| Entry |
|
|---|
| Name |
Neostigmine (BAN);
Prostigmin (TN) |
|---|
| Formula |
C12H19N2O2
|
|---|
| Exact mass |
223.1447
|
|---|
| Mol weight |
223.29
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01595 Cholinesterase inhibitor
DG01593 Acetylcholinesterase inhibitor
DG01719 Parasympathomimetic agent
|
|---|
| Remark |
| Product (DG00987): | D00995<JP> D00998<JP/US> |
|
|---|
| Efficacy |
Acetylcholinesterase inhibitor |
|---|
| Comment |
Reversible cholinesterase inhibitor
Physostigmine derivative
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07220 | Cholinergic and anticholinergic drugs |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N07 OTHER NERVOUS SYSTEM DRUGS
N07A PARASYMPATHOMIMETICS
N07AA Anticholinesterases
N07AA01 Neostigmine
D08261 Neostigmine (BAN)
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01E ANTIGLAUCOMA PREPARATIONS AND MIOTICS
S01EB Parasympathomimetics
S01EB06 Neostigmine
D08261 Neostigmine (BAN)
Risk category of Japanese OTC drugs [BR:br08312]
Third-class OTC drugs
Inorganic and organic chemicals
Neostigmine
D08261 Neostigmine (BAN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01595 Cholinesterase inhibitor
DG01593 Acetylcholinesterase inhibitor
DG00987 Neostigmine
D08261 Neostigmine
DG01719 Parasympathomimetic agent
DG00987 Neostigmine
D08261 Neostigmine
Target-based classification of drugs [BR:br08310]
Enzymes
Hydrolases (EC3)
Carboxylic-ester hydrolases
ACHE
D08261 Neostigmine (BAN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01595 Cholinesterase inhibitor
DG01593 Acetylcholinesterase inhibitor
DG00987 Neostigmine
DG01719 Parasympathomimetic agent
DG00987 Neostigmine
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 16
1 C8y C 23.9400 -17.9200
2 C8x C 25.1300 -17.2200
3 C8x C 23.9400 -19.3200
4 O7a O 22.7500 -17.2200
5 C8y C 26.3200 -17.9200
6 C8x C 25.1300 -19.9500
7 C7a C 21.5600 -17.9200
8 C8x C 26.3200 -19.3200
9 N1d N 27.5100 -17.2200 #+
10 N1c N 20.3700 -17.2200
11 O6a O 21.5600 -19.3200
12 C1a C 29.1200 -16.3100
13 C1a C 26.8800 -16.1700
14 C1a C 28.2800 -18.4100
15 C1a C 19.1800 -17.9200
16 C1a C 20.3700 -15.8900
BOND 16
1 1 2 2
2 1 3 1
3 1 4 1
4 2 5 1
5 3 6 2
6 4 7 1
7 5 8 2
8 5 9 1
9 7 10 1
10 7 11 2
11 9 12 1
12 9 13 1
13 9 14 1
14 10 15 1
15 10 16 1
16 6 8 1
|
|---|
