| Entry |
|
|---|
| Name |
Gabexate mesilate (JP18);
Gabexate mesylate;
Arodate (TN) |
|---|
| Formula |
C16H23N3O4. CH4SO3
|
|---|
| Exact mass |
417.1570
|
|---|
| Mol weight |
417.48
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Blood modifier agent
DG01950 Antithrombotic agent
|
|---|
| Remark |
| Therapeutic category: | 3999 |
| Product (DG01400): | D01672<JP> |
|
|---|
| Efficacy |
Anticoagulant, Proteolytic enzyme inhibitor |
|---|
| Target |
|
|---|
| Pathway |
| hsa04610 | Complement and coagulation cascades |
|
|---|
| Interaction |
|
|---|
| Structure map |
|
|---|
| Brite |
Therapeutic category of drugs in Japan [BR:br08301]
3 Agents affecting metabolism
39 Other agents affecting metabolism
399 Miscellaneous
3999 Others
D01672 Gabexate mesilate (JP18)
Drug groups [BR:br08330]
Blood modifier agent
DG01950 Antithrombotic agent
DG01400 Gabexate
D01672 Gabexate mesilate
Target-based classification of drugs [BR:br08310]
Peptidases and inhibitors
Serine peptidases
Chymotrypsin family
KLK
D01672 Gabexate mesilate (JP18) <JP>
KLKB1
D01672 Gabexate mesilate (JP18) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D01672 Gabexate mesilate
Drug groups [BR:br08330]
Blood modifier agent
DG01950 Antithrombotic agent
DG01400 Gabexate
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 28
1 C8y C 26.0098 -16.3177
2 O7a O 27.2208 -17.0188
3 C7a C 28.4319 -16.3177
4 C1b C 29.6429 -17.0188
5 C1b C 30.8540 -16.3177
6 C1b C 32.0650 -17.0188
7 C1b C 33.2761 -16.3177
8 C1b C 34.4871 -17.0188
9 N1b N 35.6982 -16.3177
10 C2c C 36.9092 -17.0188
11 N1a N 38.1203 -16.3177
12 N2a N 36.9092 -18.4211
13 O6a O 28.4319 -14.9154
14 C8x C 26.0115 -14.9183
15 C8x C 24.8004 -14.2172
16 C8y C 23.5877 -14.9154
17 C8x C 23.5860 -16.3148
18 C8x C 24.7970 -17.0159
19 C7a C 22.3766 -14.2071
20 O7a O 21.1656 -14.9013
21 C1b C 19.9545 -14.2002
22 C1a C 18.7435 -14.8942
23 O6a O 22.3827 -12.8049
24 S4a S 20.3771 -18.1493
25 O1d O 20.3842 -16.7470
26 O1d O 20.3842 -19.5516
27 C1a C 18.9748 -18.1493
28 O1d O 21.7794 -18.1493
BOND 27
1 6 7 1
2 7 8 1
3 3 4 1
4 1 14 2
5 14 15 1
6 15 16 2
7 16 17 1
8 17 18 2
9 18 1 1
10 8 9 1
11 16 19 1
12 1 2 1
13 19 20 1
14 9 10 1
15 20 21 1
16 4 5 1
17 21 22 1
18 10 11 1
19 19 23 2
20 10 12 2
21 5 6 1
22 3 13 2
23 2 3 1
24 24 25 2
25 24 26 2
26 24 27 1
27 24 28 1
|
|---|
