticals), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (NuCare Pharmaceuticals), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (NuCare Pharmaceuticals), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (NuCare Pharmaceuticals), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (NuCare Pharmaceuticals), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (NuCare Pharmaceuticals), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (PD-Rx Pharmaceuticals), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (Preferred Pharmaceuticals), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (Preferred Pharmaceuticals), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (Preferred Pharmaceuticals), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (Preferred Pharmaceuticals), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (Proficient Rx LP), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (Proficient Rx LP), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (Proficient Rx LP), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (Proficient Rx LP), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (Proficient Rx LP), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (Proficient Rx LP), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (Proficient Rx LP), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (QPharma), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (REMEDYREPACK), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (REMEDYREPACK), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (REMEDYREPACK), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (REMEDYREPACK), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (REMEDYREPACK), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (REMEDYREPACK), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (Rebel Distributors Corp), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (Rebel Distributors Corp), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (Rising Health), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (Solco Healthcare US), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (St. Marys Medical Park Pharmacy), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (Teva Pharmaceuticals USA), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (Torrent Pharmaceuticals Limited), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (Unichem Pharmaceuticals (USA)), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (Unit Dose Services), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (Unit Dose Services), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (Unit Dose Services), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (Watson Laboratories), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (West-Ward Pharmaceuticals Corp.), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (Zydus Pharmaceuticals (USA)), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (PD-Rx Pharmaceuticals), LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (Sandoz)
Component
Hydrochlorothiazide [DR:D00340], Losartan potassium [DR:D00357]
Class
Cardiovascular agent
 DG01925  Renin-angiotensin system inhibitor
Enzyme substrate
 DG01642  CYP2C9 substrate
Remark
Therapeutic category: 2149
ATC code: C09DA01
Product: D07895<JP/US>
Efficacy
Antihypertensive
  Disease
Hypertension [DS:H01633]
Metabolism
Enzyme: CYP2C9 [HSA:1559]
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C09 AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM
   C09D ANGIOTENSIN II ANTAGONISTS, COMBINATIONS
    C09DA Angiotensin II antagonists and diuretics
     C09DA01 Losartan and diuretics
      D07895  Losartan potassium and hydrochlorothiazide tablets (JP17) <JP/US>
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  21  Cardiovascular agents
   214  Antihypertensives
    2149  Others
     D07895  Losartan potassium and hydrochlorothiazide tablets (JP17)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D07895  Losartan potassium and hydrochlorothiazide tablets
BRITE hierarchy
Other DBs
PubChem: 96024591
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