KEGG ORTHOLOGY: K01324

ORTHOLOGY: K01324

Entry

K01324                      KO

Symbol

KLKB1

Name

plasma kallikrein [EC:3.4.21.34]

Pathway

map04610

Complement and coagulation cascades

Disease

H01078

Fletcher factor deficiency

Brite

KEGG Orthology (KO) [BR:ko00001]
09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    K01324  KLKB1; plasma kallikrein
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K01324  KLKB1; plasma kallikrein
Enzymes [BR:ko01000]
3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.34  plasma kallikrein
     K01324  KLKB1; plasma kallikrein
Peptidases and inhibitors [BR:ko01002]
Serine peptidases
  Family S1: chymotrypsin family
   K01324  KLKB1; plasma kallikrein

Genes

HSA:	3818(KLKB1)

PTR:	471375(KLKB1)

PPS:	100985593(KLKB1)

GGO:	101142617(KLKB1)

PON:	100172926(KLKB1)

NLE:	100594044 115835879

MCC:	696639(KLKB1)

MCF:	102142369(KLKB1)

CSAB:

103236637(KLKB1)

CATY:

105594265(KLKB1)

PANU:

101004320(KLKB1)

TGE:	112624825(KLKB1)

RRO:	104673817(KLKB1)

RBB:	108522428(KLKB1)

TFN:	117086226(KLKB1)

PTEH:

111548503(KLKB1)

CJC:	100409572(KLKB1)

SBQ:	101048983(KLKB1)

CSYR:

103271965(KLKB1)

MMUR:

105882474(KLKB1)

OGA:	100950732(KLKB1)

MMU:	16621(Klkb1)

MCAL:

110299702(Klkb1)

MPAH:

110336817(Klkb1)

RNO:	25048(Klkb1)

MCOC:

116071383(Klkb1)

MUN:	110558008(Klkb1)

CGE:	100767873(Klkb1)

PLEU:

114701164(Klkb1)

NGI:	103750509(Klkb1)

HGL:	101719264(Klkb1)

CPOC:

100715794(Klkb1)

CCAN:

109684302(Klkb1)

DORD:

105991332(Klkb1)

DSP:	122127383(Klkb1)

NCAR:

124983746

OCU:	100356267(KLKB1)

OPI:	101523823(KLKB1)

TUP:	102485674(KLKB1)

CFA:	475624(KLKB1)

VVP:	112934777(KLKB1)

AML:	100468355(KLKB1)

UMR:	103680968(KLKB1)

UAH:	113262285(KLKB1)

UAR:	123784492(KLKB1)

ELK:

111144530

LLV:

125093973

MPUF:

101689429(KLKB1)

ORO:	101379313(KLKB1)

EJU:	114206167(KLKB1)

ZCA:	113924887(KLKB1)

MLX:	118010046(KLKB1)

FCA:	101094092(KLKB1)

PYU:	121039709(KLKB1)

PBG:	122470993(KLKB1)

PTG:	102971874(KLKB1)

PPAD:

109250991(KLKB1)

AJU:	106982221(KLKB1)

HHV:	120237791(KLKB1)

BTA:	533547(KLKB1)

BOM:	102270694(KLKB1)

BIU:	109553560(KLKB1)

BBUB:

102396882(KLKB1)

CHX:	102184030(KLKB1)

OAS:	101116376(KLKB1)

ODA:	120865743(KLKB1)

CCAD:

122432375(KLKB1)

SSC:	397144(KLKB1)

CFR:	102512343(KLKB1)

CBAI:

105067666(KLKB1)

CDK:	105102384(KLKB1)

VPC:	102526079(KLKB1)

PCAD:

112063073

ECB:	100056650(KLKB1)

EAI:	106840366(KLKB1)

MYB:	102247445(KLKB1)

MYD:	102764838(KLKB1)

MMYO:

118652088(KLKB1)

MLF:	102426918(KLKB1)

MNA:	107534033(KLKB1)

PKL:	118730055(KLKB1)

HAI:	109395838(KLKB1)

DRO:	112306752(KLKB1)

SHON:

118993096(KLKB1)

AJM:	119036873(KLKB1)

PDIC:

114508386(KLKB1)

PHAS:

123807510(KLKB1)

RFQ:	117021760(KLKB1)

PALE:

102883484(KLKB1)

PGIG:

120618463(KLKB1)

PVP:	105294687(KLKB1)

RAY:	107510433(KLKB1)

MJV:	108396405(KLKB1)

TOD:	119230348 119257004(KLKB1)

SARA:

101551391(KLKB1)

LAV:

100660779

TMU:

101358166

DNM:	101423717(KLKB1)

MDO:	100013981(KLKB1)

GAS:	123253136(KLKB1)

SHR:	100917450(KLKB1)

PCW:	110204309 110204628

OAA:

100086786

GGA:	422723(F11)

PCOC:

MGP:

CJO:

NMEL:

APLA:

ACYG:

AFUL:

TGU:

LSR:

SCAN:

PMOA:

OTC:

PRUF:

GFR:	102045543(F11)

FAB:	101814154(KLKB1)

PHI:	102108065(F11)

PMAJ:

107203558

CCAE:

111927976

CCW:	104690592(KLKB1)

ETL:

