KEGG   DRUG: KetamineHelp
Entry
D08098                      Drug                                   

Name
Ketamine (INN);
Tekam (TN)
Formula
C13H16ClNO
Exact mass
237.092
Mol weight
237.7252
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Neuropsychiatric agent
 DG02030  Anesthetics
  DG02027  General anesthetics
 DG02027  General anesthetics
 DG01498  NMDA receptor antagonist
Remark
Same as: C07525
ATC code: N01AX03
Chemical structure group: DG00796
Product (DG00796): D00711<JP/US>
Efficacy
Anesthetic (intravenous), NMDA receptor antagonist
Comment
Phencyclidine derivative
Target
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04724  Glutamatergic synapse
Interaction
Drug interaction
Structure map
map07235  N-Metyl-D-aspartic acid receptor antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N01 ANESTHETICS
   N01A ANESTHETICS, GENERAL
    N01AX Other general anesthetics
     N01AX03 Ketamine
      D08098  Ketamine (INN)
Target-based classification of drugs [BR:br08310]
 Ion channels
  Ligand-gated ion channels
   Glutamate (ionotropic), NMDA
    GRIN (NMDAR)
     D08098  Ketamine (INN)
BRITE hierarchy
Other DBs
CAS: 6740-88-1
PubChem: 96024788
ChEBI: 6121
ChEMBL: CHEMBL742
DrugBank: DB01221
LigandBox: D08098
NIKKAJI: J244.885H
LinkDB All DBs
KCF data Show

ATOM        16
            1   C1z C    24.9200  -17.7800
            2   C8y C    23.7300  -18.4800
            3   C5x C    26.3200  -17.7800
            4   C1x C    24.2200  -16.5900
            5   N1b N    25.6200  -18.9700
            6   C8y C    22.4700  -17.7800
            7   C8x C    23.7300  -19.8800
            8   C1x C    27.0200  -16.5200
            9   O5x O    27.0200  -18.9700
            10  C1x C    24.9200  -15.3300
            11  C1a C    24.9200  -20.2300
            12  C8x C    21.2800  -18.4800
            13  X   Cl   22.4700  -16.3800
            14  C8x C    22.4700  -20.5800
            15  C1x C    26.3200  -15.3300
            16  C8x C    21.2800  -19.8800
BOND        17
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     1   5 1
            5     2   6 2
            6     2   7 1
            7     3   8 1
            8     3   9 2
            9     4  10 1
            10    5  11 1
            11    6  12 1
            12    6  13 1
            13    7  14 2
            14    8  15 1
            15   12  16 2
            16   10  15 1
            17   14  16 1

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