KEGG   DRUG: MedetomidineHelp
Entry
D08165                      Drug                                   

Name
Medetomidine (INN);
Domitor [veterinary] (TN)
Formula
C13H16N2
Exact mass
200.1313
Mol weight
200.2795
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Cardiovascular agent
 DG01456  Adrenergic receptor agonist
  DG01450  alpha-Adrenergic receptor agonist
   DG01449  alpha2-Adrenergic receptor agonist
    DG01655  alpha2-adrenergic receptor specific agonist
Remark
Chemical structure group: DG01320
Efficacy
Analgesic (veterinary), Sedative-hypnotic (veterinary), alpha2-Adrenergic receptor agonist
Target
ADRA2 [HSA:150 151 152] [KO:K04138 K04139 K04140]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
Interaction
Drug interaction
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    ADRA2
     D08165  Medetomidine (INN)
BRITE hierarchy
Other DBs
CAS: 86347-14-0
PubChem: 96024855
ChEMBL: CHEMBL77921
LigandBox: D08165
NIKKAJI: J134.038G
LinkDB All DBs
KCF data Show

ATOM        15
            1   C8y C    21.2800  -17.9200
            2   C8x C    21.2800  -19.3200
            3   C8x C    22.4700  -20.0200
            4   C8x C    23.7300  -19.3200
            5   C8y C    23.7300  -17.9200
            6   C8y C    22.4700  -17.2200
            7   C8x C    26.1100  -19.3200
            8   C8y C    26.1100  -17.9200
            9   C1c C    24.9200  -17.2200
            10  N4x N    27.4400  -19.7400
            11  C8x C    28.2800  -18.6200
            12  N5x N    27.4400  -17.5000
            13  C1a C    24.9200  -15.8200
            14  C1a C    22.4700  -15.8200
            15  C1a C    20.0900  -17.2200
BOND        16
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     7   8 2
            8     8   9 1
            9     5   9 1
            10    7  10 1
            11   10  11 1
            12   11  12 2
            13    8  12 1
            14    9  13 1
            15    6  14 1
            16    1  15 1

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