114067778

ZAB:	102073697(KLKB1)

FPG:	101918416(F11)

FCH:

CLV:

EGZ:

NNI:

ACUN:

TALA:

PADL:

ACHC:

AAM:

AROW:

NPD:

DNE:

ASN:	102385242(KLKB1)

AMJ:	102566272(KLKB1)

CPOO:

109322021

GGN:	109303759(KLKB1)

PSS:

102455335

CPIC:

101952530(KLKB1)

TST:	117878095(KLKB1)

CABI:

116835912

MRV:

120406388

ACS:	100557428(klkb1)

PVT:	110077890(KLKB1)

SUND:

121931138(KLKB1)

PBI:	103051995(KLKB1)

PMUR:

107302682

TSR:	106542021(KLKB1)

PGUT:

117680187(KLKB1)

VKO:	123036510(KLKB1)

PMUA:

114604642(KLKB1)

ZVI:	118084140(KLKB1)

GJA:	107121980(KLKB1)

XLA:	446603(klkb1.L)

XTR:	100486524(klkb1)

NPR:

108784940

RTEM:

120921901

BBUF:

120990165(KLKB1)

BGAR:

122934952(KLKB1)

IPU:

PHYP:

SMEO:

TFD:

TNG:	GSTEN00017543G001

PFLV:

114568223

MZE:

101476310

ONL:	100691143 100711845 100712382

OLA:

101167304

OML:

112136310

XMA:	102235514 102236020 111610402

XCO:	114155410 114155689 114156653

XHE:	116730704 116731571

PRET:

103472119 103472120 103472122

GAF:

122843703

CVG:

107092604

CTUL:

119784643

GMU:	124878882 124879615

NFU:

107374492

AOCE:

111572227

HHIP:

117770686

LCF:	108893005 108893006 108900438

SDU:

SLAL:

XGL:

HCQ:

ELS:

SFM:

PKI:

LOC:	102685657 107077276

LCM:	102361209(KLKB1)

RTP:

109919186

BBEL:

109472036 109485493

CIN:	100176588 100182205

SCLV:

120327917 120334500 120338190 120342435 120342461 120342776 120344424 120344858

APLC:

SKO:

MDE:

LCQ:

AAG:	5563617 5570931 5575054 5575060

AALB:

109416028 109426188

CQU:	CpipJ_CPIJ016225

CPII:

CNS:

BIM:

BTER:

SOC:	105193897 105196026 105196044 105196739 105200420

MPHA:

105831007 105832984 114253741

AEC:	105151207 105151375

ACEP:

105617847 105619958

PBAR:

105422311 105424748

VEM:

105568413

HST:	105186338 109503706

CFO:	105249589 105251050 105251056 105255493 105257558

LHU:

105671298

PGC:	109852197 109853791

NVI:	100114471(SP16) 103318165

CSOL:

105362138 105366751

ATD:

109602881

NVL:	108559693 108563022 108565242

BMOR:

BMAN:

MSEX:

BANY:

HAW:

TNL:	113499223 113500559 113505544 113505545

PXY:

API:

AGS:

RMD:

BTAB:

CLEC:

HHAL:

ZNE:

FCD:	110842752 110853210 110853426 110858603

DPX:	DAPPUDRAFT_241460

PVM:	113802726 113803371 113807483 113811742 113811866 113819716 113821989 113827133

PJA:	122246632 122248640

PCHN:

HAME:

PCLA:

PTRU:

EAF:	111700653 111707120 111715548

ISC:	IscW_ISCW011206

RSAN:

119393437

VDE:

111249763

VJA:

111266457

TUT:	107359274 107364976 107370370 107371275

DPTE:

113796590 113797445 113798611

DFR:	124490111 124493637 124498460

CSCU:

111614124 111620528 111638398

PTEP:

107440325 107442445 107456184

SDM:

118195904

HRO:	HELRODRAFT_180736

LGI:	LOTGIDRAFT_153888

PCAN:

112554714 112571496

HRF:

124116279

HRJ:	124289327 124291123

CRG:

105348511

MYI:

110443096

PMAX:

117329014

OBI:	106870435 106877341

OSN:

115217699

LAK:

106151350

OVI:	T265_14457

NVE:

5502645

AMIL:

114955798

PDAM:

113669975 113670584 113685551

SPIS:

111344747

HMG:

105847477

TGO:	TGME49_286150

GTT:	GUITHDRAFT_151304

NGR:	NAEGRDRAFT_65585

» show all

Reference

PMID:23204305

Authors

Marques PI, Bernardino R, Fernandes T, Green ED, Hurle B, Quesada V, Seixas S

Title

Birth-and-death of KLK3 and KLK2 in primates: evolution driven by reproductive biology.

Journal

Genome Biol Evol 4:1331-8 (2012)
DOI:10.1093/gbe/evs111

Reference

PMID:11031105

Authors

Yu H, Anderson PJ, Freedman BI, Rich SS, Bowden DW

Title

Genomic structure of the human plasma prekallikrein gene, identification of allelic variants, and analysis in end-stage renal disease.

Journal

Genomics 69:225-34 (2000)
DOI:10.1006/geno.2000.6330

Sequence

[hsa:3818]

LinkDB

DBGET integrated database retrieval system