KEGG   DRUG: MorphineHelp
Entry
D08233                      Drug                                   

Name
Morphine (BAN);
Morfina Dosa (TN);
Substitol (TN)
Formula
C17H19NO3
Exact mass
285.1365
Mol weight
285.3377
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Source
Papaver somniferum [TAX:3469]
Class
Neuropsychiatric agent
 DG01564  Opioid receptor agonist
  DG01563  mu-Opioid receptor agonist
Analgesic
 DG01984  Opioid analgesics
Remark
Same as: C01516
ATC code: N02AA01
Chemical structure group: DG00810
Product (DG00810): D00842<JP/US> D02271<JP>
Efficacy
Analgesic (narcotic), Opioid receptor agonist
Comment
Opium alkaloid
Target
OPRM1 [HSA:4988] [KO:K04215]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
Interaction
Drug interaction
Structure map
map07039  Opioid analgesics
map07224  Opioid receptor agonists/antagonists
Other map
map00982  Drug metabolism - cytochrome P450
map05032  Morphine addiction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N02 ANALGESICS
   N02A OPIOIDS
    N02AA Natural opium alkaloids
     N02AA01 Morphine
      D08233  Morphine (BAN)
USP drug classification [BR:br08302]
 Analgesics
  Opioid Analgesics, Long-acting
   Morphine
    D08233  Morphine (BAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Opioid
    OPRM1
     D08233  Morphine (BAN)
Prodrugs [br08324.html]
 D08233
BRITE hierarchy
Other DBs
CAS: 57-27-2
PubChem: 96024921
ChEBI: 17303
ChEMBL: CHEMBL3914733 CHEMBL3978843 CHEMBL70
DrugBank: DB00295
PDB-CCD: MOI[PDBj]
LigandBox: D08233
NIKKAJI: J2.323J
LinkDB All DBs
KCF data Show

ATOM        21
            1   C1z C    21.5533  -23.4873
            2   C8y C    21.5533  -22.2201
            3   C1y C    22.7502  -24.1914
            4   C1y C    20.4268  -24.1210
            5   C1x C    22.7502  -22.8537
            6   C8y C    20.4268  -21.5864
            7   C8y C    22.7502  -21.5864
            8   C1y C    23.8062  -23.4873
            9   C2x C    22.7502  -25.4587
            10  O2x O    19.0891  -22.7833
            11  C1y C    20.4268  -25.4587
            12  C1x C    24.9327  -22.8537
            13  C8y C    20.4268  -20.2487
            14  C1x C    23.8062  -22.2905
            15  C8x C    22.7502  -20.2487
            16  N1y N    24.9327  -24.1914
            17  C2x C    21.5533  -26.1627
            18  O1a O    19.3003  -26.1627
            19  C8x C    21.6237  -19.6151
            20  O1a O    19.3003  -19.6151
            21  C1a C    26.3408  -24.1914
BOND        25
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     1   5 1 #Up
            5     2   6 2
            6     2   7 1
            7     3   8 1
            8     3   9 1
            9     4  10 1 #Down
            10    4  11 1
            11    5  12 1
            12    6  13 1
            13    7  14 1
            14    7  15 2
            15    8  16 1 #Up
            16    9  17 2
            17   11  18 1 #Down
            18   13  19 2
            19   13  20 1
            20    6  10 1
            21    8  14 1
            22   11  17 1
            23   12  16 1
            24   15  19 1
            25   16  21 1

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